Results 41 to 50 of about 10,936,171 (356)

Circular dichroism spectroscopy of membrane proteins.

Chemical Society Reviews, 2016
Circular dichroism (CD) spectroscopy is a well-established technique for studying the secondary structures, dynamics, folding pathways, and interactions of soluble proteins, and is complementary to the high resolution but generally static structures ...
Andrew J. Miles, Bonnie A. Wallace
semanticscholar   +1 more source

Structure of Human ATG9A, the Only Transmembrane Protein of the Core Autophagy Machinery

Cell Reports, 2020
Summary: Autophagy is a catabolic process involving capture of cytoplasmic materials into double-membraned autophagosomes that subsequently fuse with lysosomes for degradation of the materials by lysosomal hydrolases.
Carlos M. Guardia, Xiao-Feng Tan, Tengfei Lian, Mitra S. Rana, Wenchang Zhou, Eric T. Christenson, Augustus J. Lowry, José D. Faraldo-Gómez, Juan S. Bonifacino, Jiansen Jiang, Anirban Banerjee   +10 more
doaj   +1 more source

Membrane protein secretases [PDF]

Biochemical Journal, 1997
A diverse range of membrane proteins of Type I or Type II topology also occur as a circulating, soluble form. These soluble forms are often derived from the membrane form by proteolysis by a group of enzymes referred to collectively as ‘secretases‘ or ‘sheddases’.
N M, Hooper, E H, Karran, A J, Turner
openaire   +2 more sources

Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

Nature Communications, 2020
Glucagon-like peptide-1 receptor is an important regulator of appetite and glucose homeostasis. Here the authors describe super-resolution microscopy and in vivo imaging compatible fluorescent probes, which reveal endogenous glucagon-like peptide-1 ...
Julia Ast, Anastasia Arvaniti, Nicholas H. F. Fine, Daniela Nasteska, Fiona B. Ashford, Zania Stamataki, Zsombor Koszegi, Andrea Bacon, Ben J. Jones, Maria A. Lucey, Shugo Sasaki, Daniel I. Brierley, Benoit Hastoy, Alejandra Tomas, Giuseppe D’Agostino, Frank Reimann, Francis C. Lynn, Christopher A. Reissaus, Amelia K. Linnemann, Elisa D’Este, Davide Calebiro, Stefan Trapp, Kai Johnsson, Tom Podewin, Johannes Broichhagen, David J. Hodson   +25 more
doaj   +1 more source

Influences of Excluded Volume of Molecules on Signaling Processes on Biomembrane [PDF]

, 2013
We investigate the influences of the excluded volume of molecules on biochemical reaction processes on 2-dimensional surfaces using a model of signal transduction processes on biomembranes.
A Ashkenazi, A Kinjo, A Kusumi, AA Butler, AB Fulton, AC Dreux, AG Gilman, Akinori Awazu, AP Minton, AP Minton, AP Minton, AP Minton, C Fernández, C Fritsch, C Nakada, D Bray, D Hall, D Kilburn, DA White, E Nishida, F Daumas, F Ozcan, GI Mashanov, H Shankaran, Hiraku Nishimori, J Kim, J Lin, JL Macdonald, Johannes Reisert, K Aoki, K Mayawala, K Suzuki, K Takahashi, L Chang, M Agrawal, M Cheung, M Jiao, M Qi, M Saitoh, Masashi Fujii, MD Shtilerman, MJ Saxton, PM Janssens, RJ Ellis, RJ Orton, RWC Wong, S Matsuoka, S Matsuoka, S Nagarajan, SB Zimmerman, SP van derWoning, SY Bhide, T Fujiwara, WX Schulze, Y Lill, Y Miyanaga, Z Chen   +56 more
core   +3 more sources

Modular detergents tailor the purification and structural analysis of membrane proteins including G-protein coupled receptors [PDF]

, 2020
Detergents enable the purification of membrane proteins and are indispensable reagents instructural biology. Even though a large variety of detergents have been developed in the lastcentury, the challenge remains to identify guidelines that allowfine ...
Almeida, F., Bolla, J., Ehrmann, S., Gault, J., Haag, R., Hoi, K., Liko, I., Pagel, K., Robinson, C., Schweder, M., Shutin, D., Urner, L., Yen, H.   +12 more
core   +2 more sources

Membrane-bending proteins [PDF]

Critical Reviews in Biochemistry and Molecular Biology, 2009
Cellular membranes can assume a number of highly dynamic shapes. Many cellular processes also require transient membrane deformations. Membrane shape is determined by the complex interactions of proteins and lipids. A number of families of proteins that directly bend membranes have been identified.
William A, Prinz, Jenny E, Hinshaw
openaire   +2 more sources

Author Correction: Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

Nature Communications, 2020
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Julia Ast, Anastasia Arvaniti, Nicholas H. F. Fine, Daniela Nasteska, Fiona B. Ashford, Zania Stamataki, Zsombor Koszegi, Andrea Bacon, Ben J. Jones, Maria A. Lucey, Shugo Sasaki, Daniel I. Brierley, Benoit Hastoy, Alejandra Tomas, Giuseppe D’Agostino, Frank Reimann, Francis C. Lynn, Christopher A. Reissaus, Amelia K. Linnemann, Elisa D’Este, Davide Calebiro, Stefan Trapp, Kai Johnsson, Tom Podewin, Johannes Broichhagen, David J. Hodson   +25 more
doaj   +1 more source

Claudin-1 and -2: Novel Integral Membrane Proteins Localizing at Tight Junctions with No Sequence Similarity to Occludin

Journal of Cell Biology, 1998
Occludin is the only known integral membrane protein localizing at tight junctions (TJ), but recent targeted disruption analysis of the occludin gene indicated the existence of as yet unidentified integral membrane proteins in TJ.
M. Furuse, Kohji Fujita, T. Hiiragi, K. Fujimoto, S. Tsukita   +4 more
semanticscholar   +1 more source

Membrane protein serendipity [PDF]

Journal of Biological Chemistry, 2018
My scientific career has taken me from chemistry, via theoretical physics and bioinformatics, to molecular biology and even structural biology. Along the way, serendipity led me to work on problems such as the identification of signal peptides that direct protein trafficking, membrane protein biogenesis, and cotranslational protein folding.
openaire   +3 more sources