Results 51 to 60 of about 15,344 (194)

Metabolomic profiling of Burkholderia pseudomallei using UHPLC-ESI-Q-TOF-MS reveals specific biomarkers including 4-methyl-5-thiazoleethanol and unique thiamine degradation pathway [PDF]

, 2015
© 2015 Lau et al.Background: Burkholderia pseudomallei is an emerging pathogen that causes melioidosis, a serious and potentially fatal disease which requires prolonged antibiotics to prevent relapse.
Chow, WN, Curreem, SOT, Hui, SW, Lam, CW, Lau, CY, Lau, SKP, Lee, KC, Martelli, P, Sridhar, S, Wong, SCY, Woo, PCY, Yuen, KY   +11 more
core   +1 more source

Melioidosis

Current Opinion in Infectious Diseases, 2006
Melioidosis is increasingly recognized around the world. Despite several decades of clinical research, the mortality rate for melioidosis remains high. This review focuses on studies that relate to patient management, including risk factors, diagnosis, treatment and prediction of the outcome.
openaire   +2 more sources

A Coinfection Model of Leptospirosis and Melioidosis With Optimal Control

Journal of Applied Mathematics, Volume 2025, Issue 1, 2025.
Leptospirosis and melioidosis are emerging tropical diseases that are seriously affecting both human and animal populations worldwide. The actual incidence and fatal cases of the diseases are underreported due to a lack of awareness of the diseases, underuse of clinical microbiology laboratories test, and limitations of the model.
Habtamu Ayalew Engida, David Mwangi Theuri, Duncan Kioi Gathungu, John Gachohi, Haileyesus Tessema Alemneh, Keshlan S. Govinder   +5 more
wiley   +1 more source

Complete genome sequence of the encephalomyelitic Burkholderia pseudomallei strain MSHR305 [PDF]

, 2013
We describe the complete genome sequence of Burkholderia pseudomallei MSHR305, a clinical isolate taken from a fatal encephalomyelitis case, a rare form of melioidosis. This sequence will be used for comparisons to identify the genes that are involved in
Bruce, David C., Currie, Bart J., Detter, J. Chris, Gelhaus, H. Carl, Johnson, Shannon L., Keim, Paul, Mayo, Mark J., Stone, Joshua K., Tuanyok, Apichai   +8 more
core   +2 more sources

Misdiagnosing Melioidosis

Emerging Infectious Diseases, 2007
Melioidosis is endemic in southern and Southeast Asia and northern Australia. Although relatively few indigenous cases are recognized in the Indian subcontinent, a substantial proportion of cases imported into the United Kingdom originate there, probably reflecting patterns of immigration and travel, and underdiagnosis within the Indian subcontinent.
Brent, A, Matthews, P, Dance, D, Pitt, T, Handy, R   +4 more
openaire   +3 more sources

The Association Between Statin Therapy and the Subsequent Clinical Course of Patients With Melioidosis

Journal of Tropical Medicine, Volume 2025, Issue 1, 2025.
Background: Even in well‐resourced settings, the case‐fatality rate of melioidosis approaches 10%. This has prompted an interest in identifying adjunctive therapies that might improve survival. A prospective, multicentre study in Thailand suggested that statin therapy may reduce the incidence of pneumonia in patients with melioidosis; however, the ...
Laura Prideaux, Hayley Stratton, Meg Sandeman, Simon Smith, Josh Hanson, Lipi Buch   +5 more
wiley   +1 more source

Effect of temperature on Burkholderia pseudomallei growth, proteomic changes, motility and resistance to stress environments. [PDF]

, 2018
Burkholderia pseudomallei is a flagellated, gram-negative environmental bacterium that causes melioidosis, a severe infectious disease of humans and animals in tropical areas. We hypothesised that B.
Chantratita, Narisara, Paksanont, Suporn, Peacock, Sharon J, Pumirat, Pornpan, Sintiprungrat, Kitisak, Yimthin, Thatcha   +5 more
core   +1 more source

Melioidosis vaccines

Expert Review of Vaccines, 2002
Melioidosis is a disease caused by the facultative intracellular pathogen Burkholderia pseudomallei iand is associated with a high mortality rate. Melioidosis is endemic in the tropics of southeast Asia and northern Australia and is of worldwide concern, particularly as it is a potential agent of bioterrorism or biological warfare.
Jonathan, Warawa, Donald E, Woods
openaire   +2 more sources

Acanthamoeba castellanii–Mediated Reduction of Interleukin‐1β Secretion and Its Association With Macrophage Autophagy

Scientifica, Volume 2025, Issue 1, 2025.
Noncanonical autophagy including unconventional protein secretion has been extensively studied. Our work focused on a leaderless IL‐1β protein secretion from human macrophage in response to Acanthamoeba castellanii components, Acanthamoeba culture supernatant (CS) and cell lysate (CL), as well as its association with macrophage autophagy.
Rachasak Boonhok, Wilaiwan Senghoi, Suthinee Sangkanu, Chooi Ling Lim, Matsayapan Pudla, Maria de Lourdes Pereira, Polrat Wilairatana, Tooba Mahboob, Md. Atiar Rahman, Pongsak Utaisincharoen, Poonsit Hiransai, Veeranoot Nissapatorn, Simone Carradori   +12 more
wiley   +1 more source

Burkholderia pseudomallei Isolates from Sarawak, Malaysian Borneo, Are Predominantly Susceptible to Aminoglycosides and Macrolides [PDF]

, 2014
Melioidosis is a potentially fatal disease caused by the saprophytic bacterium Burkholderia pseudomallei. Resistance to gentamicin is generally a hallmark of B. pseudomallei, and gentamicin is a selective agent in media used for diagnosis of melioidosis.
Currie, Bart J., Fam, TemLom, Giffard, Philip M., Hii, KingChing, Kaestli, Mirjam, Keim, Paul, Mayo, Mark, Mohan, Anand, Ngian, HieUng, Ooi, MongHow, Podin, Yuwana, Price, Erin P., Sarovich, Derek S., Tuanyok, Apichai, Wong, IngTien, Wong, Jack, Wong, JinShyan, Wong, See-Chang   +17 more
core   +1 more source