Results 61 to 70 of about 642,713 (354)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Optimization of experimental conditions for skin-PAMPA measurements

ADMET and DMPK, 2020
In recent years, the parallel artificial membrane permeability assay (PAMPA) has been extended for prediction of skin permeation by developing an artificial membrane which mimics the stratum corneum structure, skin-PAMPA.
Sara Soriano-Meseguer, Elisabet Fuguet, Adriana Port, Martí Rosés   +3 more
doaj   +1 more source

Lysosome membrane permeability to anions

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1998
The permeability of rat liver lysosomes to some inorganic and aliphatic organic anions was investigated, using an osmotic-protection methodology. Lysosomes were incubated at 25 degreesC in 250 mOsm solutions of potassium salts of the anions, in the presence of valinomycin, and the latency of lysosomal hexosaminidase measured at intervals.
Ann R. Klemm, Lisa M. Anderson, Katherine L. Pell, John B. Lloyd, Carole L. Andrew   +4 more
openaire   +3 more sources

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

CO2 Permeability of Biological Membranes and Role of CO2 Channels

Membranes, 2017
We summarize here, mainly for mammalian systems, the present knowledge of (a) the membrane CO2 permeabilities in various tissues; (b) the physiological significance of the value of the CO2 permeability; (c) the mechanisms by which membrane CO2 ...
Volker Endeward, Mariela Arias-Hidalgo, Samer Al-Samir, Gerolf Gros   +3 more
doaj   +1 more source

Bilayer Heterogeneous Cation Exchange Membrane with Polyaniline Modified Homogeneous Layer: Preparation and Electrotransport Properties

Membranes, 2023
A bilayer membrane based on a heterogenous cation exchange membrane with a homogeneous cation exchange layer and a polyaniline on its surface is prepared.
Natalia Loza, Irina Falina, Natalia Kutenko, Svetlana Shkirskaya, Julia Loza, Natalia Kononenko   +5 more
doaj   +1 more source

Importance of Lipid Composition in the Membrane Dynamics of Urothelial Umbrella Cells [PDF]

, 2014
The studies on membrane dynamics in urinary bladder umbrella cells were focused on proteins as important factors for maintaining the permeability barrier and their role as pathways modulators for the discoidal/fusiform endocytic vesicles which is one of ...
Grasso, Ernesto Javier
core  

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

Combined Effect of Nitrofurantoin and Plant Surfactant on Bacteria Phospholipid Membrane

Molecules, 2020
Due to the increasing use of antibiotics, measures are being taken to improve their removal from the natural environment. The support of biodegradation with natural surfactants that increase the bioavailability of impurities for microorganisms that ...
Monika Rojewska, Wojciech Smułek, Krystyna Prochaska, Ewa Kaczorek   +3 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source