Results 11 to 20 of about 11,509 (217)
Comparative Determination of Melittin by Capillary Electrophoretic Methods
Journal of the Turkish Chemical Society, Section A: Chemistry, 2021 Bee venom from honey bees (Apis Mellifera L.) is known to have many pharmacological and biological properties. Melittin, a peptide consisting of 26 amino acids, is known as the main component of bee venom.
Melda AKAY +3 more
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The current landscape of the antimicrobial peptide melittin and its therapeutic potential [PDF]
Frontiers in ImmunologyMelittin, a main component of bee venom, is a cationic amphiphilic peptide with a linear α-helix structure. It has been reported that melittin can exert pharmacological effects, such as antitumor, antiviral and anti-inflammatory effects in vitro and in ...
Hai-Qian Zhang +3 more
doaj +2 more sources
A biomimetic nanoparticle-enabled toxoid vaccine against melittin
International Journal of Nanomedicine, 2018 Tianyi Kang,1 Chenyang Li,1,2 Ting Du,1 Yujiao Wu,1 Yuping Yang,1 Xuan Liu,1 Qianqian Zhang,1 Xiaoping Xu,3 Maling Gou1,4 1State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, People&rsquo ...
Kang T +8 more
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Interaction of melittin with endotoxic lipid A
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1992 Several amphipathic and cationic substances are known to bind lipid A, the toxic component of bacterial lipopolysaccharides. In this report, we have characterized, by fluorescence methods, the interaction of melittin, an amphipathic and basic 26-residue polypeptide isolated from bee venom, with lipid A.
David, SA +2 more
openaire +4 more sources
The membrane effects of melittin on gastric and colorectal cancer. [PDF]
PLoS ONE, 2019 The cytotoxic effects of melittin, a bee-venom peptide, have been widely studied towards cancer cells. Typically, these studies have examined the effect of melittin over extended-time courses (6-24 hours), meaning that immediate cellular interactions ...
Caroline Soliman +4 more
doaj +3 more sources
Multiple Membrane Interactions and Versatile Vesicle Deformations Elicited by Melittin
Toxins, 2013 Melittin induces various reactions in membranes and has been widely studied as a model for membrane-interacting peptide; however, the mechanism whereby melittin elicits its effects remains unclear. Here, we observed melittin-induced changes in individual
Kingo Takiguchi +5 more
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Synthesis and Evaluation of Melittin-Modified Peptides for Antibacterial Activity
ToxinsMelittin, a naturally occurring antimicrobial peptide, demonstrates broad-spectrum activity, effectively suppressing and eliminating both Gram-positive and Gram-negative bacteria, including specific drug-resistant strains.
Xiangxiang Xu +8 more
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Anionically-functionalized glycogen encapsulates melittin by multivalent interactions [PDF]
, 2022 We developed acid-functionalized glycogen conjugates as supramolecular carriers for efficient encapsulation and inhibition of a model cationic peptide melittin - the main component of honeybee venom.
Marcela, Filipová +12 more
core +1 more source
Iranian Journal of Parasitology, 2021 Background: Leishmaniasis is characterized by strong inflammatory responses with high levels of inflammatory cytokines that induce microRNA 21 and matrix metalloproteinases.
Soheila Akhzari +5 more
doaj +1 more source
Gold Nanoparticles Coated With the Antimicrobial Peptide Os-C(W5): Anticandidal and Biological Activity. [PDF]
J Pept SciGold nanoparticles conjugated with a tick‐derived antimicrobial peptide, Os‐C(W5), demonstrate enhanced proteolytic stability and potent antifungal activity against Candida albicans biofilms and planktonic cells. These non‐cytotoxic nanoconjugates represent a promising biocompatible strategy for combating resistant fungal infections while maintaining ...
Palm PJ +7 more
europepmc +2 more sources