Results 81 to 90 of about 10,158 (214)

Melittin‐induced fusion of acidic liposomes [PDF]

FEBS Letters, 1983
Melittin‐induced fusion of acidic liposomes. Fusion was observed in the electron‐microscope and assayed as intermixing of both liposomes' contents and membranes. The melittin concentrations required for fusion induction were in the μM range compared to over 10 mM Ca2+ required for a comparable effect.
Eytan, Gera D., Almary, Taiser
openaire   +2 more sources

Administration of Apis cerana cerana melittin gene-encapsulated pectin for breast cancer therapy: an investigation of a new anti-cancer agent

Cancer Nanotechnology
Purpose One intriguing therapy option for cancer is the peptide Melittin. This study assessed the in vitro anticancer effects of Melittin, Melittin-loaded pectin, and free pectin on mammary cell lines. Methods The “thin-layer hydration approach” produced
Esmaeil Alibeigi, Arsham Azari Dehkordi, Milad Asadian, Abbas Doosti, Tohid Piri-Gharaghie   +4 more
doaj   +1 more source

Pyrazolyl–Pyridine Ruthenium Complexes: A New Metallic Line of Defense Against Acinetobacter baumannii

ChemBioChem, Volume 27, Issue 9, 14 May 2026.
Ruthenium(II) (Ru(II)) pyrazolyl–pyridine half‐sandwich complexes (C1–C6) were synthesized and structurally characterized as prospective metalloantibiotics. Screening through the Community for Open Antimicrobial Drug Discovery (CO‐ADD) revealed selective activity against Acinetobacter baumannii, with favorable cytotoxicity profiles. Biophysical studies
M. Cassiem Joseph, Sheldon Sookai, Monika Nowakowska, Rotondwa Mphephu, Angela M. Kavanagh, Johannes Zuegg, Mark A. T. Blaskovich, Andrew J. Swarts   +7 more
wiley   +1 more source

Aggregation state of melittin in lipid vesicle membranes

, 1991
We have performed time-resolved fluorescence energy transfer measurements using melittin as donor and a modified melittin as acceptor. The melittin molecules were bound to fluid vesicle membranes of dimyristoylphosphatidylcholine.
John, Edgar, Jähnig, Fritz
core   +1 more source

Isolating Melittin from Bee Venom and Evaluating its Effect on Proliferation of Gastric Cancer Cells

Basic & Clinical Cancer Research, 2013
Background : Gastric cancer (GC) is one of the most common cancers worldwide and in Iran. As conventional therapies such as surgery and chemotherapy are invasive with adverse effects, current studies are important as they are conducted to find natural ...
Amir Mahmoodzadeh, Ali Morady, Hannaneh Zarrinnahad, Kamran Pooshang Bagheri, Pooria Ghasemi-Dehkordi, Mahdi Mahdavi, Delavar Shahbazzadeh, Hamidreza Shahmorady   +7 more
doaj  

An ATP‐Mediated Antibiotic β‐Peptide Nanofiber That Kills Multidrug‐Resistant Bacteria via a Multistage Mechanism

Advanced Science, Volume 13, Issue 28, 18 May 2026.
The 3K‐AP system forms infinite supramolecular fibrils that undergo controlled degradation into shorter fragments upon enzymatic hydrolysis. Multitechnique imaging reveals a stepwise bacteriolytic mechanism involving bacterial entrapment, disassembly into lethal constructs, and associated extracellular vesicle release, highlighting the dynamic ...
Sohini Chakraborty, Kamal el Battioui, Dániel Molnár, Bálint Jezsó, Lejla Daruka, Tasvilla Sonallya, Tünde Juhász, Rita Hirmondó, Imola Cs. Szigyártó, Loránd Románszki, Natália Tőkési, Daniel Pinkas, Eszter Házy, Olivér Pavela, Andrea Bodor, Zoltán Varga, István Mándity, Mihály Kovács, Csaba Pál, Kata Horváti, Judit Tóth, Tamás Beke‐Somfai   +21 more
wiley   +1 more source

Process of Inducing Pores in Membranes by Melittin [PDF]

Biophysical Journal, 2013
Melittin is a prototype of the ubiquitous antimicrobial peptides that induce pores in membranes. It is commonly used as a molecular device for membrane permeabilization. Even at concentrations in the nanomolar range, melittin can induce transient pores that allow transmembrane conduction of atomic ions but not leakage of glucose or larger molecules. At
Lee, Ming-Tao, Sun, Tzu-Lin, Hung, Wei-Chin, Huang, Huey W.   +3 more
openaire   +3 more sources

A Perspective of Multi‐Reflecting TOF MS

Mass Spectrometry Reviews, Volume 45, Issue 3, Page 476-506, May/June 2026.
ABSTRACT Time‐of‐flight mass spectrometry (TOF MS) excels in rapid and high‐sensitivity analysis, making it a cornerstone of analytical chemistry. But as sample complexity explodes in omics studies, so does the need for higher resolving power to ensure accurate results.
A. N. Verenchikov, V. V. Makarov, A. V. Vorobyev, S. N. Kirillov   +3 more
wiley   +1 more source

Engineering Chondroitinase‐Free Baculovirus‐Insect Cell Expression System for Efficient Synthesis of Chondroitin Sulphates

Microbial Biotechnology, Volume 19, Issue 5, May 2026.
An engineered baculovirus‐insect cell platform produces chondroitinase‐free sulfotransferases, enabling efficient synthesis of chondroitin sulphates. ABSTRACT Owing to the high expression levels, proper protein folding and post‐translational modifications, baculovirus‐insect cell expression system is an ideal platform for producing active chondroitin ...
Junyue Li, Yuqing Tian, Lihe She, Zhangliang Liu, Yingying Zhou, Yanyan Wang, Jihui Zhang, Leilei Zhu, Huarong Tan, Jine Li   +9 more
wiley   +1 more source

Ultrafast polarized fluorescence measurements on monomeric and self-associated melittin [PDF]

, 2003
The anisotropic and magic-angle fluorescence decay of the single tryptophan (Trp) residue of melittin, a bee venom peptide, was investigated by time-resolved fluorescence anisotropy using a streak camera setup.
Grondelle, R. van, Kraayenhof, R., van Amerongen, H., van Grondelle, R., van Stokkum, I.H.M.; id_orcid, van Stokkum, I.H.M., Pandit, A., Stokkum, I.H.M. van, Amerongen, H. van, Larsen, O.F.A.   +9 more
core   +1 more source