Results 51 to 60 of about 61,717 (309)

Melatonin receptor expression in the zebra finch brain and peripheral tissues [PDF]

, 2012
The circadian endocrine hormone melatonin plays a significant role in many physiological processes such as modulating sleep/wake cycle and oxidative stress.
Brandstaetter, Roland, Helfer, Gisela, Jones, Catherine   +2 more
core   +1 more source

Fluorescent Nanosensor for Indole‐3‐Propionic Acid Detection in Gut Health Monitoring

Advanced Healthcare Materials, EarlyView.
This work introduces a fluorescent nanosensor system with two optical modalities for detection of indole‐3‐propionic acid (IPA) gut metabolite: (1) blue‐emitting cationic conjugated polyelectrolyte (CP3) and (2) near‐infrared (NIR)‐emitting CP3‐wrapped single‐walled carbon nanotube (SWNT).
Mervin Chun‐Yi Ang, Jonathan Wei Jie Lee, Sayyid Mohaideen, Gabriel Sánchez‐Velázquez, Song Wang, Yangyang Han, Liu Lin, Germaine Yong, Raju Cheerlavancha, Duc Thinh Khong, Jianhong Ching, Sharon Hong Yu Han, Jun Yu Yeo, Lian Xu, Gajendra Pratap Singh, Michael S. Strano   +15 more
wiley   +1 more source

The effect of melatonin on bacterial translocation following ischemia/reperfusion injury in a rat model of superior mesenteric artery occlusion [PDF]

, 2015
Background: Acute mesenteric ischemia is a life-threatening vascular emergency resulting in tissue destruction due to ischemia-reperfusion injury. Melatonin, the primary hormone of the pineal gland, is a powerful scavenger of reactive oxygen species (ROS)
Aydin, B., Aydin, C., Berber, I., Birsen, O., Cevahir, N., Gumrukcu, G., Yenisey, C., Özban, Murat.   +7 more
core   +2 more sources

Macrophage Membrane‐Cloaked, ROS‐Triggered Quercetin Nanocarriers Target Ovarian Lesions to Treat Polycystic Ovary Syndrome

Advanced Healthcare Materials, EarlyView.
The synthesis process of MM@PCD@QNPs and its potential mechanism for treating PCOS. (A) Assembly steps of MM@PCD@QNPs. (B) Synthesis and decomposition of MM@PCD@QNPs. (C) Potential therapeutic mechanisms of MM@PCD@QNPs for PCOS. PCD, PABP conjugated with DEX polymer; QUR, quercetin; CDI, N, N′‐carbonyldiimidazole; DEX, dextran; PABP, 4‐(hydroxymethyl ...
Wenzhu Li, Yu Guan, Nan Song, Feng Zhang, Zhimin Deng, Tailang Yin, Yanbing Yang, João Conde, Wenyi Jin, Zhinang Yin   +9 more
wiley   +1 more source

Characterization of central melatonin receptors using ¹²⁵I‐melatonin [PDF]

FEBS Letters, 1986
The binding of 125I‐melatonin, a potent analog of melatonin, to rat brain synaptosomal preparations was investigated. 125I‐melatonin bound with high affinity (K d = 38 nM) to a single class of sites (B max = 81 protein). Kinetic studies indicated that binding was time‐dependent and reversible. Specific 125I‐melatonin binding was inhibited by melatonin,
Laudon, Moshe, Zisapel, Nava
openaire   +2 more sources

Rapid Remodeling of the Human Gut Microbiome in Response to Short‐Term Animal Product Restriction and Associations with Host Molecular Phenotypes

Advanced Science, EarlyView.
A real‐world model of structured animal product restriction practiced for religious reasons reveals the dynamic adaptability of the human gut microbiome to dietary change and uncovers reductions in diversity and rare taxa loss. Integrated microbiome, metabolomic, and proteomic analyses uncover coordinated taxonomic and molecular shifts and identify ...
Christina Emmanouil, Maria Anezaki, Alexandros Simistiras, Stavros Glentis, Nikolaos Scarmeas, Pantelis Hatzis, Konstantinos Rouskas, Antigone S. Dimas   +7 more
wiley   +1 more source

Melatonin distribution reveals clues to its biological significance in basal metazoans.

PLoS ONE, 2012
Although nearly ubiquitous in nature, the precise biological significance of endogenous melatonin is poorly understood in phylogenetically basal taxa.
Modi Roopin, Oren Levy
doaj   +1 more source

Melatonin Improves Turbot Oocyte Meiotic Maturation and Antioxidant Capacity, Inhibits Apoptosis-Related Genes mRNAs In Vitro

Antioxidants, 2023
High-quality eggs are essential for the sustainability of commercial aquaculture production. Melatonin is a potent candidate for regulating the growth and maturation of oocytes.
Jiarong Zhang, Feixia Li, Xiaoyu Zhang, Ting Xie, Hongyu Qin, Junxian Lv, Yunhong Gao, Mingyue Li, Yuntao Gao, Yudong Jia   +9 more
doaj   +1 more source

Genetic disruption of the core circadian clock impairs hippocampus-dependent memory [PDF]

, 2014
Perturbing the circadian system by electrolytically lesioning the suprachiasmatic nucleus (SCN) or varying the environmental light:dark schedule impairs memory, suggesting that memory depends on the circadian system.
Chen, Xuanmao, Phan, Trongha X., Saraf, Amit, Storm, Daniel R., Wardlaw, Sarah M.   +4 more
core   +2 more sources

Plant‐Derived Melatonin Inhibits Bacterial Virulence via CpxA/R Two‐Component System

Advanced Science, EarlyView.
Plant‐derived melatonin is sensed by CpxAE48/T51, which inhibits the phosphorylation cascade transmission from CpxAH240 to CpxRD52, resulting in the inhibition of DNA‐binding capacity of CpxR and subsequent T3SS genes expression in Pst DC3000. ABSTRACT In defending against pathogens, plants deploy diverse secondary metabolites and signaling molecules ...
Jin‐Wei Wei, Wei Liu, Bili Cao, Dan Zhao, Chengqiang Wang, Xin Hou, Tangyuan Ning, Biao Gong   +7 more
wiley   +1 more source