Results 181 to 190 of about 181,700 (339)

Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases

open access: yesCell Proliferation, EarlyView.
HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang   +4 more
wiley   +1 more source

Melatonin Plays a Protective Role in Postburn Rodent Gut Pathophysiology

open access: yesInternational Journal of Biological Sciences, 2010
Melatonin is a possible protective agent in postburn gut pathophysiological dynamics. We investigated the role of endogenously-produced versus exogenously-administered melatonin in a major thermal injury rat model with well-characterized gut inflammatory
Walid M. Al-Ghoul, Steven Abu-Shaqra, Byeong Gyu Park, Nadeem Fazal
doaj  

Myopes have significantly higher serum melatonin concentrations than non-myopes [PDF]

open access: yes, 2017
Ackermann   +70 more
core   +2 more sources

Medication‐resistant epilepsy is associated with a unique gut microbiota signature

open access: yesEpilepsia, EarlyView.
Abstract Objective Dysfunction of the microbiota–gut–brain axis is emerging as a new pathogenic mechanism in epilepsy, potentially impacting on medication response and disease outcome. We investigated the composition of the gut microbiota in a cohort of medication‐resistant (MR) and medication‐sensitive (MS) pediatric patients with epilepsy.
Antonella Riva   +14 more
wiley   +1 more source

CALCEMIC RESPONSES TO PHOTIC AND PHARMACOLOGIC MANIPULATION OF SERUM MELATONIN [PDF]

open access: bronze, 1984
David O. Hakanson   +2 more
openalex   +1 more source

Melatonin madness

open access: yesCell, 1995
Reppert, Steven M., Weaver, David R.
openaire   +2 more sources

In vitro models of valproic acid to assess neurodevelopmental toxicity: A scoping review

open access: yesEpilepsia, EarlyView.
Abstract Valproic acid (VPA) is a first‐line antiseizure medication (ASM) that is highly efficacious for treating generalized and focal epilepsy disorders. Unfortunately, due to its strong association with teratogenic effects culminating in fetal valproate spectrum disorder (FVSD), which may include neurocognitive and neurobehavioral deficits, the drug
Daniel Sandvik   +5 more
wiley   +1 more source

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