Results 221 to 230 of about 534,194 (307)

<i>Porphyromonas gingivalis</i> Bundled Fimbriae Interact with Outer Membrane Vesicles, Commensals and Fibroblasts. [PDF]

Int J Mol Sci
Lambertz J, Buhl EM, Apel C, Preisinger C, Conrads G.   +4 more
europepmc   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Functional Cargo in Membrane Vesicles From a Citrus Pathogen. [PDF]

Environ Microbiol Rep
Araujo GG, Conforte MM, da Purificação AD, Todeschini I, Llontop EE, Angeli CB, Inague A, Yoshinaga MY, de Souza RF, Papai R, Luz MS, Miyamoto S, Palmisano G, Farah CS, Guzzo CR.   +14 more
europepmc   +1 more source

NPM1 Mediates mRNA Sorting into Extracellular Vesicles via Specific RNA Motif Binding and Phase Separation

Advanced Science, EarlyView.
NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang, Gaoge Sun, Xiangzheng Liu, Shuai Zuo, Pengyuan Wang, Boxiao Zhan, Zhi John Lu, Hang Yin, Ying Zhang   +8 more
wiley   +1 more source

The role and mechanism of bacterial outer membrane vesicles in the development of periodontitis. [PDF]

Front Microbiol
Wang H, Sun J, Ma G, You F, Heng BC, Bai Y, Deng X.   +6 more
europepmc   +1 more source

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

Advanced Science, EarlyView.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang, Yizhou Zeng, Yunfeng Chen, Zhengqing Li, Salma Mbarouk Omar, Shengwei Zhong, Ping Liu, Zhanhong Zheng, Gaofeng Cai, Xiaona Gao, Xiaoquan Guo   +10 more
wiley   +1 more source

A brief review of membrane vesicles from <i>Streptococcus mutans</i>. [PDF]

Front Microbiol
Qiu L, Chen Q, Zheng G, Dong H, Xu M, Zhou J, Zhang L, Sun Y, Wang M, Pan Y, Yu J, Pan Y, Zhang K.   +12 more
europepmc   +1 more source

Phase Separation of NFIB Suppresses SLC3A2‐Mediated Ferroptosis in Castration‐Resistant Prostate Cancer

Advanced Science, EarlyView.
Castration‐resistant prostate cancer (CRPC) remains sensitive to ferroptosis, but its intrinsic resistance is poorly understood. Here, we identify NFIB as a master suppressor. SIRT7‐mediated NFIB acetylation drives its liquid–liquid phase separation, which promotes SLC3A2 transcription to inhibit ferroptosis.
Qiunuo Li, Danyang Chen, Yongzhen Xia, Yili Long, Nan Huang, Rongna Li, Mengting Shi, Mairehaba Kadier, Huafeng Luo, Xiaohui Chen, Hao Liu, Guanmin Jiang   +11 more
wiley   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Evaluation of <i>Helicobacter pylori</i>-derived outer membrane vesicles on the expression of inflammatory cytokines. [PDF]

Iran J Microbiol
Mohammadbeigi M, Peymani A, Bolori S, Sotoudeh S, Samimi R, Bakhtiari A, Shegefti S, Bakht M, Badri M, Javadi A, Nikkhahi F.   +10 more
europepmc   +1 more source