Results 51 to 60 of about 311,485 (306)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Validating Membrane Ageing Protocols: A Real‐World Perspective on Vanadium Redox Flow Battery Degradation

ChemElectroChem
Membranes are essential for an efficient and stable long‐term operation of the vanadium redox flow battery (VRFB). Membrane degradation is one of the main limiting factors for VRFB lifetime because of the resulting increase in electrolyte crossover and ...
Felix Lulay, Claudia Weidlich, Adam H. Whitehead, Markus Valtiner, Christian M. Pichler   +4 more
doaj   +1 more source

How Does Carbon Dioxide Permeate Cell Membranes?A discussion of concepts, results and methods.

Frontiers in Physiology, 2014
We review briefly how the thinking about the permeation of gases, especially CO2, across cell and artificial lipid membranes has evolved during the last hundred years.
Volker eEndeward, Samer eAl-Samir, Fabian eItel, Gerolf eGros   +3 more
doaj   +1 more source

Rational ion transport management mediated through membrane structures

Exploration, 2021
Unique membrane structures endow membranes with controlled ion transport properties in both biological and artificial systems, and they have shown broad application prospects from industrial production to biological interfaces.
Yupeng Chen, Zhongpeng Zhu, Ye Tian, Lei Jiang   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Reductionism redux

eLife, 2016
Experiments on artificial membranes are revealing many details about the workings of a family of potassium ion channels called GIRK channels.
Christopher Miller
doaj   +1 more source

Attractive instability of oppositely charged membranes induced by charge density fluctuations

, 2004
We predict the conditions under which two oppositely charged membranes show a dynamic, attractive instability. Two layers with unequal charges of opposite sign can repel or be stable when in close proximity.
A. J. Lin, D. Andelman, E. Sackmann, Guy Hed, M. Doi, R. Lipowsky, R. Merkel, R. N. A. H. Lewis, S. A. Safran, V. A. Parsegian, Y. Kozlovsky   +10 more
core   +1 more source

Tissue engineering a fetal membrane [PDF]

, 2011
The aim of this study was to construct an artificial fetal membrane (FM) by combination of human amniotic epithelial stem cells (hAESCs) and a mechanically enhanced collagen scaffold containing encapsulated human amniotic stromal fibroblasts (hASFs ...
Adam M. Squires, Anna L. David, Bipasha Chowdhury, Che John Connon, Connon C.J., Grinnell F., Ian William Hamley, Jones R.R., Kirkham S.M., Roanne Razalia Jones, Shengli Mi, Trinkaus R.V.   +11 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Human hepatic cell behavior on polysulfone membrane with double porosity level [PDF]

, 2013
In the membrane-based bioartificial livers developed up to now,the hepatic cells were located either in the fibers lumen or in the cartridge,with limited capacity for cell hosting.Here,we designed a polysulfone (PSU) membrane with a double porosity ...
Adrianus, Gerard Nathanael, Aimar, Pierre, Bacchin, Patrice, Cerino, Giulia, Dufresne, Murielle, Legallais, Cécile, Remigy, Jean-Christophe   +6 more
core   +2 more sources