Results 51 to 60 of about 11,509 (217)

Effects of melittin on laying performance and intestinal barrier function of quails

Poultry Science, 2023
: To study the effects of melittin on egg-laying performance and intestinal barrier of quails, 240 quails (aged 70 d) were randomly divided into 4 groups with 6 replicates (10 quails per replicate). They were fed with basal diet (group B), basal diet + 0.
Zhili Li, Rongxu Liu, Xuehan Wang, Haigang Wu, Xianguo Yi, Li Huang, Qingming Qin   +6 more
doaj   +1 more source

Proteo‐transcriptomic insights into the venom composition of the ectoparasitoid Eupelmus urozonus

Pest Management Science, EarlyView.
Integrated venom‐gland transcriptomics and venom proteomics of Eupelmus urozonus identified 316 venom proteins, including 75 secreted candidates, revealing diverse hydrolases, proteases/inhibitors and many uncharacterized effectors. Abstract BACKGROUND Ectoparasitoid venoms are ‘cocktails’ of bioactive molecules injected during oviposition to paralyze ...
Federica De Stefano, Carmen Scieuzo, Rosanna Salvia, Riccardo Moretti, Flora Cozzolino, Maria Monti, Heiko Vogel, Patrizia Falabella   +7 more
wiley   +1 more source

Melittin-Grafted HPMA-Oligolysine Based Copolymers for Gene Delivery

, 2013
Non-viral gene delivery systems capable of transfecting cells in the brain are critical in realizing the potential impact of nucleic acid therapeutics for diseases of the central nervous system.
Sellers, Drew L., Joan G. Schellinger, Chu, David S. H., Schellinger, Joan G., Philip J. Horner, Johnson, Russell N., David S.H. Chu, Stayton, Patrick S., Patrick S. Stayton, Don O. Maris, Convertine, Anthony J., Joshuel A. Pahang, Pahang, Joshuel A., Maris, Don O., Suzie H. Pun, Pun, Suzie H., Anthony J. Convertine, Drew L. Sellers, Horner, Philip J., Russell N. Johnson   +19 more
core   +1 more source

Survey of probable synergism between melittin and ciprofloxacin, rifampicin, and chloramphenicol against multidrug-resistant Pseudomonas aeruginosa

Frontiers in Microbiology
BackgroundThe emergence of multidrug-resistant bacteria and also biofilm-associated infections is a great health concern due to the failure of available antibiotics. This has alerted scientists to developing alternative antibiotics.
Mahsa Sedaghati, Reza Akbari, Lida Lotfollahi Hagghi, Saber Yousefi, Tahere Mesbahi, Mahdieh Delfi   +5 more
doaj   +1 more source

Melittin Reprograms Tumor‐Associated Macrophages Through CD18‐Mediated Immunomodulation

Phytotherapy Research, EarlyView.
Melittin selectively targets CD18 to deplete M2‐TAMs and remodel the TME to suppress tumor growth. ABSTRACT Tumor‐associated macrophages (TAMs), particularly the M2‐like subtype, contribute to an immunosuppressive tumor microenvironment and promote tumor progression.
Ik‐Hwan Han, Hyunju Lee, Eunbin Ko, Ilseob Choi, Soyoung Kim, Deok‐Sang Hwang, Hyunsu Bae   +6 more
wiley   +1 more source

The structure of melittin [PDF]

European Journal of Biochemistry, 1988
The conformation of the 26‐residue polypeptide melittin has been studied using 1H‐NMR spectroscopy in methanolic solution. The 1H‐NMR spectrum of melittin has been assigned using two‐dimensional NMR techniques and the secondary structure has been calculated from nuclear Overhauser enhancement data using distance geometry and restrained molecular ...
Bazzo R., Tappin M.J., Pastore A, Harvey T.S., Carver J.A., Campbell I.D.   +5 more
openaire   +3 more sources

Ultrafast polarized fluorescence measurements on monomeric and self-associated melittin [PDF]

, 2003
The anisotropic and magic-angle fluorescence decay of the single tryptophan (Trp) residue of melittin, a bee venom peptide, was investigated by time-resolved fluorescence anisotropy using a streak camera setup.
Kraayenhof, R., van Amerongen, H., van Grondelle, R., van Stokkum, I.H.M.; id_orcid, Pandit, A., Larsen, O.F.A.   +5 more
core   +1 more source

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

Phytotherapy Research, EarlyView.
Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li, Junnan Li, Guangzhi Li, Lili Huang, Tiantian Wen, Yanying Li, Yan Sun, Zhenqiang Liu, Qingshan Chen, Lili Zhang, Tiangang Lu, Ruiyan Wu, Haixue Kuang, Xiaochi Ma, Yan Liu   +14 more
wiley   +1 more source

Cholesterol inhibits the lytic activity of melittin in erythrocytes

, 2005
Although cell lysis by the hemolytic peptide, melittin, has been extensively studied, the role of specific lipids of the erythrocyte membrane on melittin-induced hemolysis remains unexplored.
Chattopadhyay, Amitabha, Raghuraman, H.
core   +1 more source

Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine

Phytotherapy Research, EarlyView.
By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao, Huiming Huang, Xuejiao Wei, Xiaoxue Wang, Wanying Xie, Xinyu Qiu, Fei Wang, Zhuguo Wang, Ruoxin Zhang, Yilin Cai, Changhai Qu, Zhongdong Hu   +11 more
wiley   +1 more source