Results 121 to 130 of about 14,870,238 (380)
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile+8 more
wiley +1 more source
Six principles of visual cortical dynamics
A fundamental goal in vision science is to determine how many neurons in how many areas are required to compute a coherent interpretation of the visual scene.
Per E Roland
doaj +1 more source
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source
Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke+2 more
wiley +1 more source
Potential impacts for monitoring sustainability: case study of hollow fiber membrane [PDF]
Sustainability level is a new indicator of quality and efficiency for product life cycle. Sustainability should be balanced among Triple Bottom Line (TBL) aspects namely environmental, economic and social elements.
Hemdi, Abdul Rahman+3 more
core
Membrane potential dynamics of grid cells
During navigation, grid cells increase their spike rates in firing fields arranged on a markedly regular triangular lattice, whereas their spike timing is often modulated by theta oscillations.
Cristina Domnisoru+2 more
semanticscholar +1 more source
STUDIES ON THE MEMBRANE POTENTIAL
The charge of the small particles of mercury containing various kind of metals in the electrolytic solution was investigated, Employed method was that the deflection of small particles falling from a fine hole of glass tube into the solution through which current was flowing in horizontal direction was observed.
Tohru Murakami, Katsuzo Chosa
openaire +3 more sources
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican+7 more
wiley +1 more source
Tolvaptan (TLV), an oral non-peptide antagonist of vasopressin V2 receptor, has been increasingly used for managements in patients with hyponatremia and/or syndrome of inappropriate antidiuretic hormone secretion.
Te-Ling Lu+4 more
doaj +1 more source
Macroscopic tunneling of a membrane in an optomechanical double-well potential
The macroscopic tunneling of an optomechanical membrane is considered. A cavity mode which couples quadratically to the membranes position can create highly tunable adiabatic double-well potentials, which together with the high Q-factors of such ...
Buchmann, L. F.+3 more
core +1 more source