Results 61 to 70 of about 23,537 (218)
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Oldest Immiscible Silica‐rich Melt on the Moon Recorded in a ~4.38 Ga Zircon
The temporal duration of lunar‐evolved magmatism is still poorly constrained. In lunar meteorite Northwest Africa (NWA) 10049, a melt inclusion‐bearing zircon fragment provides a new tool to understand the composition and age of the melts from which ...
Xiaojia Zeng +9 more
doaj +1 more source
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Formation of Structurally Bound Carbonate in Silicate Melts on the Top of the Mantle Transition Zone
Carbon‐bearing dense silicate melts may account for the seismically weak layers on top of the mantle transition zone (MTZ) at 13–14 GPa. How carbon is incorporated into silicate melts at such high pressures has not been experimentally probed, making the ...
Eun Jeong Kim, Sung Keun Lee
doaj +1 more source
VISCOSITY OF CuPb, CuPbSn, CuPbSnGa AND CuPbSnGaBi MELTS OF EQUIATOMIC COMPOSITIONS
We investigated the viscosity of CuPb, CuPbSn, CuPbSnGa and CuPbSnGaBi melts of equiatomic compositions by the method of damped torsion vibrations of a crucible. We saw the melts of equiatomic composition as the melts high-entropy.
Olga Chikova +2 more
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Effect of terahertz irradiation on DNA damage repair in living cells
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Satellite altimetry and gravimetry show that the Greenland ice sheet has been losing volume and mass since the beginning of this century. However, from these short time series of direct measurements we cannot infer what the causes of the mass loss are, i.
van den Broeke M.R.
doaj +1 more source
Copper and diamond content of the northern part of the Volyn-Podolskaya plate
Estimation of chemical parameters of the medium has been done, under which ore manifestations of native copper of the Volyno-Podolian plate (VPP) could be formed.
O. V. Usenko
doaj +1 more source

