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Story behind meldonium–from pharmacology to performance enhancement: a narrative review

British Journal of Sports Medicine, 2016
Recent reports from the World Anti-Doping Agency (WADA) indicate an alarming prevalence in the use of meldonium among elite athletes. Therefore, in January 2016, meldonium was added to WADA's prohibited list after being monitored since 2015. Meldonium has been shown to have beneficial effects in cardiovascular, neurological and metabolic diseases due ...
Wolfgang, Schobersberger +3 more
openaire +2 more sources

UPLC‐MS/MS method for bioequivalence study of oral drugs of meldonium

Biomedical Chromatography, 2011
ABSTRACTA rapid and simple method based on ultra‐performance liquid chromatography on a hydrophilic interaction chromatography column with tandem mass‐selective detection (UPLC‐MS/MS) to determine meldonium in human plasma was developed. The calibration curve acquired in the range of 10–6000 ng/mL had quadratic form.
Yuriy V, Pidpruzhnykov +3 more
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Testing for Meldonium, a Doping Agent, in Human Hair

Drug Testing and Analysis
ABSTRACTMeldonium has been developed in the 70s in Latvia and is currently used in a limited number of countries for heart‐related diseases, such as heart attack, failure, or angina pectoris. Due to its metabolic properties (decrease of lactate production, increase of glycogen use, and protective action again oxidative stress), meldonium has been ...
Pascal Kintz, Jean‐Claude Alvarez, Laurie Gheddar +2 more
openaire +1 more source

Meldonium (Mildronate): A Performance‐Enhancing Drug?

Clinical Pharmacology in Drug Development, 2016
H Karl, Greenblatt, David J, Greenblatt
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Meldonium in milk and meat—An issue for professional athletes?