Results 111 to 120 of about 672,438 (373)

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Behavior of hydrophobic ionic liquids as liquid membranes on phenol removal: Experimental study and optimization [PDF]

open access: yesDesalination, Vol. 278, No. 1-3, pp. 250-258, 2011, 2014
Room temperature ionic liquids show potential as an alternative to conventional organic membrane solvents mainly due to their properties of low vapor pressure, low volatility and they are often stable. In the present work, the technical feasibilities of room temperature ionic liquids as bulk liquid membranes for phenol removal were investigated ...
arxiv  

Menthol Modulates Pacemaker Potentials through TRPA1 Channels in Cultured Interstitial Cells of Cajal from Murine Small Intestine

open access: yesCellular Physiology and Biochemistry, 2016
Background/Aims: ICCs are the pacemaker cells responsible for slow waves in gastrointestinal (GI) smooth muscle, and generate periodic pacemaker potentials in current-clamp mode.
Hyun Jung Kim   +5 more
doaj   +1 more source

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

Plateau Potential Fluctuations and Intrinsic Membrane Noise [PDF]

open access: yes, 2017
This thesis focuses on subthreshold membrane potential fluctuations in the plateau potentials of bistable neurons. Research involved with plateau potentials typically finds one of the resting membrane potentials to be more susceptible to voltage ...
Borrus, Daniel Scott
core   +1 more source

Modeling Depolarization Delay, Sodium Currents, and Electrical Potentials in Cardiac Transverse Tubules

open access: yesFrontiers in Physiology, 2019
T-tubules are invaginations of the lateral membrane of striated muscle cells that provide a large surface for ion channels and signaling proteins, thereby supporting excitation–contraction coupling. T-tubules are often remodeled in heart failure.
Sarah Helena Vermij   +2 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Single-channel recordings from cultured human retinal pigment epithelial cells. [PDF]

open access: yes, 1988
We have applied patch-clamp techniques to on-cell and excised-membrane patches from human retinal pigment epithelial cells in tissue culture. Single-channel currents from at least four ion channel types were observed: three or more potassium-selective ...
Fain, GL, Fox, JA, Pfeffer, BA
core  

Relationship Between Some Parameters of the Membrane-Redox Potentials Three-State Line System with the Human Constitutional Types of Traditional Medicine

open access: yesCentral Asian Journal of Medical Sciences, 2015
Objectives: According to Tibetan-Mongolian traditional medicine theory, humans are classified into three main individuals based on the Rlung, Mkhris or Badgan symbolic code (SC).
Narantsetseg Badarch   +3 more
doaj   +1 more source

Knocking down TRPM2 expression reduces cell injury and NLRP3 inflammasome activation in PC12 cells subjected to oxygen-glucose deprivation

open access: yesNeural Regeneration Research, 2020
Transient receptor potential melastatin 2 (TRPM2) is an important ion channel that represents a potential target for treating injury caused by cerebral ischemia.
Tao Pan   +7 more
doaj   +1 more source

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