Results 91 to 100 of about 7,897 (182)

Melittin alcalase-hydrolysate: a novel chemically characterized multifunctional bioagent; antibacterial, anti-biofilm and anticancer

Frontiers in Microbiology
The prevalent life-threatening microbial and cancer diseases and lack of effective pharmaceutical therapies created the need for new molecules with antimicrobial and anticancer potential.
Samia E. El-Didamony, Mohamed H. Kalaba, Mohamed H. Sharaf, Esmail M. El-Fakharany, Esmail M. El-Fakharany, Esmail M. El-Fakharany, Ali Osman, Ali Osman, Ali Osman, Mahmoud Sitohy, Basel Sitohy, Basel Sitohy   +11 more
doaj   +1 more source

Potential Inhibitory Effect of the Peptide Melittin Purified from Apis mellifera Venom on CTX-M-Type Extended-Spectrum β-Lactamases of Escherichia coli

Antibiotics
Background. Extended-spectrum β-lactamases (ESBLs) hydrolyze nearly all β-lactam antibiotics, affecting one of the most important groups of antimicrobials used in Gram-negative infections. Among them, CTX-M is the most widespread type of ESBL. This study
Sheril Ramos-Alcántara, María Alejandra Cornejo Napan, Giovanni Lopez Campana, Jesus Tamariz   +3 more
doaj   +1 more source

Discovery of Melittin as Triple-Action Agent: Broad-Spectrum Antibacterial, Anti-Biofilm, and Potential Anti-Quorum Sensing Activities

Molecules
The development of antibiotic-resistant microorganisms is a major global health concern. Recently, there has been an increasing interest in antimicrobial peptides as a therapeutic option.
Hongyan Yang, Rong Ma, Jiarou Chen, Qian Xie, Wenhui Luo, Pinghua Sun, Zheng Liu, Jialiang Guo   +7 more
doaj   +1 more source

Nanocarrier-Enabled Melittin Therapy: Mechanistic Advances, Therapeutic Applications, and Translational Challenges. [PDF]

Int J Nanomedicine
Xiong Y, Cai H, Jia S, Gong B, Hou K, Wu H, Chen H.   +6 more
europepmc   +1 more source

From Toxin to Therapy: Biomedical Applications of Bee Venom in Cancer, Diabetes, and Neurodegenerative Disorders. [PDF]

Int J Mol Sci
Lourenço KA, Dos Santos MV, Araujo AC, Guiguer EL, Curi R, Rocha MG, Monteiro ES, Yanaguizawa Junior JL, Pithon-Curi T, Quesada K, de Abreu LC, Marcondes CO, Barbalho SM, Valenti VE, Miglino MA.   +14 more
europepmc   +1 more source

Melittin enhances PD-L1 blockade in prostate cancer by inhibiting M2 macrophage polarization and recruitment. [PDF]

World J Surg Oncol
Yan R, Zhang K, Chen J, Pan Y, Wang H.
europepmc   +1 more source

Erratum: [Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G₀/G₁ cell cycle arrest in esophageal carcinoma cells. [PDF]

Oncol Lett
Zhou C, Ma J, Lu Y, Zhao W, Xu B, Lin J, Ma Y, Tian Y, Zhang Q, Wang W, Yan W, Jiao P.   +11 more
europepmc   +1 more source

In Vitro Antitumor Effects of Melittin Attached to Fe₃O₄ Magnetic Nanoparticles with Synergistic Contribution of Magnetic Hyperthermia. [PDF]

Molecules
Câmpian A, Bâldea I, Muntean M, Iacoviță C, Florea A.   +4 more
europepmc   +1 more source

Bacterial cell fate under stress: lipid remodeling and antimicrobial peptide attack. [PDF]

NPJ Antimicrob Resist
Vejzovic D, Schwaiger T, Topciu A, Petrowitsch L, Arnautovic A, Malanovic N.   +5 more
europepmc   +1 more source

Melittin Acts as a Radiosensitizer for Non-Small Cell Lung Cancer by Inhibiting the DNA Damage Repair System and Inducing Apoptosis. [PDF]

Yonsei Med J
Seo E, Seo H, Kim KO, Lee KC.
europepmc   +1 more source