Results 31 to 40 of about 262,639 (307)
Theory of Cargo and Membrane Trafficking [PDF]
, 2016 Endocytosis underlies many cellular functions including signaling and nutrient uptake. The endocytosed cargo gets redistributed across a dynamic network of endosomes undergoing fusion and fission. Here, a theoretical approach is reviewed which can explain how the microscopic properties of endosome interactions cause the emergent macroscopic properties ...
Foret, Lionel +2 more
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The yeast vacuolar membrane proteome [PDF]
, 2009 Transport of solutes between the cytosol and the vacuolar lumen is of crucial importance for various functions of vacuoles, including ion homeostasis; detoxification; storage of different molecules such as amino acids, phosphate, and calcium ions; and ...
Poolman, Bert, +18 more
core +1 more source
Structure and mechanism in membrane trafficking [PDF]
Current Opinion in Cell Biology, 2010 Cell biologists have long been interested in understanding the machinery that mediates movement of proteins and lipids between intracellular compartments. Much of this traffic is accomplished by vesicles (or other membranous carriers) that bud from one compartment and fuse with another.
Frederick M, Hughson, Karin M, Reinisch
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Distinct human and mouse membrane trafficking systems for sweet taste receptors T1r2 and T1r3. [PDF]
PLoS ONE, 2014 The sweet taste receptors T1r2 and T1r3 are included in the T1r taste receptor family that belongs to class C of the G protein-coupled receptors. Heterodimerization of T1r2 and T1r3 is required for the perception of sweet substances, but little is known ...
Madoka Shimizu +4 more
doaj +1 more source
Cells, 2022 In obesity, chronic membrane-localization of CD36 free fatty acid (FFA) translocase, but not other FFA transporters, enhances FFA uptake and intracellular lipid accumulation.
Nicole K. Nakamura +3 more
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In Vivo Tissue-wide Synchronization of Mitochondrial Metabolic Oscillations
Cell Reports, 2014 Little is known about the spatiotemporal coordination of mitochondrial metabolism in multicellular organisms in situ. Using intravital microscopy in live animals, we report that mitochondrial metabolism undergoes rapid and periodic oscillations under ...
Natalie Porat-Shliom +5 more
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Frontiers in Cell and Developmental Biology, 2021 Membrane trafficking is critical for cellular homeostasis, which is mainly carried out by small GTPases, a class of proteins functioning in vesicle budding, transport, tethering and fusion processes. The accurate and organized membrane trafficking relies
Zehui Lei +5 more
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Diacylglycerol kinases in membrane trafficking [PDF]
Cellular Logistics, 2015 Diacylglycerol kinases (DGKs) belong to a family of cytosolic kinases that regulate the phosphorylation of diacylglycerol (DAG), converting it into phosphatidic acid (PA). There are 10 known mammalian DGK isoforms, each with a different tissue distribution and substrate specificity.
Shuwei, Xie +2 more
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Cholesterol transport from late endosomes to the Golgi regulates t-SNARE trafficking, assembly, and function [PDF]
, 2011 Cholesterol regulates plasma membrane (PM) association and functioning of syntaxin-4 and soluble N-ethylmaleimide-sensitive fusion protein 23 (SNAP23) in the secretory pathway.
Enrich Bastús, Carles +25 more
core +1 more source
Revisiting Rab7 Functions in Mammalian Autophagy: Rab7 Knockout Studies
Cells, 2018 Rab7 (or Ypt7 in yeast) is one of the well-characterized members of the Rab family small GTPases, which serve as master regulators of membrane trafficking in eukaryotes.
Yoshihiko Kuchitsu, Mitsunori Fukuda
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