Results 31 to 40 of about 1,517,613 (196)
Cells, 2022 In obesity, chronic membrane-localization of CD36 free fatty acid (FFA) translocase, but not other FFA transporters, enhances FFA uptake and intracellular lipid accumulation.
Nicole K. Nakamura +3 more
doaj +1 more source
Theory of Cargo and Membrane Trafficking [PDF]
, 2016 Endocytosis underlies many cellular functions including signaling and nutrient uptake. The endocytosed cargo gets redistributed across a dynamic network of endosomes undergoing fusion and fission. Here, a theoretical approach is reviewed which can explain how the microscopic properties of endosome interactions cause the emergent macroscopic properties ...
Foret, Lionel +2 more
openaire +2 more sources
In Vivo Tissue-wide Synchronization of Mitochondrial Metabolic Oscillations
Cell Reports, 2014 Little is known about the spatiotemporal coordination of mitochondrial metabolism in multicellular organisms in situ. Using intravital microscopy in live animals, we report that mitochondrial metabolism undergoes rapid and periodic oscillations under ...
Natalie Porat-Shliom +5 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Membrane trafficking is critical for cellular homeostasis, which is mainly carried out by small GTPases, a class of proteins functioning in vesicle budding, transport, tethering and fusion processes. The accurate and organized membrane trafficking relies
Zehui Lei +5 more
doaj +1 more source
Eeyarestatin 1 interferes with both retrograde and anterograde intracellular trafficking pathways [PDF]
, 2011 Background: The small molecule Eeyarestatin I (ESI) inhibits the endoplasmic reticulum (ER)-cytosol dislocation and subsequent degradation of ERAD (ER associated protein degradation) substrates.
Aletrari, Mina-Olga +28 more
core +2 more sources
Revisiting Rab7 Functions in Mammalian Autophagy: Rab7 Knockout Studies
Cells, 2018 Rab7 (or Ypt7 in yeast) is one of the well-characterized members of the Rab family small GTPases, which serve as master regulators of membrane trafficking in eukaryotes.
Yoshihiko Kuchitsu, Mitsunori Fukuda
doaj +1 more source
Studies on interactions of exported "plasmodium falciparum" membrane proteins [PDF]
, 2014 Responsible for about 700’000 annual deaths worldwide, malaria today is still one of the major health problems in developing countries. The most deadly form of human malaria called malaria tropica is caused by the apicomplexan parasite Plasmodium ...
Dietz, Olivier
core +1 more source
Glycolipid-dependent and lectin-driven transcytosis in mouse enterocytes
Communications Biology, 2021 Ivashenka et al. report that galectin-3 (Gal3) binding to lactotransferrin drives its transcytosis in enterocytes. Such trafficking is Gal3- and glycosphingolipid-dependent, and Gal3 is found in clathrin-independent carriers.
Alena Ivashenka +13 more
doaj +1 more source
Negative regulation of syntaxin4/SNAP-23/VAMP2-mediated membrane fusion by Munc18c In Vitro [PDF]
, 2008 Background: Translocation of the facilitative glucose transporter GLUT4 from an intracellular store to the plasma membrane is responsible for the increased rate of glucose transport into fat and muscle cells in response to insulin.
Nia J Bryant +17 more
core +2 more sources
Impact of sphingolipids on protein membrane trafficking
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2023 Membrane trafficking is essential to maintain the spatiotemporal control of protein and lipid distribution within membrane systems of eukaryotic cells. To achieve their functional destination proteins are sorted and transported into lipid carriers that construct the secretory and endocytic pathways.
Aguilera Romero, María Auxiliadora +3 more
openaire +5 more sources