Results 91 to 100 of about 11,509 (217)
Cancer NanotechnologyPurpose One intriguing therapy option for cancer is the peptide Melittin. This study assessed the in vitro anticancer effects of Melittin, Melittin-loaded pectin, and free pectin on mammary cell lines. Methods The “thin-layer hydration approach” produced
Esmaeil Alibeigi +4 more
doaj +1 more source
Molecular Simulations of Melittin-Induced Membrane Pores
, 2017 Membrane-active peptides (MAPs) are able to induce pores in cell membranes via molecular mechanisms, which are still subject to ongoing research. In this work, we present molecular dynamics simulations that suggest a precursor membrane defect plays an ...
Woodward, Clifford E. +9 more
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Advanced Healthcare Materials, Volume 15, Issue 30, 14 August 2026.Lymphotropic nanoplatforms integrate multimodal imaging with therapeutic guidance to map sentinel and tumor‐draining lymph nodes, revealing functional drainage, metastatic involvement, and nodal accessibility, while providing mechanistic insight to support precision surgical and therapeutic interventions.
Xu Chen +7 more
wiley +1 more source
Melittin induces ferroptosis and ER stress-CHOP-mediated apoptosis in A549 cells
, 2022 Melittin is a natural polypeptide present in bee venom, with significant anti-tumor activity. Melittin has been reported to induce cell death in lung carcinoma cell line A549 cells, suggesting an excellent potential for treating lung cancer. However, the
Bin Li (39349) +6 more
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Melittin: a Membrane-active Peptide with Diverse Functions
, 2006 Melittin is the principal toxic component in the venom of the European honey bee Apis mellifera and is a cationic, hemolytic peptide. It is a small linear peptide composed of 26 amino acid residues in which the amino-terminal region is predominantly ...
Chattopadhyay, Amitabha +3 more
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Structure-immunogenicity relationship of melittin, its transposed analogues, and D-melittin.
, 1994 Melittin, a 26-residue bee venom peptide, is known to induce murine Abs specific for its hydrophilic C-terminus of residues 20-26 and T cell responses specific for its hydrophobic mid-region of residue 11-19.
Wade D +5 more
core
Melittin-Induced Ca2+ (I) Increases and Subsequent Death in Canine Renal Tubular Cells
, 2011 The effect of melittin on cytosolic free Ca2+ concentration( [Ca2+](i)) and viability is largely unknown. This study examined whether melittin alters Ca2+ levels and causes Ca2+ -dependent cell death in Madin-Darby canine kidney (MDCK) cells.
劉絮穎;鄭賀雄;黃俊仁;張宏江;陳偉權;陳以書;許書雄;張宏泰;黃榮慶;陳錦時;盧逸超;簡崇仁 +1 more
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Does Dimeric Melittin Occur in Aqueous Solutions?
, 1985 Melittin, a peptide from bee venom, is known to undergo a monomer / tetramer conversion in aqueous solutions. We have studied the possible participation of dimers in the association equilibrium of melittin by sedimentation equilibrium experiments in the ...
Boss, K., Pappert, G., Schubert, D.
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, 2022 Triple-negative breast cancer (TNBC) is characterized by a high possibility of metastasis. M2-like tumor-associated macrophages (TAMs) are the main components of the tumor microenvironment (TME) and play a key role in TNBC metastasis. Therefore, TAMs may
Han, Ik-Hwan +7 more
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Restricted mobility of the sole tryptophan in membrane-bound melittin
, 1993 In spite of numerous studies, there appears to be no consensus regarding the orientation and aggregation state of membrane-bound melittin. We report here the restricted environment of the sole tryptophan residue in membrane-bound melittin using ...
Rukmini, R., Chattopadhyay, Amitabha
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