Results 111 to 120 of about 14,870,238 (380)

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

open access: yesJournal of Cell Biology, 2010
Differential localization to the inner and outer mitochondrial membranes regulates PINK1 stability and function.
S. Jin   +5 more
semanticscholar   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Heterogeneous Expression of T-type Ca2+ Channels Defines Different Neuronal Populations in the Inferior Olive of the Mouse

open access: yesFrontiers in Cellular Neuroscience, 2016
The neurons in the inferior olive express subthreshold oscillations in their membrane potential. This oscillatory activity is known to drive synchronous activity in the cerebellar cortex and plays a role in motor learning and motor timing.
Paolo Bazzigaluppi, Marcel T G De Jeu
doaj   +1 more source

Effective zero-thickness model for a conductive membrane driven by an electric field

open access: yes, 2009
The behavior of a conductive membrane in a static (DC) electric field is investigated theoretically. An effective zero-thickness model is constructed based on a Robin-type boundary condition for the electric potential at the membrane, originally ...
B. Hille   +9 more
core   +1 more source

Neural superposition and oscillations in the eye of the blowfly [PDF]

open access: yes, 1987
Neural superposition in the eye of the blowfly Calliphora erythrocephala was investigated by stimulating single photoreceptors using corneal neutralization through water immersion.
D Burkhardt   +18 more
core   +2 more sources

Structural and functional properties of SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19

open access: yesActa Pharmacologica Sinica, 2020
Coronavirus disease 2019 is a newly emerging infectious disease currently spreading across the world. It is caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Yuan Huang   +4 more
semanticscholar   +1 more source

Fluorinated Membrane Potential Probes [PDF]

open access: yesBiophysical Journal, 2011
To explore the effect of fluorination on photophysical properties of membrane potential probes, we developed synthetic methods for ANEP dyes with fluorine substitutions at the donor, bridge, and acceptor sides. Fluorination on acceptor side induces red shifts in optical spectra while on donor side it induces blue shifts.
Adrian Negrean   +3 more
openaire   +2 more sources

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

open access: yesFEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi   +5 more
wiley   +1 more source

Attractive asymmetric inclusions in elastic membranes under tension: cluster phases and membrane invaginations

open access: yes, 2013
Up-down asymmetric inclusions impose a local, spontaneous curvature to an elastic membrane. When several of them are inserted in a same membrane, they feel effective forces mediated by the membrane, both of elastic and entropic nature.
Destainville, Nicolas, Weitz, Sebastian
core   +3 more sources

Mitochondrial membrane potential probes and the proton gradient: a practical usage guide.

open access: yesBioTechniques, 2011
Fluorescent probes for monitoring mitochondrial membrane potential are frequently used for assessing mitochondrial function, particularly in the context of cell fate determination in biological and biomedical research.
S. Perry   +4 more
semanticscholar   +1 more source

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