Results 241 to 250 of about 118,918 (292)

Melatonin ameliorates cognitive deficits through improving mitophagy in a mouse model of Alzheimer’s disease

Journal of Pineal Research, 2021
While melatonin is known to have protective effects in mitochondria‐related diseases, aging, and neurodegenerative disorders, there is poor understanding of the effects of melatonin treatment on mitophagy in Alzheimer's disease (AD).
Chongyang Chen, Chao Yang, Jing Wang, Xi Huang, Haitao Yu, Shangming Li, Shupeng Li, Zaijun Zhang, Jianjun Liu, Xifei Yang, Gong-Ping Liu   +10 more
semanticscholar   +1 more source

Melatonin regulates the functional components of photosynthesis, antioxidant system, gene expression, and metabolic pathways to induce drought resistance in grafted Carya cathayensis plants.

Science of the Total Environment, 2020
The Chinese hickory (Carya cathayensis) is an economically important tree species popular for its nuts. However, the tree requires a long time to reach the nut-producing phase. To overcome this problem, grafting is widely used to reduce the time from the
Anket Sharma, Junfeng Wang, Dongbin Xu, Shenchen Tao, Sun-Li Chong, D. Yan, Zhen Li, Huwei Yuan, Bingsong Zheng   +8 more
semanticscholar   +1 more source

MELATONIN RADIOIMMUNOASSAY

The Journal of Clinical Endocrinology & Metabolism, 1975
A radioimmunoassay for melatonin has been developed after the raising of anti-melatonin antibodies in rabbits.
J, Arendt, L, Paunier, P C, Sizonenko
openaire   +2 more sources

Mechanistic insights on melatonin mediated drought stress mitigation in plants.

Physiologia Plantarum : An International Journal for Plant Biology, 2020
Drought stress imposes a serious threat to crop productivity and nutritional security. Drought adaptation mechanisms involve complex regulatory network comprising of various sensory and signaling molecules.
R. Tiwari, M. Lal, Ravinder Kumar, K. Chourasia, K. Naga, Dharmendra Kumar, Sourav Das, G. Zinta   +7 more
semanticscholar   +1 more source

Melatonin and Melatonin Analogues

Sleep Medicine Clinics, 2009
Over the past 25 years, there has been substantial growth in the field of melatonin and melatonin analogues. Following the first demonstration that exogenous melatonin can entrain the mammalian circadian system and the discovery of the phase-shifting and sleep-promoting properties of the hormone in humans, several groups have demonstrated the potential
Shantha M.W. Rajaratnam, Daniel A. Cohen, Naomi L. Rogers   +2 more
openaire   +1 more source

Melatonin attenuates myocardial ischemia‐reperfusion injury via improving mitochondrial fusion/mitophagy and activating the AMPK‐OPA1 signaling pathways

Journal of Pineal Research, 2019
Optic atrophy 1 (OPA1)‐related mitochondrial fusion and mitophagy are vital to sustain mitochondrial homeostasis under stress conditions. However, no study has confirmed whether OPA1‐related mitochondrial fusion/mitophagy is activated by melatonin and ...
Y. Zhang, Yue Wang, Junnan Xu, F. Tian, Shunying Hu, Yundai Chen, Zhenhong Fu   +6 more
semanticscholar   +1 more source

Deletion of ferritin H in neurons counteracts the protective effect of melatonin against traumatic brain injury‐induced ferroptosis

Journal of Pineal Research, 2020
Accumulating evidence demonstrates that ferroptosis may be important in the pathophysiological process of traumatic brain injury (TBI). As a major hormone of the pineal gland, melatonin exerts many beneficial effects on TBI, but there is no information ...
Tongyu Rui, Hao-chen Wang, Qianqian Li, Ying Cheng, Yuan Gao, X. Fang, Xuying Ma, Guangdao Chen, Cheng Gao, Z. Gu, S. Song, Jian Zhang, Chunling Wang, Zufeng Wang, Tao Wang, Mingyang Zhang, J. Min, Xi-ping Chen, L. Tao, Fudi Wang, Chengliang Luo   +20 more
semanticscholar   +1 more source

Melatonin attenuates diabetic cardiomyopathy and reduces myocardial vulnerability to ischemia‐reperfusion injury by improving mitochondrial quality control: Role of SIRT6

Journal of Pineal Research, 2020
Targeting mitochondrial quality control with melatonin has been found promising for attenuating diabetic cardiomyopathy (DCM), although the underlying mechanisms remain largely undefined.
Liming Yu, Xue Dong, Xiaodong Xue, Shu-hua Xu, Xu Zhang, Yinli Xu, Zhishang Wang, Yang Wang, Hao Gao, Yangzhi Liang, Yang Yang, Huishan Wang   +11 more
semanticscholar   +1 more source

Melatonin protects mouse testes from palmitic acid‐induced lipotoxicity by attenuating oxidative stress and DNA damage in a SIRT1‐dependent manner

Journal of Pineal Research, 2020
Palmitic acid (PA), the main component of dietary saturated fat, has been known to increase in patients with obesity, and PA‐induced lipotoxicity may contribute to obesity‐related male infertility.
Dejun Xu, Lingbin Liu, Yongju Zhao, Li Yang, Jianyong Cheng, Rongmao Hua, Zelin Zhang, Qingwang Li   +7 more
semanticscholar   +1 more source

Exogenous melatonin promotes biomass accumulation and photosynthesis of kiwifruit seedlings under drought stress

Scientia Horticulturae, 2019
Melatonin is involved in regulating plant growth and responding to multiple environmental stresses. The underlying mechanism by which melatonin mediates drought tolerance in some plant species remains unknown.
D. Liang, Zhiyou Ni, Hui Xia, Yue Xie, X. Lv, Jin Wang, Lijin Lin, Qunxian Deng, Luo Xian   +8 more
semanticscholar   +1 more source