Results 51 to 60 of about 58,184 (319)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The effect of phosphorus on the iron redox ratio, viscosity, and density of an evolved ferro-basalt [PDF]
, 1994 Despite the abundant evidence for the enrichment of phosphorus during the petrogenesis of natural ferro-basalts, the effect of phosphorus on the physical properties of these melts is poorly understood.
Toplis, Michael J. +2 more
core +1 more source
Tectonomagmatic setting of the Siahbaz A-type granitoids and mafic intrusions (Northwest of Khoy [PDF]
پترولوژی, 2017 The Siahbaz granite-gabbro-appinite outcrops from the Northwest Khoy is related to one of the complex of the Late Ordovician-Early Permian. The complex is located on the north Sanandaj-Sirjan Zone.
Abdolnaser Fazlnia
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
General Trends in the Compression of Glasses and Liquids
CrystalsThe present work relates the isothermal volumes of silicate glasses and melts to the combined ionic volumes of their chemical constituents. The relation is an extension of a relation that has already been established for crystalline oxides, silicates ...
Oliver Tschauner
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Structural relaxation in silicate melts and non-Newtonian melt rheology in geologic processes [PDF]
, 1989 The timescale of structural relaxation in a silicate melt defines the transition from liquid (relaxed) to glassy (unrelaxed) behavior. Structural relaxation in silicate melts can be described by a relaxation time, , consistent with the observation that ...
Dingwell, Donald B., Webb, Sharon L.
core +1 more source
Tectonic Tenon transplants for four different corneal melts
Indian Journal of Ophthalmology. Case Reports, 2022 Tenon's tissue with good tensile strength, pliability, and availability is a valuable patch graft resource for small corneal perforations. We have extended its tectonic use to other corneal melts and leaks with anatomic success. Tenon's patch graft (TPG)
Radhika Natarajan, Nimisha Nagpal
doaj +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Data supporting "The C36 Laves phase in diblock polymer melts"
, 2021 Input and output files necessary to produce all of the results presented in the paper "The C36 Laves phase in diblock polymer melts." The Polymer Self-Consistent Field (PSCF) software package was used exclusively to generate these results.NSF Grant DMR ...
Magruder, Benjamin R, Dorfman, Kevin D
core +1 more source