Results 11 to 20 of about 1,517,613 (196)
Fluorogenic Probing of Membrane Protein Trafficking [PDF]
Bioconjugate Chemistry, 2018 Methods to differentially label cell-surface and intracellular membrane proteins are indispensable for understanding their function and the regulation of their trafficking. We present an efficient strategy for the rapid and selective fluorescent labeling
Thomas Le Saux (1440580) +11 more
core +6 more sources
Membrane trafficking of ATP-sensitive potassium channels [PDF]
, 2005 ATP-sensitive potassium (KATp) channels are known to play a vital role in the regulation of insulin secretion from pancreatic 0-cells. Changes in the ratio of [ATP]/[ADP] within the cell are known to regulate the activity of channels, but very little is ...
Smith, Andrew James
core +7 more sources
Novel role for proteinase-activated receptor 2 (PAR2) in membrane trafficking of proteinase-activated receptor 4 (PAR4) [PDF]
, 2012 Proteinase-activated receptors 4 (PAR4) is a class A G protein-coupled receptor (GPCR) recognized through the ability of serine proteases such as thrombin and trypsin to mediate receptor activation.
Robben, Joris +9 more
core +4 more sources
Flotillins in membrane trafficking and physiopathology. [PDF]
Biol CellAbstractFlotillin 1 and 2 are highly conserved and homologous members of the stomatin, prohibitin, flotillin, HflK/C (SPFH) family. These ubiquitous proteins assemble into hetero‐oligomers at the cytoplasmic membrane in sphingolipid‐enriched domains. Flotillins play crucial roles in various cellular processes, likely by concentrating sphingosine.
Bodin S +4 more
europepmc +4 more sources
Structure and mechanism in membrane trafficking [PDF]
Current Opinion in Cell Biology, 2010 Cell biologists have long been interested in understanding the machinery that mediates movement of proteins and lipids between intracellular compartments. Much of this traffic is accomplished by vesicles (or other membranous carriers) that bud from one compartment and fuse with another.
Frederick M, Hughson, Karin M, Reinisch
openaire +2 more sources
Editorial overview: Membrane trafficking [PDF]
Current Opinion in Cell Biology, 2019 [No Abstract]
Cullen, Peter J., Nakano, Akihiko
openaire +3 more sources
Membrane trafficking in health and disease [PDF]
Disease Models & Mechanisms, 2020 ABSTRACT Membrane trafficking pathways are essential for the viability and growth of cells, and play a major role in the interaction of cells with their environment. In this At a Glance article and accompanying poster, we outline the major cellular trafficking pathways and discuss how defects in the function of the molecular machinery ...
Rebecca Yarwood +3 more
openaire +5 more sources
A Proteomics Approach to Membrane Trafficking [PDF]
Plant Physiology, 2008 Membrane trafficking, including that of integral membrane proteins as well as peripherally associated proteins, appears to be a vital process common to all eukaryotes. An important element of membrane trafficking is to determine the protein composition of the various endomembrane compartments ...
Groen, A.J. +2 more
openaire +3 more sources
BMC Biology, 2017 Background In a macro-molecular complex, any minor change may prove detrimental. For a supra-molecular nano-machine like the bacterial flagellum, which consists of several distinct parts with specific characteristics, stability is important.
Clive S. Barker +4 more
doaj +1 more source
STAR Protocols, 2020 Summary: Lysosomes are dynamic organelles that serve as regulatory hubs in cellular homeostasis. Changes in lysosome morphology, composition, and turnover are typically linked to disease.
Arun Kumar Tharkeshwar +2 more
doaj +1 more source