Results 101 to 110 of about 14,870,238 (380)
Styrylpyridinium Derivatives as New Potent Antifungal Drugs and Fluorescence Probes
Frontiers in Microbiology, 2020 The incidence of Candida glabrata infections increases every year due to its higher resistance to commonly used antifungal drugs. We characterized the antifungal mechanism of action of eight new styrylpyridinium derivatives, with various N-alkyl chains (-
Simona Vaitkienė +3 more
doaj +1 more source
Fluctuation spectra of free and supported membrane pairs
, 2006 Fluctuation spectra of fluid compound membrane systems are calculated. The systems addressed contain two (or more) almost parallel membranes that are connected by harmonic tethers or by a continuous, harmonic confining potential.
Merath, Rolf-Juergen, Seifert, Udo
core +1 more source
Characteristics of temporal fluctuations in the hyperpolarized state of the cortical slow oscillation [PDF]
, 2008 We present evidence for the hypothesis that transitions between the low- and high-firing states of the cortical slow oscillation correspond to neuronal phase transitions. By analyzing intracellular recordings of the membrane potential during the cortical
Barry, Melissa +4 more
core +2 more sources
Open Biology, 2012 Summary Missense mutations in PTEN-induced kinase 1 (PINK1) cause autosomal-recessive inherited Parkinson's disease (PD). We have exploited our recent discovery that recombinant insect PINK1 is catalytically active to test whether PINK1 directly ...
Chandana Kondapalli +12 more
semanticscholar +1 more source
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
Spike-Threshold Adaptation Predicted by Membrane Potential Dynamics In Vivo
PLoS Comput. Biol., 2014 Neurons encode information in sequences of spikes, which are triggered when their membrane potential crosses a threshold. In vivo, the spiking threshold displays large variability suggesting that threshold dynamics have a profound influence on how the ...
Bertrand Fontaine, J. Peña, R. Brette
semanticscholar +1 more source
Donnan Membrane Potential [PDF]
Nature, 1944 IN a recent communication in NATURE (July 17, 1943, p. 76) I applied the Boltzmann distribution law to the Donnan membrane equilibrium between two compartments, compartment (1) containing colloidal (or non-diffusible) ions plus diffusible ions, compartment (2) containing only diffusible ions. From the equations obtained, it follows that at the same pH.
openaire +2 more sources
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
FEBS Letters, EarlyView.In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
Инженерные технологии и системы, 2020 Introduction. Spring wheat yield depends largely on the wheat variety, seed quality, cultivation technology, and agro-climatic factors. It has been found that the separation of wheat seeds into fractions makes it possible to improve the quality of post ...
Nadezhda N. Barysheva +3 more
doaj +1 more source
Membrane repair against H. pylori promotes cancer cell proliferation [PDF]
, 2010 Membrane repair is a universal response against physical and biological insults and enables cell survival. Helicobacter pylori is one of the most common human pathogens and the first formally recognized bacterial carcinogen associated with gastric cancer.
Chiung-Nien Chen +5 more
core +1 more source