Results 1 to 10 of about 25,767 (309)

Melatonin receptors and Per1 expression in the inferior olivary nucleus of the Sapajus apella monkey [PDF]

open access: yesFrontiers in Neuroscience, 2022
Melatonin is a transducer of photic environmental information and participates in the synchronization of various physiological and behavioral phenomena.
Marcos Donizete Junior Granado   +9 more
doaj   +2 more sources

Melatonin Receptors: A Key Mediator in Animal Reproduction [PDF]

open access: yesVeterinary Sciences, 2022
Melatonin, a hormone produced by the mammalian pineal gland, influences various physiological activities, many of which are related to animal reproduction, including neuroendocrine function, rhythm regulation, seasonal behavior, gonadogenesis, gamete ...
Yuan Gao   +3 more
doaj   +2 more sources

Modeling the Heterodimer Interfaces of Melatonin Receptors [PDF]

open access: yesFrontiers in Cellular Neuroscience, 2021
Melatonin receptors are Class A G protein-coupled receptors (GPCRs) that regulate a plethora of physiological activities in response to the rhythmic secretion of melatonin from the pineal gland.
Lap Hang Tse   +3 more
doaj   +2 more sources

The genomic response of human granulosa cells (KGN) to melatonin and specific agonists/antagonists to the melatonin receptors [PDF]

open access: yesScientific Reports, 2022
Melatonin is a known modulator of follicle development; it acts through several molecular cascades via binding to its two specific receptors MT1 and MT2. Even though it is believed that melatonin can modulate granulosa cell (GC) functions, there is still
Asma Arjoune, Marc-André Sirard
doaj   +2 more sources

Phylogenetic and Structural Insights into Melatonin Receptors in Plants: Case Study in Capsicum chinense Jacq [PDF]

open access: yesPlants
Recently, it has been proposed that plant melatonin receptors belong to the superfamily of G protein-coupled receptors (GPCRs). However, a detailed description of the phylogeny, protein structure, and binding properties of melatonin, which is still ...
Adrian Toledo-Castiñeira   +5 more
doaj   +2 more sources

Structural insights into melatonin receptors. [PDF]

open access: yesFEBS J, 2020
The long‐anticipated high‐resolution structures of the human melatonin G protein‐coupled receptors MT1 and MT2, involved in establishing and maintaining circadian rhythm, were obtained in complex with two melatonin analogs and two approved anti‐insomnia and antidepression drugs using X‐ray free‐electron laser serial femtosecond crystallography.
Stauch B, Johansson LC, Cherezov V.
europepmc   +4 more sources

Role of melatonin receptors in the effect of estrogen on brain edema, intracranial pressure and expression of aquaporin 4 after traumatic brain injury [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2018
Objective(s): Traumatic brain injury (TBI) is one of the most common causes of death and disability in modern societies. The role of steroids and melatonin is recognized as a neuroprotective factor in traumatic injuries.
Nader Shahrokhi   +4 more
doaj   +1 more source

Melatonin in Th17/Treg differentiation: the contribution of the hormone's own production by T lymphocytes

open access: yesМедицинская иммунология, 2023
The hormone melatonin is involved in regulation of functioning of almost all organs and systems of the organism. In the immune system, T lymphocytes are an important target of melatonin: they express specific melatonin receptors with different affinities
N. S. Glebezdina   +2 more
doaj   +1 more source

Melatonin and Its Homologs Induce Immune Responses via Receptors trP47363-trP13076 in Nicotiana benthamiana

open access: yesFrontiers in Plant Science, 2021
Melatonin (N-acetyl-5-methoxytryptamine), a naturally occurring small molecule, can protect plants against abiotic stress after exogenous treatmenting with it.
Mengmeng Kong   +8 more
doaj   +1 more source

Developmental effect of light deprivation on synaptic plasticity of rats' hippocampus: implications for melatonin [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2016
Objective(s): There are few reports have demonstrated the effect of a change-in-light experience on the structure and function of hippocampus. A change-in-light experience also affects the circadian pattern of melatonin secretion.
Sayyed Alireza Talaei   +2 more
doaj   +1 more source

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