Pigment epithelium-derived factor protects retinal ganglion cells from hypoxia-induced apoptosis by preventing mitochondrial dysfunction [PDF]
International Journal of Ophthalmology, 2017 AIM: To investigate the potential of pigment epithelium-derived factor (PEDF) to protect the immortalized rat retinal ganglion cells-5 (RGC-5) exposed to CoCl2-induced chemical hypoxia.
Shu-Wei Tian +4 more
doaj +1 more source
Modelling of the Electrical Membrane Potential for Concentration Polarization Conditions
Entropy, 2022 Based on Kedem–Katchalsky formalism, the model equation of the membrane potential (Δψs) generated in a membrane system was derived for the conditions of concentration polarization.
Kornelia M. Batko +4 more
doaj +1 more source
A Promising Method for the Determination of Cell Viability: The Membrane Potential Cell Viability Assay [PDF]
, 2022 Eneko Madorran +4 more
openalex +1 more source
Role of physiological ClC-1 Cl- ion channel regulation for the excitability and function of working skeletal muscle. [PDF]
, 2016 Electrical membrane properties of skeletal muscle fibers have been thoroughly studied over the last five to six decades. This has shown that muscle fibers from a wide range of species, including fish, amphibians, reptiles, birds, and mammals, are all ...
Chen, Tsung-Yu +4 more
core +1 more source
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Membrane repair against H. pylori promotes cancer cell proliferation [PDF]
, 2010 Membrane repair is a universal response against physical and biological insults and enables cell survival. Helicobacter pylori is one of the most common human pathogens and the first formally recognized bacterial carcinogen associated with gastric cancer.
Chiung-Nien Chen +5 more
core +1 more source
Effective zero-thickness model for a conductive membrane driven by an electric field
, 2009 The behavior of a conductive membrane in a static (DC) electric field is investigated theoretically. An effective zero-thickness model is constructed based on a Robin-type boundary condition for the electric potential at the membrane, originally ...
B. Hille +9 more
core +1 more source
Characteristics of temporal fluctuations in the hyperpolarized state of the cortical slow oscillation [PDF]
, 2008 We present evidence for the hypothesis that transitions between the low- and high-firing states of the cortical slow oscillation correspond to neuronal phase transitions. By analyzing intracellular recordings of the membrane potential during the cortical
Barry, Melissa +4 more
core +2 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Sesquiterpene from Polygonum Barbatum Disrupt Mitochondrial Membrane Potential to Induce Apoptosis and Inhibits Metastasis by Downregulating Matrix Metalloproteinase and Osteopontin in NCI-H460 Cells [PDF]
, 2021 Binte Zehra +8 more
openalex +1 more source