Results 251 to 260 of about 840,592 (294)
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SNARE-mediated membrane fusion
Nature Reviews Molecular Cell Biology, 2001SNARE proteins have been proposed to mediate all intracellular membrane fusion events. There are over 30 SNARE family members in mammalian cells and each is found in a distinct subcellular compartment. It is likely that SNAREs encode aspects of membrane transport specificity but the mechanism by which this specificity is achieved remains controversial.
Y A, Chen, R H, Scheller
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Advanced Drug Delivery Reviews, 1999
Although catalyzed by different proteins, the energy barriers for lipid bilayer fusion in exocytosis, viral fusion, and trafficking seem to be the same as those for the fusion of protein-free phospholipid membranes. To minimize this energy, fusion will proceed through a minimal number of lipid molecules, probably localized in bent non-bilayer ...
, Zimmerberg, , Chernomordik
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Although catalyzed by different proteins, the energy barriers for lipid bilayer fusion in exocytosis, viral fusion, and trafficking seem to be the same as those for the fusion of protein-free phospholipid membranes. To minimize this energy, fusion will proceed through a minimal number of lipid molecules, probably localized in bent non-bilayer ...
, Zimmerberg, , Chernomordik
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Science, 1992
Common themes are emerging from the study of viral, cell-cell, intracellular, and liposome fusion. Viral and cellular membrane fusion events are mediated by fusion proteins or fusion machines. Viral fusion proteins share important characteristics, notably a fusion peptide within a transmembrane-anchored polypeptide chain.
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Common themes are emerging from the study of viral, cell-cell, intracellular, and liposome fusion. Viral and cellular membrane fusion events are mediated by fusion proteins or fusion machines. Viral fusion proteins share important characteristics, notably a fusion peptide within a transmembrane-anchored polypeptide chain.
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Experientia, 1990
The factors involved in the regulation of biological membrane fusion and models proposed for the molecular mechanism of biomembrane fusion are reviewed. The results obtained in model systems are critically discussed in the light of the known properties of biomembranes and characteristics of biomembrane fusion.
K N, Burger, A J, Verkleij
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The factors involved in the regulation of biological membrane fusion and models proposed for the molecular mechanism of biomembrane fusion are reviewed. The results obtained in model systems are critically discussed in the light of the known properties of biomembranes and characteristics of biomembrane fusion.
K N, Burger, A J, Verkleij
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Trends in Biochemical Sciences, 1991
Protein trafficking and membrane assembly are accomplished in eukaryotes by the specific targeting and fusion of vesicles. In this review we describe some of the molecules implicated as components of the fusion apparatus, and evidence that suggests the same factors are recruited for a variety of intracellular fusion events.
D W, Wilson +3 more
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Protein trafficking and membrane assembly are accomplished in eukaryotes by the specific targeting and fusion of vesicles. In this review we describe some of the molecules implicated as components of the fusion apparatus, and evidence that suggests the same factors are recruited for a variety of intracellular fusion events.
D W, Wilson +3 more
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Current Opinion in Cell Biology, 1989
One of the most intriguing properties of cellular membranes is their ability to fuse with one another. Within a living cell numerous membrane fusion and fission events occur, mediating the flow of cellular constituents between different cell organelles. How do two adhering membranes achieve this complex merging operation within the restriction posed by
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One of the most intriguing properties of cellular membranes is their ability to fuse with one another. Within a living cell numerous membrane fusion and fission events occur, mediating the flow of cellular constituents between different cell organelles. How do two adhering membranes achieve this complex merging operation within the restriction posed by
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Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology, 2012
The process of membrane fusion in the case of lipid bilayers, as well as induced by influenza virus is reviewed shortly. The methods of studying fusion kinetics in pure lipid and lipid-protein systems are described. The main theories of molecular fusion machines are presented. Open questions and unsolved problems are discussed in details. In conclusion,
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The process of membrane fusion in the case of lipid bilayers, as well as induced by influenza virus is reviewed shortly. The methods of studying fusion kinetics in pure lipid and lipid-protein systems are described. The main theories of molecular fusion machines are presented. Open questions and unsolved problems are discussed in details. In conclusion,
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Comprehensive Physiology, 1996
Abstract The sections in this article are: Observation of Fusion Requires Physical Techniques for Monitoring Mixing of Membranes and the Compartments they Enclose Morphological Changes Following Fusion Are Observed by Light Microscopy but Membrane Fusion
R. Blumenthal, D. S. Dimitrov
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Abstract The sections in this article are: Observation of Fusion Requires Physical Techniques for Monitoring Mixing of Membranes and the Compartments they Enclose Morphological Changes Following Fusion Are Observed by Light Microscopy but Membrane Fusion
R. Blumenthal, D. S. Dimitrov
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Annual Review of Cell and Developmental Biology, 2013
Shape changes and topological remodeling of membranes are essential for the identity of organelles and membrane trafficking. Although all cellular membranes have common features, membranes of different organelles create unique environments that support specialized biological functions.
James A, McNew +4 more
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Shape changes and topological remodeling of membranes are essential for the identity of organelles and membrane trafficking. Although all cellular membranes have common features, membranes of different organelles create unique environments that support specialized biological functions.
James A, McNew +4 more
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Protein-Mediated Membrane Fusion
Annual Review of Biophysics and Biophysical Chemistry, 1989PERSPECTIVES AND OVERVIEW 187 GEN ERAL CON CEPTS 188 Fusion Versus Fission 188 Endoplasmic and Exoplasmic Fusion Events 189 Tightness of Fusion 190 PHYSICAL FORCES BETWEEN MEMBRAN ES ........ 190 FUSION ASSAyS 191 LlPOSOMES AS TARGET MEMBRANES 192 EXOPLASMIC FUSION 193 Influenza Virus Fusion 193 Acid-Induced Conformational Change in ...
T, Stegmann, R W, Doms, A, Helenius
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