Results 111 to 120 of about 34,274 (165)

Randomized Placebo-Controlled Trial of Memantine for Smoking Cessation (CCCWFU 99311)

Cancer Control
Introduction Quitting smoking is challenging even with existing pharmacotherapy. Thus, discovery of new cessation medications is imperative. Memantine, a well-tolerated Alzheimer’s disease drug, partially antagonizes glutamate at the N-methyl-D-Aspartate
John Spangler MD, Elizabeth Skidmore MD, Emily V. Dressler PhD, Kathryn E. Weaver PhD, Glenn J. Lesser MD, Gary Burton MD, Benjamin Esparaz MD, Brooke Gillett DO, Edward G. Shaw MD, MA   +8 more
doaj   +1 more source

The Level of NMDA Receptor in the Membrane Modulates Amyloid-β Association and Perforation [PDF]

, 2016
Alzheimer’s disease is a neurodegenerative disorder that affects mostly the elderly. The main histopathological markers are the senile plaques formed by amyloid-β peptide (Aβ) aggregates that can perforate the plasma membrane of cells, increasing the ...
Aguayo, Luis G, Fernández-Pérez, Eduardo, Peoples, Robert W., Peters, Christian, Sepúlveda, Fernando J.   +4 more
core   +1 more source

Effect of Memantine on Positive Sign in Patients with Schizophrenia and Schizoaffective Disorders: A Randomized Double Blind Placebo Controlled Trial

Journal of Mazandaran University of Medical Sciences, 2019
Background and purpose: Memantine is a medication used to treat moderate to severe Alzheimer’s disease. Memantine targeting the glutamatergic system specifically N-Methyl-D-Aspartate offer a novel approach in treatment of psychiatric disorders such as ...
Hamide Abbaspour kasgari, Maria Tavakoli Ardakani, Abdollah Farhadinasab   +2 more
doaj  

Memantine versus Methylphenidate in Children and Adolescents with Attention Deficit Hyperactivity Disorder: A Double-Blind, Randomized Clinical Trial

Iranian Journal of Psychiatry, 2016
Objectives: The aim of this randomized clinical trial was to assess the efficacy of memantine versus methylphenidate in the treatment of children with attention deficit hyperactivity disorder.
MohammadReza Mohammadi, Soleiman Mohammadzadeh, Shahin Akhondzadeh   +2 more
doaj  

Crocin Mitigates Glutamate Excitotoxicity and Tau Hyperphosphorylation by Modulating EAAT2 and Akt/Tau Pathway in a Scopolamine-induced Rat Model of Alzheimer's Disease. [PDF]

Neurochem Res
El-Baga SE, Hassan MH, Awadalla EA, Abd El-Kader AEM.   +3 more
europepmc   +1 more source

Neuroprotective effects of curcumin, memantine, and caffeic acid in a Rat model of cerebral ischemia-reperfusion injury. [PDF]

Front Pharmacol
Cakir CO, Yumuşak N, Tekeli MY, Bayram D, Cakir Bayram L, Baloğlu M.   +5 more
europepmc   +1 more source

Memantine to preserve memory and neurocognition following craniospinal irradiation (MEMENTO): a phase 3 randomized controlled trial. [PDF]

BMC Cancer
Gupta T, Dasgupta A, Goswami S, Chatterjee A, Dhingra S, Deodhar J, Sonkusare L, Prasad M, Gollamudi VRM, Kannan S, Vishwakarma K, Menon N, Moiyadi A, Shetty P, Singh V, Epari S, Sahay A, Shah A, Sahu A, Choudhari A, Bhattacharya K, Bano N, Gupta N, Chinnaswamy G.   +23 more
europepmc   +1 more source

Memantine for the treatment of obsessive-compulsive disorder: a systematic review and narrative synthesis. [PDF]

BMC Psychiatry
Bryan JW, Hassoulas A.
europepmc   +1 more source

NCATS Proposal – ALS Patients Demand [PDF]

, 2020
Barohn, Richard J., Statland, Jeffrey M.
core   +2 more sources

Neuroprotective properties of <i>Linzia gerberiformis</i> aqueous leaves extract against aluminium chloride (AlCl₃) -induced cognitive impairment: Involvement of cholinergic, GABAergic, and antioxidant mechanisms. [PDF]

IBRO Neurosci Rep
Noubouwo JC, Ngoupaye GT, Ngoufack SBK, Kom BTD, Foutsop AF, Adassi BM, Gnoupa KG, Yassi FB.   +7 more
europepmc   +1 more source