Results 101 to 110 of about 25,767 (309)

From Tobacco to Ultraprocessed Food: How Industry Engineering Fuels the Epidemic of Preventable Disease

The Milbank Quarterly, EarlyView.
Policy Points Ultraprocessed foods (UPFs) are engineered to heighten reward and accelerate delivery of reinforcing ingredients, driving compulsive consumption and disrupting appetite regulation. This is a growing challenge for health policy. UPFs share key engineering strategies adopted from the tobacco industry, such as dose optimization and hedonic ...
ASHLEY N. GEARHARDT, KELLY D. BROWNELL, ALLAN M. BRANDT   +2 more
wiley   +1 more source

Design and Validation of the First Family of Photo-Activatable Ligands for Melatonin Receptors. [PDF]

J Med Chem, 2022
Somalo-Barranco G, Serra C, Lyons D, Piggins HD, Jockers R, Llebaria A.   +5 more
europepmc   +1 more source

Expression of Melatonin Receptor 1 in Rat Mesenteric Artery and Perivascular Adipose Tissue and Vasoactive Action of Melatonin [PDF]

, 2020
Ľuboš Molčan, Andreas Maier, Anna Zemančíková, Katharina Gelles, J Török, Michal Zeman, Isabella Ellinger   +6 more
openalex   +1 more source

Long-term environmental exposure of darkness induces hyperandrogenism in PCOS via melatonin receptor 1A and aromatase reduction [PDF]

, 2022
Weiwei Chu, Shang Li, Xueying Geng, Dongshuang Wang, Junyu Zhai, Gang Lü, Wai‐Yee Chan, Zi‐Jiang Chen, Yanzhi Du   +8 more
openalex   +1 more source

Extraocular Photoreception in Optic Lobes, Suckers, and Skin of Octopus vulgaris

Integrative Zoology, EarlyView.
Evidence of extra‐ocular photoreception in Octopus vulgaris (a) Diagram of the O. vulgaris different tissues considered: SPB, sucker proximal big; SPL, sucker proximal large; SM, sucker medium; SD, sucker distal; SK, skin; OL, optic lobes; RT, retina; (b‐d) Gene expression analysis of Ov‐GRK1 (red), Ov‐retinochrome (green), Ov‐rhodopsin (blue) mRNA ...
Valeria Maselli, Al‐Sayed Al‐Soudy, Mariangela Norcia, Stefania Galdiero, Sara Palladino, Emanuela Cirillo, Gianluca Polese, Anna Di Cosmo   +7 more
wiley   +1 more source

Pharmacological and Mechanistic Interventions for Cognitive Impairment Associated With Schizophrenia: A Review of Registered Clinical Trials

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background Schizophrenia is characterized by positive, negative, and cognitive symptoms. Current pharmacological treatments often fail to address cognitive deficits. In this review of clinical trials, we aim to identify studies that explore neurobiological (non‐psychological) strategies to address Cognitive Impairment Associated with ...
Bahareh Peyrovian, Lena Palaniyappan, Theodore T. Kolivakis, Howard C. Margolese   +3 more
wiley   +1 more source

Luminogenic HiBiT Peptide-Based NanoBRET Ligand Binding Assays for Melatonin Receptors. [PDF]

ACS Pharmacol Transl Sci, 2022
Gbahou F, Levin S, Tikhonova IG, Somalo Barranco G, Izabelle C, Ohana RF, Jockers R.   +6 more
europepmc   +1 more source

Polymorphisms of the melatonin receptor 1A (MTNR1A) gene affect sexual performance of Rasa Aragonesa rams without changing their social dominance [PDF]

, 2022
J.A. Abecia, Andrea L Heredia, V. Carcangiu, María Consuelo Mura, Genaro C. Miranda‐de la Lama   +4 more
openalex   +1 more source

Pain management after elective caesarean section under neuraxial anaesthesia: an updated systematic review and procedure‐specific postoperative pain management (PROSPECT) recommendations

Anaesthesia, EarlyView.
Summary Introduction Elective caesarean section is a common and painful procedure. Uncontrolled pain following caesarean section can profoundly and negatively on a wide range of patient and healthcare‐centred outcomes. The aim of this systematic review was to update existing recommendations for postoperative pain management after elective caesarean ...
Gillian Crowe, Benjamin Atterton, Eva Roofthooft, Girish P. Joshi, Narinder Rawal, Christopher Wu, Axel R. Sauter, Marie‐Pierre Bonnet, Dominique Nuala Lucas, Marc Van de Velde, on behalf of the PROSPECT Working Group of the European Society of Regional Anaesthesia and Pain Therapy, Henrik Kehlet, Stephan M. Freys, Dileep N. Lobo, Eleni Moka, Neel Desai, Dario Bugada, Patricia Lavand'Homme, Helene Beloeil, Johan Raeder, Esther M. Pogatzki‐Zahn, Eric Albrecht, Geertrui Dewinter   +22 more
wiley   +1 more source

Critical care delirium: prevention, identification and management: a narrative review

Anaesthesia, EarlyView.
Summary Introduction Delirium is a frequent complication of critical illness and remains an important cause of short‐ and long‐term morbidity for patients admitted to ICUs. Delirium is associated with prolonged mechanical ventilation; extended ICU and hospital stay; and longer‐term health issues. Development is associated with patient (e.g.
Stephanie Kieswick, Ben Gibbison
wiley   +1 more source