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Cracking Open Bacterial Membrane Vesicles [PDF]

open access: yesFrontiers in Microbiology, 2020
Membrane vesicles (MVs) are nanoparticles composed of lipid membranes that are produced by both Gram-negative and Gram-positive bacteria. MVs have been assigned diverse biological functions, and they show great potential for applications in various fields.
Toshiki Nagakubo   +4 more
openaire   +4 more sources

Cell membrane-derived vesicles for delivery of therapeutic agents

open access: yesActa Pharmaceutica Sinica B, 2021
Cell membranes have recently emerged as a new source of materials for molecular delivery systems. Cell membranes have been extruded or sonicated to make nanoscale vesicles. Unlike synthetic lipid or polymeric nanoparticles, cell membrane-derived vesicles
Quoc-Viet Le   +4 more
doaj   +2 more sources

Membrane Vesicles as Drug Delivery Systems: MISEV, In Vivo Fluorescence Imaging and Tracking, Specific Tissue Targeting, and Therapeutic Application in Diseases [PDF]

open access: yesPharmaceutics
In the last decade, notable developments have occurred regarding the application of membrane vesicles—encompassing extracellular vesicles (EVs, including exosomes, microvesicles, apoptotic bodies, and others), self-organized cellular-membrane-derived ...
Ying Qin   +7 more
doaj   +2 more sources

Probiotic membrane vesicles: emerging tools for disease treatment. [PDF]

open access: yesMicrobiome Res Rep
Probiotics are widely recognized for their health benefits, particularly in disease prevention and treatment. Recent research suggests that their therapeutic effects may be linked to the bacterial membrane vesicles (bMVs) they release. These nanoscale vesicles, secreted during probiotic growth and metabolism, facilitate intercellular communication ...
Verbunt J, Stassen FRM.
europepmc   +3 more sources

Outer membrane vesicle vaccines [PDF]

open access: yesSeminars in Immunology, 2020
Outer Membrane Vesicles (OMV) have received increased attention in recent years as a vaccine platform against bacterial pathogens. OMV from Neisseria meningitidis serogroup B have been extensively explored. Following the success of the MeNZB OMV vaccine in controlling an outbreak of N.
Francesca, Micoli, Calman A, MacLennan
openaire   +2 more sources

Membrane Vesicles as Drug Delivery Systems: Source, Preparation, Modification, Drug Loading, In Vivo Administration and Biodistribution, and Application in Various Diseases

open access: yesPharmaceutics, 2023
Bioinspired (or biologically inspired) drug delivery systems (DDSs) have been intensively studied in the last decades. As bioinspired DDSs, membrane vesicles, including extracellular vesicles (EVs) released from eukaryotic cells, outer membrane vesicles (
Chenhan Sun   +5 more
doaj   +1 more source

Phospholipid-Membrane-Based Nanovesicles Acting as Vaccines for Tumor Immunotherapy: Classification, Mechanisms and Applications

open access: yesPharmaceutics, 2022
Membrane vesicles, a group of nano- or microsized vesicles, can be internalized or interact with the recipient cells, depending on their parental cells, size, structure and content.
Wenjuan Chen   +7 more
doaj   +1 more source

Secretory vesicles are preferentially targeted to areas of low molecular SNARE density [PDF]

open access: yes, 2012
Intercellular communication is commonly mediated by the regulated fusion, or exocytosis, of vesicles with the cell surface. SNARE (soluble N-ethymaleimide sensitive factor attachment protein receptor) proteins are the catalytic core of the secretory ...
Dun, Alison   +8 more
core   +13 more sources

Cell-sized asymmetric phospholipid-amphiphilic protein vesicles with growth, fission, and molecule transportation

open access: yesiScience, 2023
Summary: Lipid vesicles, which mimic cell membranes in structure and components, have been used to study the origin of life and artificial cell construction.
Masato Suzuki, Koki Kamiya
doaj   +1 more source

Regulation of synaptic vesicle docking by different classes of macromolecules in active zone material. [PDF]

open access: yesPLoS ONE, 2012
The docking of synaptic vesicles at active zones on the presynaptic plasma membrane of axon terminals is essential for their fusion with the membrane and exocytosis of their neurotransmitter to mediate synaptic impulse transmission.
Joseph A Szule   +5 more
doaj   +1 more source

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