Nocturnal enhancement of plasma melatonin could be suppressed by benzodiazepines in humans.
Michinori Kabuto+2 more
openalex +1 more source
Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases
HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang+4 more
wiley +1 more source
Melatonin Plays a Protective Role in Postburn Rodent Gut Pathophysiology
Melatonin is a possible protective agent in postburn gut pathophysiological dynamics. We investigated the role of endogenously-produced versus exogenously-administered melatonin in a major thermal injury rat model with well-characterized gut inflammatory
Walid M. Al-Ghoul, Steven Abu-Shaqra, Byeong Gyu Park, Nadeem Fazal
doaj
Myopes have significantly higher serum melatonin concentrations than non-myopes [PDF]
Ackermann+70 more
core +2 more sources
Salivary melatonin estimation in assessment of pineal-gland function. [PDF]
A Miles, D R Philbrick, J E Grey
openalex +1 more source
Medication‐resistant epilepsy is associated with a unique gut microbiota signature
Abstract Objective Dysfunction of the microbiota–gut–brain axis is emerging as a new pathogenic mechanism in epilepsy, potentially impacting on medication response and disease outcome. We investigated the composition of the gut microbiota in a cohort of medication‐resistant (MR) and medication‐sensitive (MS) pediatric patients with epilepsy.
Antonella Riva+14 more
wiley +1 more source
CALCEMIC RESPONSES TO PHOTIC AND PHARMACOLOGIC MANIPULATION OF SERUM MELATONIN [PDF]
David O. Hakanson+2 more
openalex +1 more source
In vitro models of valproic acid to assess neurodevelopmental toxicity: A scoping review
Abstract Valproic acid (VPA) is a first‐line antiseizure medication (ASM) that is highly efficacious for treating generalized and focal epilepsy disorders. Unfortunately, due to its strong association with teratogenic effects culminating in fetal valproate spectrum disorder (FVSD), which may include neurocognitive and neurobehavioral deficits, the drug
Daniel Sandvik+5 more
wiley +1 more source
Upregulated Expression and Shifted Distribution of Melatonin and Its Synthesizing Enzymes From Postnatal to Young Adult Rat Cochleae. [PDF]
Orsolic M+3 more
europepmc +1 more source