Results 61 to 70 of about 6,424 (173)

The characteristics and clinical course of patients with melioidosis and cancer.

PLoS Neglected Tropical Diseases
BackgroundPatients with an active cancer are more likely to develop melioidosis, but the characteristics and clinical course of melioidosis in patients with cancer have not been examined in detail.
Tej Shukla, Simon Smith, Kristoffer Johnstone, Patrick Donald, Josh Hanson   +4 more
doaj   +1 more source

EMERGENCY PROPHYLAXIS OF EXPERIMENTAL MELIOIDOSIS USING SYNTHETIC IMMUNOMODULATORS AND HETEROLOGOUS VACCINES

RUDN Journal of Medicine, 2018
Melioidosis is a particularly dangerous infection caused by Burkholderia pseudomallei , against which a vaccine has not yet been created. In this regard, the development of effective treatment regimens and emergency prevention of melioidosis is very ...
I A Khabarova, S I Zhukova, K A Rotov, E A Snatenkov, A V Toporkov, D V Viktorov   +5 more
doaj   +1 more source

Melioidosis Presenting as Chronic Pneumonia With Soft Tissue Abscess in a Diabetic Patient Initially Treated for Tuberculosis: A Case Report From Vietnam

Respirology Case Reports, Volume 13, Issue 6, June 2025.
A 46‐year‐old diabetic Vietnamese engineer with soil exposure presented with chronic pneumonia and soft tissue abscess, initially misdiagnosed and treated for tuberculosis. Bronchoscopy culture revealed Burkholderia pseudomallei confirming melioidosis, and the patient achieved complete recovery with appropriate antibiotic therapy, highlighting the ...
Huy Quang Nguyen, Tra Thu Doan, Thanh Van Do, Cuong Duy Do, Vuong Minh Nong, Co Xuan Dao, Giap Van Vu   +6 more
wiley   +1 more source

Melioidosis: Clinical impact and public health threat in the tropics.

PLoS Neglected Tropical Diseases, 2017
This review briefly summarizes the geographical distribution and clinical impact of melioidosis, especially in the tropics. Burkholderia pseudomallei (a gram-negative bacterium) is the major causative agent for melioidosis, which is prevalent in ...
Ramar Perumal Samy, Bradley G Stiles, Gautam Sethi, Lina H K Lim   +3 more
doaj   +1 more source

Septicemic melioidosis complicating undiagnosed chronic kidney disease and beta-thalassemia minor in a Bangladeshi farmer

Saudi Journal of Kidney Diseases and Transplantation, 2020
Melioidosis is an emerging infectious disease in many countries including Bangladesh. Patients with diabetes mellitus are at increased risk for infection by Burkholderia pseudomallei, the causative agent for melioidosis.
Muhammad Abdur Rahim, Muhammad Abu Yousuf Khan, Tufayel Ahmed Chowdhury, Mehruba Alam Ananna   +3 more
doaj   +1 more source

Achieving Optimal Health With Host‐Directed Therapies (HDTs) in Infectious Diseases—A New Horizon

Advanced Therapeutics, Volume 8, Issue 4, April 2025.
Host‐directed therapies (HDTs) represent a transformative approach in infectious disease management by targeting host factors to enhance immune responses and inhibit viral replication. This innovative strategy leverages advanced genomics and gene editing technologies, offering promising avenues for improved patient outcomes and a new horizon in ...
Amol D. Gholap, Pankaj R. Khuspe, Sagar R. Pardeshi, Md Jasim Uddin, Ushasi Das, Navnath T. Hatvate, Satish Rojekar, Prabhanjan Giram, Mohammad Khalid, Yahya E. Choonara, Md. Faiyazuddin   +10 more
wiley   +1 more source

Clinical and Imaging Findings of Musculoskeletal Melioidosis in the Right Hip: A Case Report

대한영상의학회지, 2018
Melioidosis is an infectious disease caused by a Gram-negative bacterium thought to be caused Burkholderia pseudomallei. This disease is endemic in tropical regions, but is not endemic and is rarely encountered in Korea.
Myung Hyun Kim, Tong Jin Chun
doaj   +1 more source

Treatment of Melioidosis

Infectious Disease Clinics of North America
Melioidosis is caused by Burkholderia pseudomallei, a Gram-negative environmental saprophyte found in tropical and subtropical regions globally. The aims of treatment for melioidosis are to prevent death and other complications of septic shock, and to eradicate B. pseudomallei and prevent relapse. To achieve these aims, treatment comprises an intensive
Meumann, Ella M., Rajahram, Giri, Woolley, Stephen D., Smith, Simon, Gassiep, Ian   +4 more
openaire   +4 more sources

Burkholderia pseudomallei Sequence Type 46 Transmission from Asia to Australia

Emerging Infectious Diseases
Melioidosis is caused by the environmental pathogen Burkholderia pseudomallei. Among 1,331 patients with melioidosis during 1989–2023 in the Darwin Prospective Melioidosis Study in Australia, we identified 6 locally acquired cases caused by B ...
Ella M. Meumann, Mirjam Kaestli, Jessica R. Webb, Vanessa Rigas, Celeste Woerle, Mark Mayo, Bart J. Currie   +6 more
doaj   +1 more source

Exonic sequencing identifies TLR1 genetic variation associated with mortality in Thais with melioidosis

Emerging Microbes and Infections, 2019
Melioidosis, an infectious disease caused by the bacterium Burkholderia pseudomallei, is a common cause of sepsis in Southeast Asia. We investigated whether novel TLR1 coding variants are associated with outcome in Thai patients with melioidosis.
Shelton W. Wright, Mary J. Emond, Lara Lovelace-Macon, Deirdre Ducken, James Kashima, Viriya Hantrakun, Wirongrong Chierakul, Prapit Teparrukkul, Narisara Chantratita, Direk Limmathurotsakul, T. Eoin West   +10 more
doaj   +1 more source