Results 41 to 50 of about 1,517,613 (196)
Evolution and Natural History of Membrane Trafficking in Eukaryotes
, 2020 The membrane-trafficking system is a defining facet of eukaryotic cells. The best-known organelles and major protein families of this system are largely conserved across the vast diversity of eukaryotes, implying both ancient organization and functional ...
Klinger, Christen +3 more
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Trafficking to the primary cilium membrane
Molecular Biology of the Cell, 2017 The primary cilium has been found to be associated with a number of cellular signaling pathways, such as vertebrate hedgehog signaling, and implicated in the pathogenesis of diseases affecting multiple organs, including the neural tube, kidney, and brain. The primary cilium is the site where a subset of the cell's membrane proteins is enriched. However,
Mukhopadhyay, Saikat +5 more
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SNARE proteins in membrane trafficking [PDF]
Traffic, 2017 SNAREsare the core machinery mediating membrane fusion. In this review, we provide an update on the recent progress onSNAREsregulating membrane fusion events, especially the more detailed fusion processes dissected by well‐developed biophysical methods and in vitro single molecule analysis approaches.
Tuanlao, Wang +2 more
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Nature CommunicationsRare mutations in the gene encoding presenilin2 (PSEN2) are known to cause familial Alzheimer’s disease (FAD). Here, we explored how altered PSEN2 expression impacts on the amyloidosis, endolysosomal abnormalities, and synaptic dysfunction observed in ...
Anika Perdok +13 more
doaj +1 more source
Molecular Systems Biology, 2011 We manufactured a novel type of lipid‐coated superparamagnetic nanoparticles that allow for a rapid isolation of plasma membranes (PMs), enabling high‐resolution proteomic, glycomic and lipidomic analyses of the cell surface.
Deepak B Thimiri Govinda Raj +15 more
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Studies on the roles of clathrin-mediated membrane trafficking and zinc transporter Cis4 in the transport of GPI-anchored proteins in fission yeast. [PDF]
PLoS ONE, 2012 We previously identified Cis4, a zinc transporter belonging to the cation diffusion facilitator protein family, and we demonstrated that Cis4 is implicated in Golgi membrane trafficking in fission yeast.
Wurentuya Jaiseng +4 more
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Identification of Rab30 as a novel regulator of tubular endosomes
Cell Structure and FunctionTubular-shaped recycling endosomes, known as tubular endosomes, are present in certain types of cells, including HeLa cells, and they regulate the recycling of clathrin-independent endocytosed (CIE) cargo proteins to the plasma membrane.
Shumpei Nakashima, Mitsunori Fukuda
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Bio-Protocol, 2020 The organization and distribution of proteins, lipids, and nucleic acids in eukaryotic cells is an essential process for cell function. Retrograde trafficking from the plasma membrane to the Golgi and endoplasmic reticulum can greatly modify cell ...
Mariska Simpson, Wayne Lencer, Phi Luong
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CaVβ-subunit dependence of forward and reverse trafficking of CaV1.2 calcium channels
Molecular Brain, 2022 Auxiliary CaVβ subunits interact with the pore forming CaVα1 subunit to promote the plasma membrane expression of high voltage-activated calcium channels and to modulate the biophysical properties of Ca2+ currents. However, the effect of CaVβ subunits on
Laurent Ferron +3 more
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Membrane Trafficking Inspired Hydrolysis of Non-Activated Esters at Physiological pH [PDF]
, 2020 Natural enzymes establish the proximity of the substrates to perform challenging reactions in aqueous medium, whereas most chemical catalysts typically follow stochastic way and are less efficient.
Kingshuk, Mahanty +4 more
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