Results 181 to 190 of about 34,175 (279)

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

The FEBS Journal, EarlyView.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka, Matija Hrovatin, Bor Bokalj, Boris Turk   +3 more
wiley   +1 more source

Analysis of endocytosis at eisosomes

, 2011
The yeast plasma membrane contains at least three microdomains – membrane compartment containing Pma1 (MCP), membrane compartment containing TORC2 (MCT) and membrane compartment containing Can1 (MCC).
Rehman, Michael, Rehman, M.
core  

Biogenesis of TNF‐α‐insights into proteostasis and inflammation

The FEBS Journal, EarlyView.
TNF‐α biogenesis, trafficking, and signalling are tightly and reciprocally coupled to cellular proteostasis systems, including ER chaperones and endoplasmic reticulum‐associated degradation. This bidirectional crosstalk determines whether TNF‐α responses are adaptive or proteotoxic.
Bailasan Haidar, Céline Philippe, Eric Chevet, Jiří Zahradník   +3 more
wiley   +1 more source

The sorting nexin Snx21 promotes flotillin‐mediated endocytosis

The FEBS Journal, EarlyView.
In this study, we describe a novel function of the previously uncharacterized Snx21 protein as a specific positive regulator of flotillin‐mediated endocytic trafficking. Snx21 is recruited to endosomal membranes via binding to PI(3)P, and it colocalizes with flotillins on the surface of late endosomes.
Tamás Maruzs, Enikő Lakatos, Dalma Feil‐Börcsök, Gábor Juhász, Regina Mező, Asha Kiran Maddali, András Blastyák, Aladár Pettkó‐Szandtner, Hajnalka Laczkó‐Dobos, Gábor Juhász   +9 more
wiley   +1 more source

Multiple Kv1.5 targeting to membrane surface microdomains

Surface expression of voltage-dependent K+ channels (Kv) has a pivotal role in leukocyte physiology. Although little is known about the physiological role of lipid rafts, these microdomains concentrate signaling molecules and their ion channel substrates.
Martínez-Mármol, Ramón, Tamkun, Michael M., Soler Prat, Concepció, Solé, Laura, Vicente, Rubén, Felipe Campo, Antonio, Villalonga, Núria   +6 more
core   +3 more sources

FUNCTIONS OF MICRODOMAINS OF VACUOLAR MEMBRANE [PDF]

Book of proceedings of The Second All-Russian Scientific Conference with international participation "Regulation Mechanisms of Eukariotic Cell Organelle Functions", 2018
I.S. Nesterkina, N.V. Ozolina, E.V. Spiridonova, V.V. Gurina, V.N. Nurminsky, A.V. Tretiyakova   +5 more
openaire   +1 more source

OsCPN10a, cooperating with OsCPN20 and OsHSP60‐3B negatively regulate ABA signaling and enhance seed storability in rice

Journal of Integrative Plant Biology, EarlyView.
Abscisic acid signaling homeostasis is essential for seed storability. The molecular chaperone OsCPN10a enhances rice seed storability by forming a trimeric chaperone complex with OsCPN20‐OsHSP60‐3B that attenuates abscisic acid signaling via direct interaction with OsPYL10‐OsABIL1, thereby maintaining starch integrity and offering a promising target ...
Sufeng Liao, Yidong Wei, Yongsheng Zhu, Kunyang Li, Ting Chen, Shuai Zhao, Fangxi Wu, Jinlan Wang, Pengbo Yu, Hongguang Xie, Liping Chen, Qiuhua Cai, Huaan Xie, Jianfu Zhang   +13 more
wiley   +1 more source

Role of membrane microdomains in cardiac protection: strategies for diabetic cardiomyopathy. [PDF]

Am J Physiol Heart Circ Physiol
Zemljic-Harpf AE, Bonds JA, Zuniga-Hertz JP, Patel HH.   +3 more
europepmc   +1 more source

γ-Secretase Partitioning into Lipid Bilayers Remodels Membrane Microdomains after Direct Insertion. [PDF]

Langmuir, 2020
Barros M, Houlihan WJ, Paresi CJ, Brendel M, Rynearson KD, Lee CW, Prikhodko O, Cregger C, Chang G, Wagner SL, Gilchrist ML, Li YM.   +11 more
europepmc   +1 more source

CO2‐sensitive K+ channel traffic affects stomata and whole‐plant water use

Journal of Integrative Plant Biology, EarlyView.
CO2‐responsive regulation of membrane trafficking influences the density of the potassium ion (K+) channel KAT1 at the plasma membrane. CO2‐sensitive traffic, dependent on trafficking by the SNARE SYP121, impacts stomatal gas exchange and plant growth.
Zhiyi Yu, Sakharam Waghmare, Sahar Farami, Michael R. Blatt, Rucha Karnik   +4 more
wiley   +1 more source