Results 71 to 80 of about 3,424,825 (277)

Requirement of a Membrane Potential for the Posttranslational Transfer of Proteins into Mitochondsria [PDF]

, 1982
Posttranslational transfer of most precursor proteins into mitochondria is dependent on energization of the mitochondria. Experiments were carried out to determine whether the membrane potential or the intramitochondrial ATP is the immediate energy ...
Conboy J. G., Cote C., Daniels C. J., Data T., Date T., Enequist H. G., Graven S. N., Hallermayer G., Harmey M. A., Harmey M. A., Heldt H. W., Heytler P. G., Josefson L. G., Kekssler S. W., Korb H., Kovac L., Laemmli U. K., Lambowitz A. M., Lambowitz A. M., Maccechini M.-L., Matsuura S., Michel R., Mori M., Mori M., Nelson N., Passarella S., Pelham H. R. B., Raymond Y., Sebald W., Sebald W., Stigall D. L., Subik J., Tzagoloff A., Vignais P. V., Weiss H., Zimmermann R., Zimmermann R., Zimmermann R.   +37 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Electrostatics of ions inside the nanopores and trans-membrane channels

, 2006
A model of a finite cylindrical ion channel through a phospholipid membrane of width $L$ separating two electrolyte reservoirs is studied. Analytical solution of the Poisson equation is obtained for an arbitrary distribution of ions inside the trans ...
Corry B., Doyle D. A., Hille B., Jackson J. D., Jordan P. C., Jordan P. C., Kuyucak S., Levin Y., Levitt D. G., Moy G., Smythe W. R., Teber S., Tieleman D. P., Y Levin   +13 more
core   +1 more source

Is resistance to ischaemia of motor axons in diabetic subjects due to membrane depolarization? [PDF]

, 1990
The reasons for the resistance to ischaemia of peripheral nerves in diabetics are not well understood. We have now explored whether axonal depolarization underlies this phenomenon, as has previously been proposed.
Baker, Barrett, Bergmans, Bergmans, Bostock, Das, Dyck, Gilliat, Greene, Gregersen, Horowitz, Hugh Bostock, Jaramillo, Klaus Piwernetz, Low, Low, Ludin, Masson, Michael Strupp, Newrick, Oh, Parry, Paul Weigl, Peter Grafe, Ritchie, Rolf Renner, Shirabe, Steiness, Steiness, Steiness, Strupp, Stöhr, Thomas, Tuck, Weigl   +34 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Membrane Potential

, 2014
Citation: 'membrane potential' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.M03825 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
A.A. Ramahi, R.L. Ruff
openaire   +2 more sources

Potential impacts for monitoring sustainability: case study of hollow fiber membrane [PDF]

, 2017
Sustainability level is a new indicator of quality and efficiency for product life cycle. Sustainability should be balanced among Triple Bottom Line (TBL) aspects namely environmental, economic and social elements.
Hemdi, Abdul Rahman, Mahmood, Salwa, Mat Saman, Muhamad Zameri, Zakuan, Norhayati   +3 more
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Microbe-Derived Indole Metabolite Demonstrates Potent Multidrug Efflux Pump Inhibition in Staphylococcus aureus

Frontiers in Microbiology, 2019
Efflux pumps are always at the forefront of bacterial multidrug resistance and account for the failure of antibiotics. The present study explored the potential of 2-(2-Aminophenyl) indole (RP2), an efflux pump inhibitor (EPI) isolated from the soil ...
Rushikesh Tambat, Manoj Jangra, Nisha Mahey, Nishtha Chandal, Manpreet Kaur, Surbhi Chaudhary, Dipesh Kumar Verma, Krishan Gopal Thakur, Manoj Raje, Sanjay Jachak, Neeraj Khatri, Hemraj Nandanwar   +11 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source