Results 121 to 130 of about 11,716,491 (307)

Sensing membrane curvature [PDF]

open access: yes, 2003
Transport vesicle formation and fusion are highly regulated processes that require the sequential assembly and disassembly of proteinacious membrane coats.
Burger, Koert N.J   +8 more
core   +2 more sources

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Furan fatty acids efficiently rescue brain cells from cell death induced by oxidative stress [PDF]

open access: yes, 2013
Treatment of rat brain C6 astroglioma cells with furan fatty acid F6 prior to exposure to hydrogen peroxide shows a strong protective effect of F6 against cell death resulting from oxidative stress.
Cox, R.C.   +6 more
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Deficiency of dltD contributes to increased autolysis in Streptococcus mutans

open access: yesJournal of Oral Microbiology
Streptococcus mutans (S. mutans) is one of the major etiological agents of dental caries. Interfering with the expression of genes associated with cariogenicity of S. mutans is an effective ecological approach for caries prevention.
Jingyun Du   +6 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Assessment of oil fouling by oil-membrane interaction energy analysis

open access: yes, 2018
Membrane-filtration is promising for treating the voluminous oily wastewater, especially when the oil emulsions are smaller than 20 µm. However, studies on the inevitable membrane fouling phenomenon by oil are rather scarce.
Tanudjaja, Henry Jonathan   +3 more
core   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Effect of external periodic signals and electromagnetic radiation on autaptic regulation of neuronal firing

open access: yesIET Systems Biology, 2018
An improved Hindmarsh–Rose (HR) neuron model, where the memristor is a bridge between membrane potential and magnetic flux, can be used to investigate the effect of periodic signals on autaptic regulation of neurons under electromagnetic radiation. Based
Mengyan Ge   +8 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

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