Results 101 to 110 of about 15,825 (230)

Development of an immunotoxin incorporating the Australian jumper ant toxin, pilosulin 1 [PDF]

, 2007
University of Technology, Sydney. Faculty of Science.Immunotoxins are therapeutic agents that directly target toxins to specific cells and are generally comprised of an antibody or antibody fragment (Fab or scFv) linked to a toxic moiety.
Lemke, Susan Jane
core  

Isolation of Melittin from Iranian Honey Bee Venom and Investigation of Its Effect on Proliferation of Cervical Cancer- HeLa Cell Line

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2013
Introduction: Cervical cancer is the second prevalent cancer in developing countries and the sixth prevalent cancer in USA. Since conventional treatment methods are associated with detrimental side effects, searching for new drugs using natural ...
K Pooshang Bagheri, A Mahmoodzadeh, H Zarinnahad, M Mahdavi, D Shahbazzadeh, A Moradi   +5 more
doaj  

Outlook Magazine, Autumn 2013 [PDF]

, 2013
https://digitalcommons.wustl.edu/outlook/1190/thumbnail ...

core   +1 more source

Using zeta-potential measurements to quantify peptide partition to lipid membranes [PDF]

, 2011
© The Author(s) 2011. This article is published with open access at Springerlink.com.Open Access: This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and
Ana Salomé Veiga, AS Ladokhin, AV Delgado, B Kirby, C Alves, JF Miller, Joana Matos, João M. Freire, K Reddy, LD Mayer, M Castanho, M Kaszuba, Malvern, Manuel N. Melo, MARB Castanho, Marco M. Domingues, Miguel A. R. B. Castanho, MM Domingues, N Santos, N Santos, NC Santos, Nuno C. Santos, PM Matos, R Ferre, RE Hancock, RM Dawson, S Lopes, S Troeira Henriques, S White, SH White, W Tscharnuter   +30 more
core   +2 more sources

Kinetics and mechanism of hemolysis induced by melittin and by a synthetic melittin analogue

Biophysical Journal, 1982
The cytotoxic peptide from honeybee venom, melittin, and a synthetic peptide analogue of it lyse human erythrocytes in a biphasic process. The kinetics of the lysis in 0.30 M sucrose, 0.01 M sodium phosphate, pH 7.30 at 4 degrees C were investigated. Our results show that melittin rapidly binds to the outer surface of the erythrocyte membrane, and the ...
DeGrado, W.F., Musso, G.F., Lieber, M., Kaiser, E.T., Kézdy, F.J.   +4 more
openaire   +2 more sources

Effects of 1-butyl-3-methyl-imidazolium acetate on the solution behavior of melittin: A molecular dynamics study

Journal of Ionic Liquids
Ionic liquids posses efficiency as solvents, co-solvents or agents for applications involving biomolecules. Due to the increasing interest in systems containing proteins and ionic liquids, we hereby present results from molecular dynamics simulations on ...
Jessé Neumann, Hubert K. Stassen
doaj   +1 more source

Peptide-siRNA nanotherapeutics in arthritis [PDF]

, 2015
RNA interference (RNAi) is a process that involves the delivery of small single stranded RNA molecules into mammalian cells, resulting in the sequence-specific cleavage of complementary mRNA and the silencing of specific gene expression.
Pan, Hua, Pham, Christine T N, Wickline, Samuel A   +2 more
core   +3 more sources

How Melittin Inserts into Cell Membrane: Conformational Changes, Inter-Peptide Cooperation, and Disturbance on the Membrane

Molecules, 2019
Antimicrobial peptides (AMPs), as a key component of the immune defense systems of organisms, are a promising solution to the serious threat of drug-resistant bacteria to public health.
Jiajia Hong, Xuemei Lu, Zhixiong Deng, Shufeng Xiao, Bing Yuan, Kai Yang   +5 more
doaj   +1 more source

A molecular dynamics study of the bee venom melittin in aqueous solution, in methanol, and inserted in a phospholipid bilayer [PDF]

, 2018
The structural properties of melittin, a small amphipathic peptide found in the bee venom, are investigated in three different environments by molecular dynamics simulation.
Chandrasekhar, Indira, Glättli, Alice, Gunsteren, Wilfred   +2 more
core  

PHYSICO-CHEMICAL STUDIES OF APITOXIN AND PRODUCTS ON ITS BASIS

Фармация и фармакология (Пятигорск), 2018
Introduction. Nowadays, it is vitally important to develop a method for quantifying melittin not only in apitoxin samples, but also in the products of its processing.The aim of our study is to investigate physical and chemical characteristics of melittin,
L. I. Butenko, S. A. Kuleshova, J. V. Podgornaya, L. P. Myikots, A. B. Dmitriev   +4 more
doaj   +1 more source