Results 71 to 80 of about 14,693,728 (394)
The interaction of metal oxide nanoparticles (NPs) with cells and lipid bilayers is precarious in various fields such as antibacterial and drug or gene delivery.
Maya S Khater+4 more
doaj +1 more source
Age-Related Unstructured Spike Patterns and Molecular Localization in Drosophila Circadian Neurons
Aging decreases sleep quality by disrupting the molecular machinery that regulates the circadian rhythm. However, we do not fully understand the mechanism that underlies this process.
Dieu Linh Nguyen+5 more
doaj +1 more source
Natural channel protein inserts and functions in a completely artificial, solid-supported bilayer membrane [PDF]
Reconstitution of membrane proteins in artificial membrane systems creates a platform for exploring their potential for pharmacological or biotechnological applications.
Fu, Wangyang+3 more
core +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Effects of lithium on electrical activity and potassium ion distribution in the vertebrate central nervous system [PDF]
Three different regions of the vertebrate central nervous system maintained in vitro (frog spinal cord, guinea pig olfactory cortex and hippocampus) have been used to investigate how Li+ influences membrane potential, membrane resistance, action ...
Aldenhoff+45 more
core +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Six principles of visual cortical dynamics
A fundamental goal in vision science is to determine how many neurons in how many areas are required to compute a coherent interpretation of the visual scene.
Per E Roland
doaj +1 more source
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
Dependence of serosal membrane potential on mucosal membrane potential in toad urinary bladder
Ussing's model for sodium transport across epithelia assumes the existence of two barriers in series; the outer barrier behaves as a sodium electrode and the inner barrier as a potassium electrode (Koefoed-Johnsen and Ussing, 1958); furthermore, these membranes are supposed to be independent of one another.
A.L. Finn, L. Reuss
openaire +3 more sources
In this protocol, we introduced a method of measuring mitochondrial dysfunction to confirm the epithelial–mesenchymal transition (EMT) in pancreatic cancer cells under a hypoxic environment. There are many expertized and complicated methods to verify EMT.
Jae Jun Sim, Keun-Yeong Jeong
doaj +1 more source