Results 71 to 80 of about 3,357,590 (333)

The role of DJ-1 in enhancing mitochondrial quality control [PDF]

, 2013
Thesis (M.A.)--Boston UniversityDJ-1 is a cytosolic sensor for oxidative damage which acts on the Mitochondria. It works to curb the negative effects of high membrane potential in mitochondria, but the mechanism of action is still uncertain.
Lingiah, Krishna Anand
core   +1 more source

Behaviours of natural organic matter in membrane filtration for surface water treatment : a review [PDF]

, 2006
Membrane application in surface water treatment provides many advantages over conventional treatment. However, this effort is hampered by the fouling issue, which restricts its widespread application due to increases in hydraulic resistances, operational
Ismail, A. F., Salim, Razman, Zularisam, A. W.   +2 more
core   +1 more source

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

FEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke, Nils Alexander Lakomek, Georg Groth   +2 more
wiley   +1 more source

MODULATION OF DEFENSIVE REFLEX CONDITIONING IN SNAILS BY SEROTONIN

Frontiers in Behavioral Neuroscience, 2015
We studied the role of serotonin in the mechanisms of learning in terrestrial snails. To produce a serotonin deficit, the neurotoxic analogues of serotonin, 5,6- or 5,7-dihydroxytryptamine (5,6/5,7-DHT) were used.
Vyatcheslav V Andrianov, Vyatcheslav V Andrianov, Tatiana Kh Bogodvid, Tatiana Kh Bogodvid, Irina B Deryabina, Aleksandra N Golovchenko, Lyudmila N Muranova, Roza R Tagirova, Alia Kh Vinarskaya, Khalil L Gainutdinov, Khalil L Gainutdinov   +10 more
doaj   +1 more source

Electrostatics of ions inside the nanopores and trans-membrane channels

, 2006
A model of a finite cylindrical ion channel through a phospholipid membrane of width $L$ separating two electrolyte reservoirs is studied. Analytical solution of the Poisson equation is obtained for an arbitrary distribution of ions inside the trans ...
Corry B., Doyle D. A., Hille B., Jackson J. D., Jordan P. C., Jordan P. C., Kuyucak S., Levin Y., Levitt D. G., Moy G., Smythe W. R., Teber S., Tieleman D. P., Y Levin   +13 more
core   +1 more source

Human hepatic cell behavior on polysulfone membrane with double porosity level [PDF]

, 2013
In the membrane-based bioartificial livers developed up to now,the hepatic cells were located either in the fibers lumen or in the cartridge,with limited capacity for cell hosting.Here,we designed a polysulfone (PSU) membrane with a double porosity ...
Adrianus, Gerard Nathanael, Aimar, Pierre, Bacchin, Patrice, Cerino, Giulia, Dufresne, Murielle, Legallais, Cécile, Remigy, Jean-Christophe   +6 more
core   +2 more sources

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

De Novo Emergence of Peptides That Confer Antibiotic Resistance

mBio, 2019
The origin of novel genes and beneficial functions is of fundamental interest in evolutionary biology. New genes can originate from different mechanisms, including horizontal gene transfer, duplication-divergence, and de novo from noncoding DNA sequences.
Michael Knopp, Jonina S. Gudmundsdottir, Tobias Nilsson, Finja König, Omar Warsi, Fredrika Rajer, Pia Ädelroth, Dan I. Andersson   +7 more
doaj   +1 more source

Imaging mitochondrial membrane potentials

Biophysical Journal, 1993
process remain to be elucidated. The elusiveness of this goal can be attributed, at least in part, to the absence of structural information about the mitochondrion itself at several levels of complexity. It is obvious, for example, that obtaining atomic structures of the respiratory chain protein complexes by x-ray or electron crystallography would ...
openaire   +3 more sources

How Well Can You Tailor the Charge of Lipid Vesicles? [PDF]

, 2019
Knowledge and control of surface charge or potential is important for tailoring colloidal interactions. In this work, we compare widely used zeta potential (ζ) measurements of charged lipid vesicle surface potential to direct measurements using the ...
Docto, D, Gilbile, D, Kingi, DT, Kuhl, TL, Kurniawan, J, Monahan, D, Tang, A   +6 more
core   +2 more sources