Results 131 to 140 of about 7,897 (182)
The Effect of Bee Venom and Melittin on Glioblastoma Cells in Zebrafish Model. [PDF]
Małek A, Strzemski M, Kurzepa J.
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High-Throughput Screening of FDA-Approved Drugs for Antibacterial and Antibiofilm Activities Against Multidrug-resistant <i>Pseudomonas aeruginosa</i>. [PDF]
Guo S +5 more
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Therapeutic effects of Melittin acupoint injection on rheumatoid arthritis through autophagy activation and PI3K/AKT/mTOR pathway inhibition. [PDF]
Xi W +11 more
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Melittin-phospholipid interaction Evidence for melittin aggregation
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1981Abstract The fluorescence spectra of the single tryptophan residue of melittin in 0.15 M potassium phosphate solution and when bound to egg phosphatidylcholine bilayer liposomes practically coincide and exhibit a large blue shift relative to that in aqueous solution.
S, Georghiou +2 more
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The interaction of calmodulin with melittin
Biochemical and Biophysical Research Communications, 1986Studies utilizing the interaction of melittin with the 1-106 fragment of calmodulin, the protection of calmodulin from tryptic digestion by melittin, and the interaction of the carbocyanine dye Stains-all with the calmodulin-melittin complex have indicated that complex formation of calmodulin with melittin involves the alpha-helical connecting bridge ...
C G, Caday, R F, Steiner
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Journal of Apitherapy, 2016
Cancer no longer is the automatic death sentence of centuries past, yet it remains a leading cause of global morbidity and mortality despite advances in detection, treatment, and survival in the field of oncology. The search for natural chemotherapeutic substances has accelerated research into the use of venom as a potential weapon against cancer.
Anna Tacn, PhD PhD
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Cancer no longer is the automatic death sentence of centuries past, yet it remains a leading cause of global morbidity and mortality despite advances in detection, treatment, and survival in the field of oncology. The search for natural chemotherapeutic substances has accelerated research into the use of venom as a potential weapon against cancer.
Anna Tacn, PhD PhD
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Quantifying the effects of melittin on liposomes
Melittin, the soluble peptide of bee venom, has been demonstrated to induce lysis of phospholipid liposomes. We have investigated the dependence of the lytic activity of melittin on lipid composition. The lysis of liposomes, measured by following their mass and dimensions when immobilised on a solid substrate, was close to zero when the negatively ...
Popplewell, J. F. +4 more
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Picosecond fluorescence spectrochronography of protein melittin and melittin-membrane complexes
Journal of Molecular Structure, 1990Abstract The results are presented of the study of protein melittin structure and dynamics when incorporated into the phospholipid bilayer carried out by time-resolved fluorescence spectroscopy with laser UV ps-pulse excitation.
A.Yu. Chikishev +3 more
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The actions of melittin on membranes
Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1990The molecular mechanisms underlying the various effects of melittin on membranes have not been completely defined and much of the evidence described indicates that different molecular mechanisms may underlie different actions of the peptide. Ideas about the formation of transbilayer aggregates of melittin under the influence of a transbilayer potential,
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Interactions of 2,2,2‐trifluoroethanol with melittin
Magnetic Resonance in Chemistry, 2009AbstractMelittin dissolved in 42% trifluoroethanol‐water at pH 2 has been shown to be α‐helical between residues 6 and 12 and between residues 13 and 25, with the two helical regions separated by a bend at the Leu13 residue. The inter‐helix angle was found to be 154 ± 3° at 0 °C and 135 ± 3° at 25 °C.
Robert C, Neuman, John T, Gerig
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