Results 31 to 40 of about 10,936,171 (356)
Evaluation of four different strategies to characterize plasma membrane proteins from banana roots [PDF]
, 2015 Plasma membrane proteins constitute a very important class of proteins. They are involved in the transmission of external signals to the interior of the cell and selective transport of water, nutrients and ions across the plasma membrane.
Carpentier, Sebastien C. +3 more
core +1 more source
Binding kinetics of membrane-anchored receptors and ligands: molecular dynamics simulations and theory [PDF]
, 2015 The adhesion of biological membranes is mediated by the binding of membrane-anchored receptor and ligand proteins. Central questions are how the binding kinetics of these proteins is affected by the membranes and by the membrane anchoring of the proteins.
Hu, Jinglei +3 more
core +2 more sources
Pattern formation at cellular membranes by phosphorylation and dephosphorylation of proteins [PDF]
, 2016 We consider a classical model on activation of proteins, based in two reciprocal enzymatic biochemical reactions. The combination of phosphorylation and dephosphorylation reactions of proteins is a well established mechanism for protein activation in ...
Alonso Muñoz, Sergio
core +2 more sources
NMR studies of membrane structure and dynamics [PDF]
, 1978 Over the past decade, there has been considerable interest in the motional state of the phospholipid bilayer membrane. The motivation underlying these efforts has been the contention that the phospholipid bilayer is the basic matrix in which membrane ...
Bocian, David F., Chan, Sunney I.
core +1 more source
eLife, 2023 Allosteric modulation of G protein-coupled receptors (GPCRs) is a major paradigm in drug discovery. Despite decades of research, a molecular-level understanding of the general principles that govern the myriad pharmacological effects exerted by GPCR ...
Ziva Vuckovic +23 more
doaj +1 more source
Sterol transporters at membrane contact sites regulate TORC1 and TORC2 signaling. [PDF]
, 2017 Membrane contact sites (MCSs) function to facilitate the formation of membrane domains composed of specialized lipids, proteins, and nucleic acids. In cells, membrane domains regulate membrane dynamics and biochemical and signaling pathways.
Murley, Andrew +6 more
core +1 more source
Informing β-cell regeneration strategies using studies of heterogeneity
Molecular Metabolism, 2019 Background: Current therapeutic strategies for type 1 (T1DM) and type 2 diabetes mellitus (T2DM) rely on increasing or substituting endogenous insulin secretion in combination with lifestyle changes.
Daniela Nasteska +3 more
doaj +1 more source
Frontiers in Immunology, 2022 IntroductionThe Epidermal Growth Factor Receptor is a member of the Erb receptor tyrosine kinase family. It binds several ligands including EGF, betacellulin (BTC) and TGF-α, controls cellular proliferation and invasion and is overexpressed in various ...
Dehan Comez +12 more
doaj +1 more source
Ubiquilins Chaperone and Triage Mitochondrial Membrane Proteins for Degradation
Molecules and Cells, 2016 Summary We investigated how mitochondrial membrane proteins remain soluble in the cytosol until their delivery to mitochondria or degradation at the proteasome.
Eisuke Itakura +5 more
semanticscholar +1 more source
Detergents and Chaotropes for Protein Solubilization before Two-Dimensional Electrophoresis [PDF]
, 2006 Because of the outstanding separating capabilities of two-dimensional electrophoresis for complete proteins, it would be advantageous to be able to apply it to all types of proteins.
Chevallet, Mireille +3 more
core +4 more sources