Results 241 to 250 of about 242,415 (401)

Tryptophan Suppresses FTH1‐Driven Ferritinophagy, a Key Correlate of Prognosis in Hepatocellular Carcinoma

Cell Proliferation, EarlyView.
Intracellular tryptophan levels modulate selective autophagy of FTH1 via the NCOA4 pathway. This autophagic process then inhibits 6‐HMT synthesis, which then results in an increase in reactive oxygen species and ferroptosis. ABSTRACT Hepatocellular carcinoma (HCC) remains a lethal malignancy with limited therapeutic options.
Xinxiang Cheng, Xin Ge, Chi Zhang, Xingye Yang, Zhengxin Yu, Min Zhang, Wen Cao, Qingtao Ni, Yang Liu, Songbing He, Yin Yuan   +10 more
wiley   +1 more source

MT1 and MT2 Melatonin Receptors: A Therapeutic Perspective.

Annual Review of Pharmacology and Toxicology, 2016
Jiabei Liu, Shannon J. Clough, A. Hutchinson, E. Adamah-Biassi, Marina Popovska-Gorevski, M. Dubocovich   +5 more
semanticscholar   +1 more source

Social disadvantage is associated with impaired increase in salivary diurnal melatonin amplitude throughout pregnancy. [PDF]

Sleep Adv
McCarthy RT, Reinl EL, Strutz PK, Zhao P, Esparza A, Sass ER, Schoening M, Kaginele P, Shi N, Canal M, Chubiz JE, Fay JC, Jungheim ES, Raghuraman N, Kent LN, Cox RC, Frolova AI, Herzog ED, England SK.   +18 more
europepmc   +1 more source

Effect of a photoperiodic green light programme during incubation on embryo development and hatch process [PDF]

, 2018
Berckmans, D, Bergoug, H, Demmers, T G M, Eterradossi, N, Exadaktylos, V, Guinebretiere, M, McGonnell, I M, Romanini, C E, Roulston, N, Tong, Q, Verhelst, R   +10 more
core   +1 more source

Nocturnal enhancement of plasma melatonin could be suppressed by benzodiazepines in humans.

, 1986
Michinori Kabuto, IKUO NAMURA, Youichi Saitoh   +2 more
openalex   +1 more source

Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases

Cell Proliferation, EarlyView.
HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang, Yue‐Yue Wang, Ri Wen, Tie‐Ning Zhang, Ni Yang   +4 more
wiley   +1 more source

Melatonin and Vitamins: A Promising Combination to Augment Conventional Anticancer Therapies. [PDF]

Nutrients
Talib WH, Sabri SM, Hadi RW, Prémusz V, Beregi T.   +4 more
europepmc   +1 more source

The timed infusion paradigm for melatonin delivery: What has it taught us about the melatonin signal, its reception, and the photoperiodic control of seasonal responses? [PDF]

, 1993
Timothy J. Badness, J.Bradley Powers, Michael H. Hastings, Eric L. Bittman, Bruce D. Goldman   +4 more
openalex   +1 more source

Autophagy in PE: Dispute, Role and Potential Target

Cell Proliferation, EarlyView.
Autophagy homeostasis serves as a central hub regulating vascular remodelling during pregnancy. It integrates maternal, genetic, and fetal factors; shapes the functions of immune cells (NK cells, macrophages, and T cells); restrains endothelial inflammatory responses (cytokines, endothelial cell, oxidative/ER stress, and protein aggregation); and ...
Miao Xu, Qi Wang, Fang Wang, Li Kang, Huijing Ma, Mengnan Li, Zhuanghui Hao, Zhengrui Li, Ji'an Liu, Xufeng Huang, Hengrui Liu, Shouxin Wei, Hailan Yang   +12 more
wiley   +1 more source

Dose-dependent effects of melatonin on berberine production, antioxidant activity, and metabolite profiles in Berberis vulgaris L. suspension cultures. [PDF]

Sci Rep
Zeidi SH, Sharifi M, Samari E, Ghanati F, Niknam V, Zhaleh N.   +5 more
europepmc   +1 more source