Results 21 to 30 of about 495,428 (314)
Since decades plant lipid droplets (LDs) are described as storage organelles accumulated in seeds to provide energy for seedling growth after germination. Indeed, LDs are the site of accumulation for neutral lipids, predominantly triacylglycerols (TAGs),
Imen Bouchnak +4 more
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ENTH domain-dependent membrane remodelling
Cellular membranes are anything but flat structures.
Claudia Steinem, Michael Meinecke
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Optimizing Gō-MARTINI Coarse-Grained Model for F-BAR Protein on Lipid Membrane
Coarse-grained (CG) molecular dynamics (MD) simulations allow us to access much larger length and time scales than atomistic MD simulations, providing an attractive alternative to the conventional simulations.
Md. Iqbal Mahmood +2 more
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Membrane shape remodeling by protein crowding [PDF]
AbstractThe steric repulsion between proteins on biological membranes is one of the most generic mechanisms that cause membrane shape changes. We present a minimal model where a spontaneous curvature is induced by steric repulsion between membrane-associated proteins. Our results show that the interplay between the induced spontaneous curvature and the
Susanne Liese, Andreas Carlson
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Computational Approaches to Explore Bacterial Toxin Entry into the Host Cell
Many bacteria secrete toxic protein complexes that modify and disrupt essential processes in the infected cell that can lead to cell death. To conduct their action, these toxins often need to cross the cell membrane and reach a specific substrate inside ...
Weria Pezeshkian +2 more
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Myosin II filament dynamics in actin networks revealed with interferometric scattering microscopy [PDF]
The plasma membrane and the underlying cytoskeletal cortex constitute active platforms for a variety of cellular processes. Recent work has shown that the remodeling acto-myosin network modifies local membrane organization, but the molecular details are ...
Fineberg, A. +7 more
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Basement membrane remodelling regulates mouse embryogenesis [PDF]
Tissue sculpting during development has been attributed mainly to cellular events through processes such as convergent extension or apical constriction1,2. However, recent work has revealed roles for basement membrane remodelling in global tissue morphogenesis3-5.
Christos Kyprianou +7 more
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Consequences of Folding the Mitochondrial Inner Membrane
A fundamental first step in the evolution of eukaryotes was infolding of the chemiosmotic membrane of the endosymbiont. This allowed the proto-eukaryote to amplify ATP generation while constraining the volume dedicated to energy production.
Carmen A. Mannella
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Interaction of plants with the environment affects lipid metabolism. Changes in the pattern of phospholipids have been reported in response to abiotic stress, particularly accumulation of triacylglycerols, but less is known about the alteration of lipid ...
Sebastian Schieferle +4 more
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Dynamin, a membrane-remodelling GTPase [PDF]
Dynamin, the founding member of a family of dynamin-like proteins (DLPs) implicated in membrane remodelling, has a critical role in endocytic membrane fission events. The use of complementary approaches, including live-cell imaging, cell-free studies, X-ray crystallography and genetic studies in mice, has greatly advanced our understanding of the ...
Shawn M, Ferguson, Pietro, De Camilli
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