Results 111 to 120 of about 438,564 (323)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Theta oscillations represent collective dynamics of multineuronal membrane potentials of murine hippocampal pyramidal cells. [PDF]

Commun Biol, 2023
Noguchi A, Yamashiro K, Matsumoto N, Ikegaya Y.   +3 more
europepmc   +1 more source

Adhesion-induced lateral phase separation of multi-component membranes: the effect of repellers and confinement

, 2008
We present a theoretical study for adhesion-induced lateral phase separation for a membrane with short stickers, long stickers and repellers confined between two hard walls.
B. Alberts, Hsuan-Yi Chen, K. Binder, K. Huang, Mesfin Asfaw, R. Lipowsky   +5 more
core   +1 more source

Mathematical expression of membrane potential based on Ling’s adsorption theory is approximately the same as the Goldman–Hodgkin–Katz equation [PDF]

, 2018
Hirohisa Tamagawa
openalex   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

ELFENN: A Generalized Platform for Modeling Ephaptic Coupling in Spiking Neuron Models

Frontiers in Neuroinformatics, 2019
The transmembrane ionic currents that underlie changes in a cell's membrane potential give rise to electric fields in the extracellular space. In the context of brain activity, these electric fields form the basis for extracellularly recorded signals ...
Aaron R. Shifman, Aaron R. Shifman, Aaron R. Shifman, John E. Lewis, John E. Lewis, John E. Lewis   +5 more
doaj   +1 more source

Spiking Neural P Systems with Membrane Potentials, Inhibitory Rules, and Anti-Spikes. [PDF]

Entropy (Basel), 2022
Liu Y, Zhao Y.
europepmc   +1 more source

Universal amplitudes of the Casimir-like interactions between four types of rods in fluid membranes

, 2011
The fluctuation-induced, Casimir-like interaction between two parallel rods of length L adsorbed on a fluid membrane is calculated analytically at short separations ...
Bitbol, Anne-Florence, Fournier, Jean-Baptiste, Ronia, Kévin Sin   +2 more
core   +3 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Multitask learning of a biophysically-detailed neuron model.

PLoS Computational Biology
The human brain operates at multiple levels, from molecules to circuits, and understanding these complex processes requires integrated research efforts.
Jonas Verhellen, Kosio Beshkov, Sebastian Amundsen, Torbjørn V Ness, Gaute T Einevoll   +4 more
doaj   +1 more source