Results 51 to 60 of about 854,659 (323)

Membrane Fusion

open access: yesBioscience Reports, 2000
The fusion of biological membranes results in two bilayer-based membranes merging into a single membrane. In this process the lipids have to undergo considerable rearrangement. The nature of the intermediates that are formed during this rearrangement has been investigated. Certain fusion proteins facilitate this process. In many cases short segments of
openaire   +2 more sources

Physico-chemical requirements and kinetics of membrane fusion of flavivirus-like particles. [PDF]

open access: yes, 2015
Flaviviruses deliver their RNA genome into the host-cell cytoplasm by fusing their lipid envelope with a cellular membrane. Expression of the flavivirus pre-membrane and envelope glycoprotein genes in the absence of other viral genes results in the ...

core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Vesicle trafficking and vesicle fusion: mechanisms, biological functions, and their implications for potential disease therapy

open access: yesMolecular Biomedicine, 2022
Intracellular vesicle trafficking is the fundamental process to maintain the homeostasis of membrane-enclosed organelles in eukaryotic cells. These organelles transport cargo from the donor membrane to the target membrane through the cargo containing ...
Lele Cui   +9 more
doaj   +1 more source

Membrane Fusion☆

open access: yes, 2014
Entry of enveloped viruses is mediated by viral glycoproteins that catalyze fusion of viral and cellular membranes. These viral glycoproteins need to be activated which leads to extensive conformational changes that trigger the insertion or attachment of a fusion peptide in or to cellular target membranes thus bridging two bilayers.
Hock, M., Weissenhorn, W.
openaire   +1 more source

Crystallization of the oligopeptide-binding protein AppA from Bacillus subtilis [PDF]

open access: yes, 2004
AppA is the membrane-anchored extracellular receptor component of an ABC transporter responsible for the uptake of oligopeptides into Bacillus subtilis.
Blagova, E   +6 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Structural and functional analysis of vaccinia viral fusion complex component protein A28 through NMR and molecular dynamic simulations.

open access: yesPLoS Pathogens, 2023
Host cell entry of vaccinia virus (a poxvirus) proceeds through multiple steps that involve many viral proteins to mediate cell infection. Upon binding to cells, vaccinia virus membrane fuses with host membranes via a viral entry fusion protein complex ...
Chi-Fei Kao   +4 more
doaj   +1 more source

New mechanism of membrane fusion

open access: yes, 2001
We have carried out Monte Carlo simulation of the fusion of bilayers of single chain amphiphiles which show phase behavior similar to that of biological lipids. The fusion mechanism we observe is very different from the ``stalk'' hypothesis.
K. Katsov   +3 more
core   +1 more source

Fusion of isolated myoblast plasma membranes [PDF]

open access: yes, 1978
Fusion of plasma membranes isolated from myoblasts grown in culture has been investigated. 1. 1. Membrane fusion was specifically dependent on Ca2+ at physiological concentrations. However, at higher concentrations of cations, fusion could be triggered
Ahkong   +59 more
core   +1 more source

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