Results 61 to 70 of about 10,158 (214)
Responsive Materials, EarlyView.Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan +8 more
wiley +1 more source
The effect of counterions on melittin aggregation [PDF]
Biochemical Journal, 1983 Melittin, a surface-active polypeptide from bee venom, has an overall hydrophobic N-terminus, with basic residues clustered at the C-terminus. In aqueous solution melittin exists as a mixture of monomer and tetramer, the monomer adopting a predominantly random-coil configuration, whereas the tetramer is rich in α-helix.
A S, Tatham, R C, Hider, A F, Drake
openaire +2 more sources
Melittin interaction with sulfated cell surface sugars
, 2008 Melittin is a 26-residue cationic peptide with cytolytic and antimicrobial properties. Studies on the action mechanism of melittin have focused almost exclusively on the membrane-perturbing properties of this peptide, investigating in detail the melittin-
Klocek, Gabriela, Seelig, Joachim
core +1 more source
Restricted mobility of the sole tryptophan in membrane-bound melittin [PDF]
, 1993 In spite of numerous studies, there appears to be no consensus regarding the orientation and aggregation state of membrane-bound melittin. We report here the restricted environment of the sole tryptophan residue in membrane-bound melittin using ...
Rukmini, R. +3 more
core +1 more source
Melittin as a safe compound to BALB/c mice immune system; a tiered approach immunotoxicity screening
BMC Complementary Medicine and Therapies, 2023 Background Maintenance of immune system integrity is a vital requirement to protect human body against pathogens/cancers. Natural compounds have long been used due to their benefits for the immune system. One of which is bee venom that contains a peptide
Gholamreza Karimi +7 more
doaj +1 more source
Effects of melittin on laying performance and intestinal barrier function of quails
Poultry Science, 2023 : To study the effects of melittin on egg-laying performance and intestinal barrier of quails, 240 quails (aged 70 d) were randomly divided into 4 groups with 6 replicates (10 quails per replicate). They were fed with basal diet (group B), basal diet + 0.
Zhili Li +6 more
doaj +1 more source
Multiplex Modular Nanorobotic Systems with Catalytic Activity under Magnetic Navigation
Advanced Functional Materials, Volume 36, Issue 48, 15 June 2026.We present modular nanorobots composed of a magnetic propulsion module and different extension modules carrying functional activities, assembled via DNA base pairing. The system integrates propulsion, optical tracking, enzymatic catalysis, and cell docking in a programmable manner.
Voichita Mihali +7 more
wiley +1 more source
Nature of Melittin-Phospholipid Interaction
Biophysical Journal, 1982 Melittin, the major protein component of bee venom that possesses a strong hemolytic activity (1), is an amphipathic protein whose amino acid residues 1-20 are predominantly hydrophobic; residues 21-26 are hydrophilic. Determination of the molecular basis and specificity of the attractive forces involved in its interaction with membranes is essential ...
Georghiou, S. +2 more
openaire +2 more sources
The structure of melittin [PDF]
European Journal of Biochemistry, 1988 The conformation of the 26‐residue polypeptide melittin has been studied using 1H‐NMR spectroscopy in methanolic solution. The 1H‐NMR spectrum of melittin has been assigned using two‐dimensional NMR techniques and the secondary structure has been calculated from nuclear Overhauser enhancement data using distance geometry and restrained molecular ...
Bazzo R. +5 more
openaire +3 more sources
Interaction of melittin with solid supported membranes
, 2000 The interaction of the membrane active peptide melittin with solid supported lipid bilayers has been scrutinized by means of impedance spectroscopy and scanning force microscopy. Highly flexible lipid bilayers anchored via a hydrophilic spacer terminated
Janshoff, Andreas +2 more
core +1 more source