Results 61 to 70 of about 7,291 (192)

Combined Effect of Nitrofurantoin and Plant Surfactant on Bacteria Phospholipid Membrane

Molecules, 2020
Due to the increasing use of antibiotics, measures are being taken to improve their removal from the natural environment. The support of biodegradation with natural surfactants that increase the bioavailability of impurities for microorganisms that ...
Monika Rojewska, Wojciech Smułek, Krystyna Prochaska, Ewa Kaczorek   +3 more
doaj   +1 more source

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

Ultra-Low Pressure Filtration Performance in Campus Domestic Waste [PDF]

E3S Web of Conferences
This study aims to determine the effect of ultra-low pressure filtration performance on the permeability of clean water and campus domestic waste. Waste treatment can be carried out by applying an ultra-low pressure membrane filtration process with a ...
Khery Yusran, Cordella Rhamdhani Devinna, Roil Bilad Muhamad, Asma Nufida Baiq, Ahzan Sukainil   +4 more
doaj   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Permeability across lipid membranes

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2016
Molecular permeation through lipid membranes is a fundamental biological process that is important for small neutral molecules and drug molecules. Precise characterization of free energy surface and diffusion coefficients along the permeation pathway is required in order to predict molecular permeability and elucidate the molecular mechanisms of ...
openaire   +2 more sources

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

Advanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon, Hee Su Sohn, Jong Sang Yoon, So Won Jeon, Hee Gyeong Ko, Min‐Ho Kang, Jisun Lee, Jae‐Hwan Nam, Louis T. Merriam, Edy Y. Kim, Han Young Kim   +10 more
wiley   +1 more source

A new PAMPA model proposed on the basis of a synthetic phospholipid membrane.

PLoS ONE, 2015
The purpose of this work was to investigate the synthetic phospholipid dependence of permeability measured by parallel artificial membrane permeability assay (PAMPA) method.
Hui Yu, Qi Wang, Ying Sun, Ming Shen, He Li, Yourong Duan   +5 more
doaj   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

Cyclic peptide membrane permeability prediction using deep learning model based on molecular attention transformer

Frontiers in Bioinformatics
Membrane permeability is a critical bottleneck in the development of cyclic peptide drugs. Experimental membrane permeability testing is costly, and precise in silico prediction tools are scarce.
Dawei Jiang, Zixi Chen, Zixi Chen, Hongli Du   +3 more
doaj   +1 more source

Coordinated Multi‐Component Gradient Engineering of Catalyst Layers for Advanced Polymer Electrolyte Fuel Cells

Advanced Functional Materials, EarlyView.
This work presents a continuous linear gradient catalyst layer design, a general strategy for improving membrane electrode assemblies across electrochemical devices. Fabricated via a dual‐nozzle spray coating method, the architecture controls the Pt/carbon ratio, ionomer content and ionomer type across the catalyst layer, enhancing proton conduction ...
Shangwei Zhou, Matt P. Tudball, Yiming Guo, Bia Brandt, Adam Zucconi, Wenjia Du, Junfu Bu, Daniel H. C. Wan, Jianuo Chen, Emanuele Magliocca, Feng Ryan Wang, Alexander J.E. Rettie, Patrick S. Grant, Paul R. Shearing, Rhodri Jervis, Thomas S. Miller   +15 more
wiley   +1 more source