Results 91 to 100 of about 29,208 (221)
Partitioning into ER membrane microdomains impacts autophagic protein turnover during cellular aging
Scientific ReportsEukaryotic membranes are compartmentalized into distinct micro- and nanodomains that rearrange dynamically in response to external and internal cues. This lateral heterogeneity of the lipid bilayer and associated clustering of distinct membrane proteins ...
Simon Prokisch, Sabrina Büttner
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Advanced Science, EarlyView.Cholesterol is revealed as a multitasking fuel for lung adenocarcinoma brain metastasis: it locks EGFR at the membrane to sustain AKT/NF‐κB–driven glycolysis and EMT, loosens the blood–brain barrier by promoting Claudin‐5 loss, and rewires microglia through IL‐4R lipid‐raft–JAK1/STAT6 signaling.
Ying Chen +14 more
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American Journal of Medical Genetics Part A, EarlyView.ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson +1 more
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Ceramide-enriched microdomains in planar membranes
Current Opinion in Colloid & Interface Science, 2010 Ceramide has a large effect on the properties of biological membranes, increasing lipid order and promoting lateral phase separation, and plays an important role in cell signaling. This review provides an overview of recent studies of the effects of direct ceramide incorporation and enzymatic ceramide generation on planar supported membranes, including
Zou, Shan, Johnston, Linda J.
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BMEMat, EarlyView.This Perspective explores the emerging landscape of cell membrane‐coated nanoparticles (CM‐NPs) as intelligent, immune‐compatible platforms for cancer therapy. Highlighting design strategies, translational challenges, and competitive positioning, it outlines how integrating biomimetic targeting with advanced analytical and manufacturing tools could ...
A. K. M. M. Alam +4 more
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Insulin Resistance as a Membrane Microdomain Disorder
ChemInform, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
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Mitochondria and the Actin Cytoskeleton in Neurodegeneration
Cytoskeleton, EarlyView.ABSTRACT Mitochondrial dysfunction and cytoskeletal disorganization are widely recognized hallmarks of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS).
Shivani Tuli +3 more
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BMC Cell Biology, 2004 Background Over the past decade, it has become apparent that specialised membrane microdomains, commonly called rafts, where lipids like sphingolipids and cholesterol are arranged compactly in a liquid ordered phase are involved in cell signalling ...
Joly Etienne
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ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.A hierarchical FeOOH–FeP@Ni3S2 electrocatalyst is engineered on 3D Ni foam to enable efficient alkaline oxygen evolution. Operando spectroscopic techniques reveal dynamic surface reconstruction and proton‐coupled electron transfer (PCET) kinetics. The catalyst exhibits low overpotential and industrial‐level current operation, driving high‐performance ...
Maria S. Metaxa +2 more
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Detergent-resistant plasma membrane proteomes for elucidating microdomain functions in plant cells
Frontiers in Plant Science, 2013 Although proteins and lipids have been assumed to be distributed homogeneously in the plasma membrane (PM), recent studies suggest that the PM is non-uniform, forming a structure that includes a number of lateral domains enriched in specific components ...
Daisuke eTakahashi +4 more
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