Results 11 to 20 of about 61,717 (309)

Melatonin Receptor Genes in Vertebrates [PDF]

International Journal of Molecular Sciences, 2013
Melatonin receptors are members of the G protein-coupled receptor (GPCR) family. Three genes for melatonin receptors have been cloned. The MT1 (or Mel1a or MTNR1A) and MT2 (or Mel1b or MTNR1B) receptor subtypes are present in humans and other mammals, while an additional melatonin receptor subtype, Mel1c (or MTNR1C), has been identified in fish ...
Di Li, David Smith, Rüdiger Hardeland, Ming Yang, Huai Xu, Long Zhang, Hua Yin, Qing Zhu   +7 more
openaire   +5 more sources

Melatonin receptor agonist protects against acute lung injury induced by ventilator through up-regulation of IL-10 production

Respiratory Research, 2020
Background It is well known that ventilation with high volume or pressure may damage healthy lungs or worsen injured lungs. Melatonin has been reported to be effective in animal models of acute lung injury.
Geng-Chin Wu, Chung-Kan Peng, Wen-I Liao, Hsin-Ping Pao, Kun-Lun Huang, Shi-Jye Chu   +5 more
doaj   +1 more source

Role of melatonin receptors in the effect of estrogen on brain edema, intracranial pressure and expression of aquaporin 4 after traumatic brain injury [PDF]

Iranian Journal of Basic Medical Sciences, 2018
Objective(s): Traumatic brain injury (TBI) is one of the most common causes of death and disability in modern societies. The role of steroids and melatonin is recognized as a neuroprotective factor in traumatic injuries.
Nader Shahrokhi, Mohammad khaksari, Gholamreza Asadikaram, Zahra soltani, Nava Shahrokhi   +4 more
doaj   +1 more source

A Review of Melatonin, Its Receptors and Drugs

Eurasian Journal of Medicine, 2019
After a Turkish scientist took Nobel Prize due to his contributions to understand clock genes, melatonin, closely related to these genes, may begin to shine.
Mucahit Emet, Halil Ozcan, Lutfu Ozel, Muhammed Yayla, Zekai Halici, Ahmet Hacimuftuoglu   +5 more
doaj   +1 more source

Peripheral and central mechanisms involved in hormonal control of male and female reproduction [PDF]

, 2016
Reproduction involves the integration of hormonal signals acting across multiple systems togenerate a synchronized physiological output. A critical component of reproduction is the luteinizinghormone (LH) surge, which is mediated by estradiol (E2) and ...
Bentley, G. E., Calandra, Ricardo Saul, Micevych, P. E., Paredes, A. H., Rudolph, L. M., Tesone, Marta, Wu, T. J.   +6 more
core   +1 more source

Preliminary Evaluation of Human Gingiva as an Extrapineal Site of Melatonin Biosynthesis in States of Periodontal Health and Disease [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Melatonin is a pineal gland hormone that plays an important role in periodontal homeostasis. Extra pineal melatonin production has been found to occur in tissues like the ovaries, retina and gastrointestinal tract.
Balaji Thodur Madapusi, Suresh Ranga Rao
doaj   +1 more source

Modeling the Heterodimer Interfaces of Melatonin Receptors

Frontiers in Cellular Neuroscience, 2021
Melatonin receptors are Class A G protein-coupled receptors (GPCRs) that regulate a plethora of physiological activities in response to the rhythmic secretion of melatonin from the pineal gland.
Lap Hang Tse, Yung Hou Wong, Yung Hou Wong, Yung Hou Wong   +3 more
doaj   +1 more source

Myopes have significantly higher serum melatonin concentrations than non-myopes [PDF]

, 2017
Purpose Experimental animal models of myopia demonstrate that higher melatonin (Mel) and lower dopamine (DA) concentrations actively promote axial elongation.
Ackermann, Atkinson, Ayaki, Baba, Barnard, Beck-Friis, Benavente-Pérez, Benloucif, Berg, Bertolet, Besharse, Breslin, Brown, Cahill, Chang, Chiba, Chua, Delgado, Dong, Eisenberg, Fan, Freedman, Guo, Hammond, He, Hua, Huang, Huang, Hughes, Iuvone, Jee, Kivelä, Lanyon, Logan, Lu, Mallen, Mao, Martin, McCullough, Megaw, Megaw, Nickla, Nickla, Ohngemach, Panda, Pendrak, Rada, Rao, Riefahn, Rohrer, Rose, Rudnicka, Sankaridurg, Skene, Stone, Stone, Stormann, Tosini, Trier, Verkicharla, Wahl, Wallman, Wang, Weiss, Wiechmann, Wiechmann, Wilson, Witkovsky, Wu, Xu, Zhang   +70 more
core   +2 more sources

Modulation of human ovarian function by melatonin

Frontiers in Bioscience-Elite, 2020
Melatonin, a hormone which is primarily released by the pineal gland, has a wide range of actions in the female reproductive tract. While the melatonin receptor subtype, MT3, has been identified in amphibian animals and birds, in humans and other mammals,
Seema Rai, Hindole Gosh
doaj   +1 more source

Clinical usefulness of melatonin MT1 and MT2 receptor agonists in the treatment of sleep disorders and depression

Medycyna Ogólna i Nauki o Zdrowiu, 2022
Introduction and objective Melatonin is the most important compound produced by the pineal gland. Its daily secretion cycle is responsible for the normal rhythm of sleep and wakefulness.
Sara Hmaidan, Ewa Gibuła-Tarłowska, Paweł Grochecki, Ewa Kędzierska   +3 more
doaj   +1 more source