Results 51 to 60 of about 10,158 (214)
Journal of Raman Spectroscopy, EarlyView.In this work, silver nanoparticles encapsulated within quatsome membranes have shown to preserve their plasmonic properties for at least 165 days without aggregation. These hybrid nanostructures enable strong SERS enhancement of pyrene and Prodan by confining the molecules within a few nanometers from the silver surface.
Renato Cezar Peramezza Ribeiro +10 more
wiley +1 more source
Improved nonviral gene vectors: Efficient and non-toxic polyplexes with enhanced endosomolytic activity [PDF]
, 2005 For the development of improved polyethylenimine (PEI) polyplexes towards ‘artificial viruses’ two key issues are i) to improve the toxicity profile of the applied vectors and ii) to enhance endosomal release, one of the major barriers to efficient gene ...
Boeckle, Sabine
core
Acyl Carrier Protein Interacts With Melittin
, 1990 Acyl carrier protein (ACP) from Escherichia coli has been shown to form complexes with melittin, a cationic peptide from bee venom. ACP is a small (Mr 8847), acidic, Ca2+-binding protein, which possesses some characteristics resembling those of ...
Ernst-Fonberg, Mary L. +2 more
core +1 more source
Antimicrobial Cyclic Peptidomimetics
Macromolecular Rapid Communications, EarlyView.Singular macromolecular cationic, amphipathic cyclic peptidomimetics with poly(2‐oxazoline)s‐esque backbone structure that undergo self‐assembly in water to form uniform nanoparticles were developed. The cyclic peptidomimetics, which act on bacterial cell membranes, exhibit hydrophobic‐dependent antimicrobial activity and toxicity.
Hao Luo, Edgar H. H. Wong
wiley +1 more source
Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives
Precision Medical Sciences, EarlyView.Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley +1 more source
Frontiers in MicrobiologyBackgroundThe emergence of multidrug-resistant bacteria and also biofilm-associated infections is a great health concern due to the failure of available antibiotics. This has alerted scientists to developing alternative antibiotics.
Mahsa Sedaghati +5 more
doaj +1 more source
Antimicrobial and antibiofilm effects of melittin and apamin bee venoms from apis mellifera l. on eskape pathogens and cytotoxic effects on l929 fibroblast cells [PDF]
Kafkas Universitesi Veteriner Fakültesi DergisiPublic health is facing a worldwide challenge due to the emergence of multiple antibiotic resistance in ESKAPE (Enterococcus faecalis, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Escherichia coli ...
Elif AYDIN +3 more
doaj +1 more source
Pore formation and translocation of melittin
Biophysical Journal, 1997 Melittin, a bee venom, is a basic amphiphilic peptide, which mainly acts on the lipid matrix of membranes, lysing various cells. To elucidate the molecular mechanism, we investigated its interactions with phospholipid vesicles. The peptide formed a pore with a short lifetime in the membrane, as revealed by the release of an anionic fluorescent dye ...
Matsuzaki, K. +2 more
openaire +2 more sources
Helical Structure of Recombinant Melittin
, 2019 Melittin is an extensively studied, 26-residue toxic peptide from honey bee venom. Because of its versatility in adopting a variety of secondary (helix or coil) and quaternary (monomer or tetramer) structures in various environments, melittin has been ...
Lisa S. Ramirez (6175997) +2 more
core +1 more source
Impact of Honeybee Venom Melittin on Cell Viability of Different Prostate Cancer Lineages
Креативная хирургия и онкология, 2022 Background. Melittin is a major constituent of honeybee venom and comprises a water-soluble surfactant peptide with cytolytic effects potentially applicable in anticancer therapy.
R. R. Khalikov +6 more
doaj +1 more source