Results 51 to 60 of about 1,517,613 (196)

Therapy-induced senescence in breast cancer: an overview

open access: yesExploration of Targeted Anti-tumor Therapy
Outcomes for women with breast cancer have improved dramatically in recent decades. However, many patients present with intrinsic drug resistance and others are initially sensitive to anti-cancer drugs but acquire resistance during the course of their ...
Suraj Narayanan Chembukavu   +1 more
doaj   +1 more source

A systematic computational analysis of the endosomal recycling pathway in glioblastoma

open access: yesBiochemistry and Biophysics Reports
Glioblastoma (GBM) is the most common and aggressive brain cancer in adults. The standard treatment is brutal and has changed little in 20 years, and more than 85% of patients will die within two years of their diagnosis.
Luke J. Joyce, Andrew J. Lindsay
doaj   +1 more source

Network and Evolutionary Analysis Reveals Candidate Genes of Membrane Trafficking Involved in Maize Seed Development and Immune Response

open access: yesFrontiers in Plant Science, 2022
The plant membrane-trafficking system plays a crucial role in maintaining proper cellular functions and responding to various developmental and environmental cues. Thus far, our knowledge of the maize membrane-trafficking system is still limited. In this
Chunyan Zheng   +4 more
doaj   +1 more source

Membrane Trafficking Components in Cytokinesis [PDF]

open access: yesCellular Physiology and Biochemistry, 2012
Cytokinesis, the last major step of cell division, is a complex multistage process involving specific rearrangement of cellular cytoskeleton and a flurry of vesicular transport activities at the cell division plane. Vesicular traffic from the exocytic pathway and the endocytic/recycling pathway, operating again after being shut down since prophase, are
openaire   +2 more sources

Controlling Cargo Trafficking in Multicomponent Membranes [PDF]

open access: yesNano Letters, 2018
Biological membranes typically contain a large number of different components dispersed in small concentrations in the main membrane phase, including proteins, sugars, and lipids of varying geometrical properties. Most of these components do not bind the cargo.
Curk, Tine   +4 more
openaire   +4 more sources

Trafficking of central opioid receptors and descending pain inhibition

open access: yesMolecular Pain, 2007
The delta-opioid receptor (DOR) belongs to the superfamily of G-protein-coupled receptors (GPCRs) with seven transmembrane domains, and its membrane trafficking is regulated by intracellular sorting processes involving its C-tail motifs, intracellular ...
Pan Zhizhong Z, Bie Bihua
doaj   +1 more source

Establishment of a synchronized tyrosinase transport system revealed a role of Tyrp1 in efficient melanogenesis by promoting tyrosinase targeting to melanosomes

open access: yesScientific Reports
Tyrosinase (Tyr) is a key enzyme in the process of melanin synthesis that occurs exclusively within specialized organelles called melanosomes in melanocytes.
Hikari Nakamura, Mitsunori Fukuda
doaj   +1 more source

Rab GTPases and Membrane Trafficking in Neurodegeneration [PDF]

open access: yesCurrent Biology, 2018
Defects in membrane trafficking are hallmarks of neurodegeneration. Rab GTPases are key regulators of membrane trafficking. Alterations of Rab GTPases, or the membrane compartments they regulate, are associated with virtually all neuronal activities in health and disease.
Kiral, Ferdi Ridvan   +3 more
openaire   +2 more sources

Human trafficking and internet safety

open access: yes, 2023
This flier contains information on human trafficking and internet ...
South Carolina Human Trafficking Task Force
core   +1 more source

Delivery of endocytosed proteins to the cell–division plane requires change of pathway from recycling to secretion

open access: yeseLife, 2014
Membrane trafficking is essential to fundamental processes in eukaryotic life, including cell growth and division. In plant cytokinesis, post-Golgi trafficking mediates a massive flow of vesicles that form the partitioning membrane but its regulation ...
Sandra Richter   +11 more
doaj   +1 more source

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