Results 11 to 20 of about 25,852 (227)

Intravitreal melphalan for persistent retinoblastoma vitreous seeds

GMS Ophthalmology Cases, 2022
A 7-month-old male presented with bilateral retinoblastoma, initially group E OD and group C OS (International Intraocular Retinoblastoma Classification).
Redondo-Villanueva, Marie Jeazelle H., Mercado, Gary John V.   +1 more
doaj   +2 more sources

Intravitreal and Subconjunctival Melphalan for Retinoblastoma in Transgenic Mice [PDF]

Journal of Ophthalmology, 2014
Purpose. To measure the chemotherapeutic effects of focal melphalan (intravitreal and subconjunctival) on tumor burden, hypoxia, and vasculature in LHBETATAG murine retinoblastoma model. Methods. LHBETATAG transgenic mice were treated with a single 1 mcg
Nisha V. Shah, D. G. Pham, T. G. Murray, C. Decatur, E. Hernandez, Nikesh N. Shah, M. Cavalcante, S. K. Houston   +7 more
doaj   +2 more sources

Adding bendamustine to melphalan before ASCT improves CR rate in myeloma vs. melphalan alone: A randomized phase-2 trial. [PDF]

, 2022
Definite cure remains exceptional in myeloma patients even after high-dose chemotherapy (HDCT) with melphalan (Mel) and autologous stem cell transplantation (ASCT). Thus, improving efficacy of HDCT in MM remains an unresolved issue. This randomized phase
Zander, Thilo, Daskalakis, Michael, Schardt, Julian, Manz, Chantal, Legros, Myriam, Mansouri, Behrouz, Pabst, Thomas, Farag, Sarah, Jeker, Barbara, Rhyner, Gaelle, Lüthi, Jean-Marc, Bacher, Ulrike   +11 more
core   +1 more source

Case Report: Effectiveness of secukinumab in systemic sclerosis with early skin progress after autologous hematopoietic stem cell transplantation and end-stage kidney disease

Frontiers in Immunology, 2023
Autologous hematopoietic stem cell transplantation (aHSCT) represents an effective treatment option in patients with severe forms of systemic sclerosis (SSc) by resetting the immune system.
Patrick-Pascal Strunz, Hannah Labinsky, Lea-Kristin Nagler, Jan Portegys, Matthias Froehlich, Michael Gernert, Marc Schmalzing   +6 more
doaj   +1 more source

Comparison of Melphalan Combined with Treosulfan or Busulfan as High-Dose Chemotherapy before Autologous Stem Cell Transplantation in AML. [PDF]

, 2022
(1) Background: High-dose chemotherapy (HDCT) before autologous stem cell transplantation (ASCT) in acute myeloid leukemia (AML) patients predominantly combines busulfan with cyclophosphamide or melphalan.
Michael Hayoz, Aebi, Yolanda, Largiadèr, Carlo R, Pabst, Thomas, Yolanda Aebi, Thomas Pabst, Mansouri Taleghani, Behrouz, Ulrike Bacher, Hayoz, Michael, Ekaterina Gurevich, Gurevich, Ekaterina, Carlo R. Largiadèr, Bacher, Ulrike, Behrouz Mansouri Taleghani   +13 more
core   +1 more source

Modified dose of melphalan-prednisone in multiple myeloma patients receiving bortezomib plus melphalan-prednisone treatment [PDF]

The Korean Journal of Internal Medicine, 2019
Background/Aims Bortezomib plus melphalan-prednisone (VMP) is a standard treatment for multiple myeloma, particularly for patients who are ineligible for high-dose therapy. However, early discontinuation or treatment modification is often needed owing to
Se Ryeon Lee, Hojoon Choi, Byung Hyun Lee, Ka-Won Kang, Eun Sang Yu, Dae Sik Kim, Yong Park, Chul Won Choi, Byung Soo Kim, Hwa Jung Sung   +9 more
doaj   +1 more source

Isolated chemohyperthermal perfusion of the liver with melphalan in the treatment of unresectable liver metastases with uveal melanoma

Исследования и практика в медицине, 2021
Uveal melanoma belongs to rare malignant neoplasms, and the biological peculiarity of this tumor determines the high rate of distant metastasis, which reaches 60 %.
A. D. Kaprin, S. A. Ivanov, V. M. Unguryan, L. O. Petrov, E. A. Kruglov, Yu. A. Pobedintseva, E. V. Filimonov, A. G. Isaeva   +7 more
doaj   +1 more source

Isolated Limb Perfusion With Melphalan Triggers Immune Activation in Melanoma Patients

Frontiers in Oncology, 2018
Hyperthermic isolated limb perfusion with melphalan (M-ILP) is a treatment option for melanoma patients with metastases confined to the limbs. This study aimed at defining the role of cellular immunity for the clinical response to M-ILP in melanoma ...
Junko Johansson, Junko Johansson, Roberta Kiffin, Roberta Kiffin, Annica Andersson, Annica Andersson, Per Lindnér, Per Lindnér, Peter L. Naredi, Peter L. Naredi, Roger Olofsson Bagge, Roger Olofsson Bagge, Anna Martner, Anna Martner   +13 more
doaj   +1 more source

The Role of Autologous Hematopoietic Stem Cell Transplantation in the Therapy of Systemic AL Amyloidosis

Клиническая онкогематология, 2023
Aim. To assess the outcomes of autologous hematopoietic stem cell transplantation (auto-HSCT) in systemic AL Amyloidosis patients treated at the R.M.
Olga Vladislavovna Pirogova, O. V. Kudyasheva, A. G. Smirnova, V. V. Porunova, S. V. Tolstova, K. R. Kalimulina, M. V. Chernous, Yu. Yu. Vlasova, I. S. Moiseev, V. A. Dobronravov, A. D. Kulagin   +10 more
doaj   +1 more source

Investigation of characterization and cytotoxic effect of PEGylated nanoliposomal containing Melphalan on ovarian cancer: an in vitro study

Journal of Experimental Nanoscience, 2021
This study aimed to synthesize Melphalan (MEL)-loaded PEGylated nanoliposomes and evaluate their cytotoxic effects on ovarian cancer A2780CP and SKOV3 cells.
Seyedeh Masoomeh Sadat Mirnezami, Amir Heydarinasab, Azim Akbarzadeh, Mehdi Arjmand   +3 more
doaj   +1 more source