Results 71 to 80 of about 232,617 (270)
, 2019 Deciphering the complex interactions between neurotransmission and astrocytic $Ca^{2+}$ elevations is a target promising a comprehensive understanding of brain function.
Ivanov, Vladimir A. +2 more
core +1 more source
Structural diversity and biological significance of glycosphingolipids in pathogenic and opportunistic fungi [PDF]
, 2014 Glycosphingolipids (GSLs) are ubiquitous membrane components and have key roles in biological systems, acting as second messengers or modulators of signal transduction by affecting several events, ranging from cell adhesion, cell growth, cell motility ...
Anita Hilda Straus +5 more
core +2 more sources
Membrane biology: Do glycolipid microdomains really exist? [PDF]
Current Biology, 1998 Glycolipid membrane domains have been suggested to have a number of physiological functions, but do they actually exist in vivo or are they artefacts of extraction procedures? Recent data go some way towards showing that such glycolipid domains really are present within both model and cellular membranes.
openaire +2 more sources
Plasma membrane microdomains: Organization, function and trafficking (Review) [PDF]
Molecular Membrane Biology, 2004 The plasma membrane consists of a mosaic of functional microdomains facilitating a variety of physiological processes associated with the cell surface. In most cells, the majority of the cell surface is morphologically featureless, leading to difficulties in characterizing its organization and microdomain composition.
Laude AJ, Prior IA
openaire +3 more sources
Frontiers in PhysiologyIntroductionIntracellular Ca2+ signalling regulates membrane permeabilities, enzyme activity, and gene transcription amongst other functions. Large transmembrane Ca2+ electrochemical gradients and low diffusibility between cell compartments potentially ...
Marco D. Rodríguez +5 more
doaj +1 more source
Sphingolipids: membrane microdomains in brain development, function and neurological diseases [PDF]
Open Biology, 2017 Sphingolipids are highly enriched in the nervous system where they are pivotal constituents of the plasma membranes and are important for proper brain development and functions. Sphingolipids are not merely structural elements, but are also recognized as
Anne S. B. Olsen, Nils J. Færgeman
doaj +1 more source
Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction
Advanced Healthcare Materials, EarlyView.Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang +4 more
wiley +1 more source
Nature CommunicationsThe cell wall represents an essential structure conserved among most bacteria, playing a crucial role in growth and development. While extensively studied model bacteria have provided insights into cell wall synthesis coordination, the mechanism ...
Xiaobo Zhong +11 more
doaj +1 more source
European Journal of Cell BiologyNephrotic syndrome is frequently associated with pathogenic variants in NPHS2 (podocin), including the common and severe R138Q substitution. Using conditionally immortalized human podocytes expressing Myc-tagged podocin variants (G92C, V180M, R138Q ...
Pei-Chen Lu +6 more
doaj +1 more source
Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Advanced Healthcare Materials, EarlyView.Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source