Results 111 to 120 of about 18,395 (294)

New susceptibility Loci associated with kidney disease in type 1 diabetes [PDF]

open access: yes, 2012
Diabetic kidney disease, or diabetic nephropathy (DN), is a major complication of diabetes and the leading cause of end-stage renal disease (ESRD) that requires dialysis treatment or kidney transplantation.
Benjamin J. Keller (135013)   +587 more
core   +1 more source

Protective Effects of Riociguat Against Contrast‐Induced Nephropathy: An Experimental and Machine Learning‐Based Study in Rats

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Contrast‐induced nephropathy (CIN) is an important cause of acute kidney injury following exposure to iodinated contrast media, and effective preventive strategies remain limited. This study investigated the renoprotective effects of riociguat, a soluble guanylate cyclase stimulator, in an experimental rat model of CIN and explored machine ...
Mustafa Begenc Tascanov   +10 more
wiley   +1 more source

From cytokine storm to renal scarring in diabetic kidney disease: Biomarkers, risk stratification, and precision therapeutics

open access: yesPrecision Medical Sciences, EarlyView.
Hyperglycemia‐driven cytokine activation initiates a sustained inflammatory cascade in diabetic kidney disease, promoting cellular injury and fibrogenic signaling. Integrating cytokine‐based biomarkers with risk stratification enables precision therapeutics that target inflammation and fibrosis, ultimately aiming to halt progression from early renal ...
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Diagnosis of membranous nephropathy with Anti-GBM glomerulonephritis: a case series report

open access: yesBMC Nephrology
Background The concomitant occurrence of membranous nephropathy and anti-glomerular basement (anti-GBM) disease has been previously described but is extremely rare.
Ge Liu   +5 more
doaj   +1 more source

Pleural Mesothelioma and Membranous Nephropathy

open access: yesNephron, 2000
Underlying malignancy has been thought to be responsible for 5–10% of the cases of membranous nephropathy in adults, with the risk being highest in patients over the age of 60 years. Solid tumors such as carcinomas of lung or colon, are most often involved.
Galešić, Krešimir   +4 more
openaire   +3 more sources

Anti-glomerular basement membrane disease superimposed on membranous nephropathy: a case report and review of the literature

open access: yesJournal of Medical Case Reports, 2010
Introduction Anti-glomerular basement membrane disease is a rare autoimmune disorder characterized by pulmonary hemorrhage, crescentic glomerulonephritis and the presence of circulating anti-glomerular basement membrane antibodies.
Nivera Noel   +2 more
doaj   +1 more source

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva   +10 more
wiley   +1 more source

Distribution of glomerular diseases in Taiwan: preliminary report of National Renal Biopsy Registry–publication on behalf of Taiwan Society of Nephrology

open access: yesBMC Nephrology, 2018
Background Despite the development of biomarkers and noninvasive imaging tools, biopsy remains the only method for correctly diagnosing patients with unexplained hematuria, proteinuria and renal failure.
Hsien-Fu Chiu   +4 more
doaj   +1 more source

Gut microbiota dysbiosis and Long COVID susceptibility in chronic kidney disease

open access: yesVIEW, EarlyView.
This study investigated gut microbiota dysbiosis and its association with Long COVID susceptibility in 224 hemodialysis patients. We found that 35.3% of patients developed Long COVID, characterized by neurological symptoms and elevated inflammatory markers, accompanied by significant gut microbiota alterations including enriched proinflammatory taxa ...
Meiling Jin   +5 more
wiley   +1 more source

Management of idiopathic membranous nephropathy: Evidence-based recommendations

open access: yes, 1999
Management of idiopathic membranous nephropathy: Evidence-based recommendations. Membranous nephropathy is a frequent cause of nephrotic syndrome in adults, and in one third of these patients, it leads to end-stage renal disease.
Muirhead, Norman
core   +1 more source

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