Results 41 to 50 of about 7,378 (211)
Frontiers in Cellular Neuroscience, 2022 Retinal ganglion cells expressing the photopigment melanopsin are intrinsically photosensitive (ipRGCs). ipRGCs regulate subconscious non-image-forming behaviors such as circadian rhythms, pupil dilation, and light-mediated mood.
Sadaf Abed +3 more
doaj +1 more source
Myopes have significantly higher serum melatonin concentrations than non-myopes [PDF]
, 2017 Purpose Experimental animal models of myopia demonstrate that higher melatonin (Mel) and lower dopamine (DA) concentrations actively promote axial elongation.
Ackermann +70 more
core +2 more sources
Retrograde Melanopsin Signaling Increases With Age in Retinal Degenerate Mice Lacking Rods and the Majority of Cones [PDF]
, 2016 PURPOSE: Following on from reports of retrograde retinal signaling in mice, we sought to investigate the influence of age and retinal location on this phenomenon using mice that lack rods and the majority of cones. METHODS: We used functional anatomy for
Coffey, P, Gias, C, Semo, M, Vugler, A
core +1 more source
Comparison of acute non-visual bright light responses in patients with optic nerve disease, glaucoma and healthy controls. [PDF]
, 2015 This study examined the effect of optic nerve disease, hence retinal ganglion cell loss, on non-visual functions related to melanopsin signalling. Test subjects were patients with bilateral visual loss and optic atrophy from either hereditary optic ...
Collomb, S. +3 more
core +1 more source
Central projections of melanopsin‐expressing retinal ganglion cells in the mouse [PDF]
Journal of Comparative Neurology, 2006 AbstractA rare type of ganglion cell in mammalian retina is directly photosensitive. These novel retinal photoreceptors express the photopigment melanopsin. They send axons directly to the suprachiasmatic nucleus (SCN), intergeniculate leaflet (IGL), and olivary pretectal nucleus (OPN), thereby contributing to photic synchronization of circadian ...
Samer, Hattar +6 more
openaire +2 more sources
Form vision from melanopsin in humans
Nature Communications, 2019 The perception of spatial patterns (form vision) is thought to rely on rod and cone cells in the retina. Here, the authors show that a third kind of retinal cell, melanopsin-expressing ganglion cells, can also detect form in humans, under particular ...
Annette E. Allen +2 more
doaj +1 more source
Cross‐Sectional and Longitudinal Associations of the Pupillary Light Response with Mild Cognitive Impairment [PDF]
Alzheimers DementAbstract Background Pupillary light response (PLR) alterations have been observed in individuals with Alzheimer's disease and related dementias (ADRD). Little is known about the predictive utility of the PLR as a biomarker for ADRD or general cognitive decline.
Panizzon M +7 more
europepmc +2 more sources
Retinal Ganglion Cells and Circadian Rhythms in Alzheimer’s Disease, Parkinson’s Disease, and Beyond
Frontiers in Neurology, 2017 There is increasing awareness on the role played by circadian rhythm abnormalities in neurodegenerative disorders such as Alzheimer’s disease (AD) and Parkinson’s disease (PD).
Chiara La Morgia +6 more
doaj +1 more source
Melanopsin-derived visual responses under light adapted conditions in the mouse dLGN.
PLoS ONE, 2015 A direct projection from melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs) reaches the primary visual thalamus (dorsal lateral geniculate nucleus; dLGN).
Katherine E Davis +4 more
doaj +1 more source
PLoS ONE, 2014 We report that the most common retinal ganglion cell type that remains after optic nerve transection is the M1 melanopsin ganglion cell. M1 ganglion cells are members of the intrinsically photosensitive retinal ganglion cell population that mediates non ...
Luis Pérez de Sevilla Müller +3 more
doaj +1 more source