Results 111 to 120 of about 15,825 (230)

Melittin alleviates sepsis-induced acute kidney injury by promoting GPX4 expression to inhibit ferroptosis

Redox Report
Objectives: Melittin, the main component of bee venom, is a natural anti-inflammatory substance, in addition to its ability to fight cancer, antiviral, and useful in diabetes treatment.
Hongyan Zan, Jizheng Liu, Meixia Yang, Honghui Zhao, Chunyan Gao, Yunyan Dai, Zhiming Wang, Hongxuan Liu, Yunfei Zhang   +8 more
doaj   +1 more source

Melittin alcalase-hydrolysate: a novel chemically characterized multifunctional bioagent; antibacterial, anti-biofilm and anticancer

Frontiers in Microbiology
The prevalent life-threatening microbial and cancer diseases and lack of effective pharmaceutical therapies created the need for new molecules with antimicrobial and anticancer potential.
Samia E. El-Didamony, Mohamed H. Kalaba, Mohamed H. Sharaf, Esmail M. El-Fakharany, Esmail M. El-Fakharany, Esmail M. El-Fakharany, Ali Osman, Ali Osman, Ali Osman, Mahmoud Sitohy, Basel Sitohy, Basel Sitohy   +11 more
doaj   +1 more source

Effect of diet on the quality and quantity of venom produced by Apis cerana [PDF]

, 2016
The bee venom samples from honey bee (Apis cerana) foraged on seven plants dominating seven sites in Malaysia were collected. The protein content of the pollen loads of these test plants were tested according to the method of Kjeldahl (AOAC 1990).
Abusabbah, Mohammed, Lau, Wei Hong, M. Salih, Ashraf, Mahmoud, Mohammed E. E., Omar, Dzolkhifli   +4 more
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Polymer-based microfluidic device for measuring membrane protein activities [PDF]

, 2018
Functional assays of membrane proteins are becoming increasingly important, both in research and drug discovery applications. The majority of current assays use the patch-clamp technology to measure the activity of ion channels which are over-expressed ...
Hutter, I., Kresak, S., Kristiansen, P., Müller, E., Tiefenauer, L.   +4 more
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Discovery of Melittin as Triple-Action Agent: Broad-Spectrum Antibacterial, Anti-Biofilm, and Potential Anti-Quorum Sensing Activities

Molecules
The development of antibiotic-resistant microorganisms is a major global health concern. Recently, there has been an increasing interest in antimicrobial peptides as a therapeutic option.
Hongyan Yang, Rong Ma, Jiarou Chen, Qian Xie, Wenhui Luo, Pinghua Sun, Zheng Liu, Jialiang Guo   +7 more
doaj   +1 more source

Photoionization and excitation processes in proteins and peptides [PDF]

, 2018
Wij kijken naar moleculaire fragmentatiepatronen van peptiden en eiwitten en hun niet-dissociatieve ionisatie-opbrengsten als een functie van de moleculaire grootte en structuur.
Egorov, Dmitrii
core   +3 more sources

Calmodulin in Complex with Proteins and Small Molecule Ligands: Operating with the Element of Surprise. Implications for Structure-Based Drug Design [PDF]

, 2009
Calmodulin plays a role in several life processes, its flexibility allows binding of a number of different ligands from small molecules to amphiphilic peptide helices and proteins. Through the diversity of its functions, it is quite difficult to find new
Keserű, György Miklós, Menyhárd, D.K., Náray-Szabó, Gábor   +2 more
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Biomolecule surface patterning may enhance membrane association

, 2012
Under dehydration conditions, amphipathic Late Embryogenesis Abundant (LEA) proteins fold spontaneously from a random conformation into alpha-helical structures and this transition is promoted by the presence of membranes.
Browne J., Garay-Arroyo A., Gkeka P., Goyal K., Illya G., Nigel K. H. Slater, Panchal R. G., Pogodin S., Pogodin S., Pogodin S., Pogodin S., Popova A. V., Sergey Pogodin, Tolleter D., Tunnacliffe A., Vladimir A. Baulin, Wise M. J., Yang L.   +17 more
core   +1 more source

Melittin-Induced Structural Transformations in DMPG and DMPS Lipid Membranes: A Langmuir Monolayer and AFM Study

Molecules
In this study, we explore the interactions between melittin, a cationic antimicrobial peptide, and model lipid membranes composed of the negatively charged phospholipids 1,2-dimyristoyl-sn-glycero-3-phosphoglycerol (DMPG) and 1,2-dimyristoyl-sn-glycero-3-
Joanna Juhaniewicz-Debinska
doaj   +1 more source

Research on expression of HIV-1 env in baculovirus [PDF]

, 2000
昆虫细胞杆状病毒表达系统(BEVS)是真核表达系统的一种，以一种无需额外辅助的重组昆虫杆状病毒作为表达载体，目前已被应用来表达不同来源的基因，如细菌、病毒、植物和哺乳动物的基因。它具有表达产量高，蛋白经过完善的后处理过程，如内含子剪切、糖基化等特点。其原理是通过外源基因置换病毒的核多角体蛋白基因，使外源基因在核多角体蛋白启动子下高效表达。本论文中采用BEVS表达HIV-1包膜蛋白，目的在于弥补原核表达系统不能表达大片段的、高度糖基化的重组蛋白；并探索其应用在检测试剂中的前景。Baculovirus ...
郭庆
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