Results 111 to 120 of about 10,158 (214)

A melittin mellrákra gyakorolt jótékony hatása

Szakdolgozatom célja, hogy bemutassam, hogy a méhméreg egyik legaktívabb komponense, a melittin, milyen szerepet játszhat az emlőrák elleni küzdelemben. A feldolgozott szakirodalmi források és a jelenlegi kutatási eredmények alapján megállapítható, hogy ...
Legány, Tünde
core  

Melittin modulates keratinocyte function through P2-receptor-dependent ADAM activation

, 2012
Melittin, the major component of the bee venom, is an amphipathic, cationic peptide with a wide spectrum of biological properties that is being considered as an anti-inflammatory and anti-cancer agent.
Bhakdi, Sucharit, Reiss, Karina, Sommer, Anselm, Andrä, Jörg, Speck, Nancy, Cornelsen, Isabell, Fries, Anja, Gimpl, Gerald, Koch-Nolte, Friedrich   +8 more
core   +1 more source

The presence of PEG-lipids in liposomes does not reduce melittin binding but decreases melittin-induced leakage

, 2002
Poly(ethyleneglycol) (PEG), anchored at the surface of liposomes via the conjugation to a lipid, is commonly used for increasing the liposome stability in the blood stream.
Lafleur, M, Rex, Sybille, Bian, J, Bian, Jiang, Rex, S, Silvius, John R., Lafleur, Michel, Silvius, JR   +7 more
core   +1 more source

Discovery of Melittin as Triple-Action Agent: Broad-Spectrum Antibacterial, Anti-Biofilm, and Potential Anti-Quorum Sensing Activities

Molecules
The development of antibiotic-resistant microorganisms is a major global health concern. Recently, there has been an increasing interest in antimicrobial peptides as a therapeutic option.
Hongyan Yang, Rong Ma, Jiarou Chen, Qian Xie, Wenhui Luo, Pinghua Sun, Zheng Liu, Jialiang Guo   +7 more
doaj   +1 more source

Melittin Adsorption and Lipid Monolayer Disruption at Liquid–Liquid Interfaces

, 2016
Melittin, a membrane-active peptide with antimicrobial activity, was investigated at the interface formed between two immiscible electrolyte solutions (ITIES) supported on a metallic electrode. Ion-transfer voltammetry showed well-defined semi-reversible
Manuel A. Méndez (1721857), Ibrahim Uyanik (2147659), Yu Lu (11575), Hubert H. Girault (1413781), Zahra Nazemi (2147656)   +4 more
core   +1 more source

Murine T cell responses to melittin and its analogs

, 1991
The 26-residue peptide melittin from bee venom elicits high IgG1 and IgE responses in selected strains of mice. The antibody responses were shown previously to be specific mainly for the region of residue 20-26.
Fehlner, P.F., King, T.P., Berg, R.H., Tam, J.P.   +3 more
core  

Melittin Aggregation in Aqueous Solutions: Insight from Molecular Dynamics Simulations

, 2016
Melittin is a natural peptide that aggregates in aqueous solutions with paradigmatic monomer-to-tetramer and coil-to-helix transitions. Since little is known about the molecular mechanisms of melittin aggregation in solution, we simulated its self ...
Severin T. Schneebeli (547859), Jonathan L. Slimovitch (1663882), Jun Zhao (59250), John C. Shelley (1663888), Chenyi Liao (1663876), Mee Shelley (1663885), Jianing Li (359834), Myvizhi Esai Selvan (1663879)   +7 more
core   +1 more source

Melittin-membran etkileşmelerinde steroidlerin rolü

, 2001
01.07.2001Melittin, arı zehirinden elde edilen küçük, toksik bir polipeptitdir. Toksik olması ve kanal yapıcı özelliğinden dolayı lipid/protein etkileşmelerini incelemede sıklıkla kullanılan model bir proteindir Steroidlerin membranların toksinlere karşı
Aksu, Soner, Severcan, Feride
core  

Nanocarrier-Enabled Melittin Therapy: Mechanistic Advances, Therapeutic Applications, and Translational Challenges. [PDF]

Int J Nanomedicine
Xiong Y, Cai H, Jia S, Gong B, Hou K, Wu H, Chen H.   +6 more
europepmc   +1 more source

From Toxin to Therapy: Biomedical Applications of Bee Venom in Cancer, Diabetes, and Neurodegenerative Disorders. [PDF]

Int J Mol Sci
Lourenço KA, Dos Santos MV, Araujo AC, Guiguer EL, Curi R, Rocha MG, Monteiro ES, Yanaguizawa Junior JL, Pithon-Curi T, Quesada K, de Abreu LC, Marcondes CO, Barbalho SM, Valenti VE, Miglino MA.   +14 more
europepmc   +1 more source