Results 31 to 40 of about 165,835 (261)
Intrinsically Disordered Proteins Drive Membrane Curvature [PDF]
Biophysical Journal, 2015 Abstract Assembly of highly curved membrane structures is essential to cellular physiology. The prevailing view has been that proteins with curvature-promoting structural motifs, such as wedge-like amphipathic helices and crescent-shaped BAR domains, are required for bending membranes.
Busch, David J. +5 more
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Revealing the Effects of Nanoscale Membrane Curvature on Lipid Mobility
Membranes, 2017 Recent advances in nanoengineering and super-resolution microscopy have enabled new capabilities for creating and observing membrane curvature. However, the effects of curvature on single-lipid diffusion have yet to be revealed. The simulations presented
Abir Maarouf Kabbani +2 more
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Influenza A matrix protein M1 induces lipid membrane deformation via protein multimerization [PDF]
, 2019 The matrix protein M1 of the Influenza A virus (IAV) is supposed to mediate viral assembly and budding at the plasma membrane (PM) of infected cells. In order for a new viral particle to form, the PM lipid bilayer has to bend into a vesicle toward the ...
Chiantia, Salvatore +2 more
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Membrane Curvature Sensing by Amphipathic Helices Is Modulated by the Surrounding Protein Backbone. [PDF]
PLoS ONE, 2015 Membrane curvature is involved in numerous biological pathways like vesicle trafficking, endocytosis or nuclear pore complex assembly. In addition to its topological role, membrane curvature is sensed by specific proteins, enabling the coordination of ...
Christine M Doucet +3 more
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Frontiers in Cell and Developmental Biology, 2023 The plasma membrane of mammalian cells links transmembrane receptors, various structural components, and membrane-binding proteins to subcellular processes, allowing inter- and intracellular communication.
Dmytro Puchkov +3 more
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Communicative & Integrative Biology, 2018 Membrane curvature is a property of biological membranes essential for organelle morphology and the formation of tubulovesicular carriers. Curvature generation is influenced by the lipid composition of the membrane and protein-mediated processes.
Takashi Hirama, Gregory D. Fairn
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Protein-Induced Membrane Curvature Alters Local Membrane Tension [PDF]
Biophysical Journal, 2014 Adsorption of proteins onto membranes can alter the local membrane curvature. This phenomenon has been observed in biological processes such as endocytosis, tubulation, and vesiculation. However, it is not clear how the local surface properties of the membrane, such as membrane tension, change in response to protein adsorption. In this article, we show
Rangamani, Padmini +2 more
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Role of disclinations in determining the morphology of deformable fluid interfaces [PDF]
, 2012 We study the equilibrium shapes of vesicles, with an in-plane nematic order, using a Monte-Carlo scheme and show that highly curved shapes, like tubes and discs, with a striking similarity to the structures engendered by certain curvature sensing ...
Ayton +31 more
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Alterations of membrane curvature during influenza virus budding [PDF]
, 2014 Influenza A virus belongs to the Orthomyxoviridae family. It is an enveloped virus that contains a segmented and negative-sense RNA genome. Influenza A viruses cause annual epidemics and occasional major pandemics, are a major cause of morbidity and ...
Agnieszka Martyna +29 more
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Membrane curvature sorts lipids [PDF]
EMBO reports, 2005 The enrichment of sphingolipids and cholesterol in the mammalian plasma membrane, and unsaturated phosphatidylcholine (PC) in the endoplasmic reticulum, requires lipid sorting in the Golgi apparatus. Most sphingolipids are synthesized in the Golgi lumen (Holthuis & Levine, 2005).
van Meer, G., Vaz, W.L.C.
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