Results 251 to 260 of about 2,949,634 (335)

A subset of type 4 secretion system effectors of <i>Brucella</i> spp. associates to outer membrane vesicles. [PDF]

open access: yesMicrolife
Ketterer M   +9 more
europepmc   +1 more source

Biological functions and biogenesis of secreted bacterial outer membrane vesicles.

open access: yesAnnual Review of Microbiology, 2010
Adam Kulp, M. Kuehn
semanticscholar   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang   +4 more
wiley   +1 more source

Preservation of Extracellular Vesicle Integrity and Cargo Using Spiral Microfluidic Chip‐Based Separation

open access: yesAdvanced Materials Technologies, EarlyView.
A spiral microfluidic chip is compared with ultrafiltration for the separation of extracellular vesicles (EVs). The method preserves miRNA cargo and membrane integrity more effectively, resulting in intact vesicle morphology and consistent surface biomarker expression.
Huiseop Lee   +5 more
wiley   +1 more source

In Situ Photopolymerization of Smectic B Liquid‐Crystalline Electrolytes from Mesogenic Phosphate–Diacrylate/Ionic Liquid Complexes for High‐Performance Soft Ionic Actuators

open access: yesAdvanced Robotics Research, EarlyView.
A flexible liquid‐crystalline electrolyte membrane via in situ photopolymerization of a phosphate‐functionalized mesogen, ionic liquid, and diacrylate monomer is developed. The resulting smectic B (SmB)‐phase structure enables 2D ion transport with high conductivity (10−4 S cm−1).
Chengyang Liu, Masafumi Yoshio
wiley   +1 more source

Lactiplantibacillus plantarum Membrane Vesicles (MVs) exhibit immunomodulatory and bactericidal effects against Escherichia coli and Salmonella Typhimurium. [PDF]

open access: yesPLoS One
Lonngi Sosa CD   +10 more
europepmc   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

open access: yesAdvanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann   +26 more
wiley   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

open access: yesAdvanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin   +11 more
wiley   +1 more source

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