Results 131 to 140 of about 105,016 (295)

Pathological spectrum of glomerular disease in patients with renal insufficiency: a single-center study in Northeastern China

Renal Failure, 2019
Background: To investigate the pathological spectrum of glomerular disease in patients with renal insufficiency (RI) from 2008 to 2017. Methods and results: We calculated the estimated glomerular filtration rate (eGFR) with the Chronic Kidney Disease ...
Liangmei Chen, Manyu Luo, Changqing Dong, Bing Li, Weiguang Zhang, Ping Nie, Juan Liu, Xiangmei Chen, Ping Luo   +8 more
doaj   +1 more source

Gut microbiota dysbiosis in the inflammatory pathogenesis of diabetic retinopathy

VIEW, EarlyView.
This graphical abstract illustrates how gut dysbiosis drives diabetic retinopathy through the gut‐retina axis, a process unfolding in three interconnected stages. First, in the gut, a decrease in beneficial bacteria and an increase in pro‐inflammatory taxa compromise the intestinal barrier, causing a “leaky gut” that allows LPS to translocate into the ...
Junyan Hu, Jingxiang Zhong
wiley   +1 more source

Efficacy and safety of obinutuzumab as rescue therapy for rituximab-resistant and rituximab-recurrent primary membranous nephropathy: a retrospective cohort study

Open Medicine
With the recognition of membranous nephropathy as an autoimmune disease, targeting B-cells has emerged as an effective therapeutic agent for primary membranous nephropathy (PMN).
Tian Li, Pei Huaying, Dong Tianhua, Zhou Mengsi, Li Shaomei, Zhao Xi, Liang Xuzhi, Xing Lingling   +7 more
doaj   +1 more source

Hypokalemic distal tubulopathy secondary to PLA2R-positive membranous nephropathy: an exceptional case

Glomerular Diseases
Introduction: Primary membranous nephropathy, one of the most common primary nephrotic syndromes in adults, rarely has tubular involvement.
Thanawat Vongchaiudomchoke, Boonyarit Cheunsuchon, Nuttaya Wachiraphansakul   +2 more
doaj   +1 more source

Text mining for case report articles on “peritoneal dialysis” from PubMed database

Therapeutic Apheresis and Dialysis, Volume 29, Issue 3, Page 459-470, June 2025.
Abstract Introduction The number of published medical articles on peritoneal dialysis (PD) has been increasing, and efficiently selecting information from numerous articles can be difficult. In this study, we examined whether artificial intelligence (AI) text mining can be a good support for efficiently collecting PD information.
Kazuhiko Fukushima, Kenji Tsuji, Hiroyuki Nakanoh, Naruhiko Uchida, Soichiro Haraguchi, Shinji Kitamura, Jun Wada   +6 more
wiley   +1 more source

Rutaecarpine Improves Hyperlipidemia‐Related Erectile Dysfunction in Rats by Inhibiting Macrophage M1 Polarization‐Induced Corpus Cavernosum Fibrosis

Andrology, EarlyView.
ABSTRACT Background Hyperlipidemia‐related erectile dysfunction (HLED) responds poorly to first‐line treatments such as phosphodiesterase type 5 inhibitors (PDE5Is), emphasizing the need for alternative therapeutic strategies. Rutaecarpine (RUT), a bioactive alkaloid, exhibits significant anti‐inflammatory and anti‐fibrotic effects.
Bocheng Tu, Shiqing Zhu, Peng Hu, Xiaoyu Zhu, Jiaxin Wang, Xinqi Liu, Sen Fu, Tao Wang, Jihong Liu, Kai Cui   +9 more
wiley   +1 more source

Molecular classification of membranous nephropathy

, 2019
PURPOSE OF REVIEW: Continuous expansion of our knowledge in the pathogenesis of membranous nephropathy possible by the identification of antibodies recognized specific podocytes antigens results in unprecedent patient management strategy. RECENT FINDINGS:
Pozdzik, Agnieszka, Touzani, Fahd, Brochériou, Isabelle, Corazza, Francis   +3 more
core   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Sarcoidosis Presenting with Membranous Nephropathy in a Patient with Hypertensive Nephropathy: Case Report

, 2015
Sarcoidosis is a systemic granulomatous disease that primarily involves the lung but may also have renal involvement. We present a hypertensive nephrosclerosis case found to have sarcoidosis after membranous nephropathy was diagnosed.
Mogulkoc, Nesrin, Tatar, Erhan, Mustafa Yaprak, Gungor, Ozkan, Sarsik, Banu, Sezis Demirci, Meltem, Erhan Tatar, Tamer, Abdulkerim Furkan, Banu Sarsık, Abdülkerim Furkan Tamer, Halil Bozkaya, Özkan Güngör, Meltem Seziş Demirci, Nesrin Moğulkoç, Bozkaya, Halil, Mehmet Nuri Turan, Turan, Mehmet Nuri, Yaprak, Mustafa   +17 more
core   +1 more source

CD93—An emerging vascular target in cancer therapy

British Journal of Pharmacology, EarlyView.
Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira, Stefano Barbera, Roberta Lugano, Anna Dimberg   +3 more
wiley   +1 more source