Results 121 to 130 of about 105,016 (295)

HLA-D and PLA2R1 risk alleles associate with recurrent primary membranous nephropathy in kidney transplant recipients

, 2020
Recurrence of primary membranous nephropathy after transplantation occurs in up to 44% of patients and is driven by PLA2R antibody. Here, we asked whether genetic determinants could improve risk prediction.
Hourmant, Maryvonne, Tesar, Vladimir, Viklický, Ondrej, Brenchley, Paul; id_orcid, Mousson, Christiane, Wetzels, Jack, Dubois, V., Debiec, Hanna, Choukroun, Gabriel, Gandhi, Manish J., Guibert, Sylvain, Mrázová, Petra, Hourmant, M., Brenchley, P., Cruzado, Josep Maria, Debiec, H., Tesar, V., Gandhi, Manish,, Vuiblet, Vincent, Moyer, Ann,, Levi, C., Guibert, S. de, Ronco, P., Mrázová, P., Moyer, Ann M., Letouzé, Eric, Berchtold, L., Torres, Armando, Canaud, Guillaume, Legendre, C., Logt, Anne-Els,, Moulin, B., Ronco, Pierre, Logt, A. van de, Castan, J.A. Ballarín, Yousfi, Nadhir, Cruzado, J.M., Gandhi, M.J., Alexander, M.P., Rieu, Philippe, Logt, Anne-Els van de, Brenchley, Paul, Canaud, G., Moulin, Bruno, OndrejViklický, ., Choukroun, G., Wetzels, J., Letouzé, E., Yousfi, N., Moyer, Ann M, Berchtold, Lena, Dubois, Valérie, Gandhi, Manish, J, Moyer, A.M., Legendre, Christophe, Gandhi, Manish J, Moyer, Ann, M, Ballarín Castan, José Aurelio, Hamilton, Patrick, Vuiblet, V., Rieu, P., Levi, Charlène, Mousson, C., Hamilton, P., Torres, A. Cedillo, Maria Cruzado, Josep, Alexander, Mariam Priya, Choukroun G, Dubois V, Logt AV, Moyer AM, Gandhi MJ, Letouzé E, Cruzado JM, Ronco P, Mrázová P, Moulin B, Debiec H, Wetzels J, Guibert S, Yousfi N, Hourmant M, Canaud G, Hamilton P, Tesar V, Rieu P, Levi C, Brenchley P, Torres A, Ballarín Castan JA, Mousson C, Legendre C, Vuiblet V, Berchtold L, Alexander MP, Viklický O   +95 more
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Astragaloside IV Restores Autophagy and Inhibits Apoptosis for Podocyte Protection in Diabetic Nephropathy by Inhibiting Notch1 Signaling via SIRT6‐Mediated Deacetylation

Phytotherapy Research, EarlyView.
AS‐IV binds to SIRT6 and promotes H3K9 deacetylation at the Notch1 promoter, inhibiting gene transcription (Created with BioGDP.com). ABSTRACT Astragaloside IV (AS‐IV) has demonstrated efficacy in ameliorating proteinuria and attenuating renal tubular damage in preclinical diabetic nephropathy (DN) models.
Qiyu Yue, Chen Yong, Xinran Wang, Yang Shu, Min Yao, Yongfei Yu, Yubai Xue, Rong Deng, Tianlu Chu, Weiwei Tao, Min Zhao, Enchao Zhou   +11 more
wiley   +1 more source

Renal Vein Thrombosis and Membranous Nephropathy - Report of 2 Cases

, 2011
Patients with nephrotic syndrome presents a high risk of arterial and venous thrombosis, mainly deep vein thrombosis and renal vein thrombosis (RVT). We describe two cases of patients with diagnosis of membranous nephropathy and RVT.
Tatiana P Wanderley, Gabriela S Galdino, Germison S Lopes, Denislene S Eduardo, Elizabeth F Daher, Geraldo B Silva   +5 more
core   +1 more source

A mono-center study on pathological types and 15-year epidemiology evolution of primary glomerular diseases

Linchuang shenzangbing zazhi, 2019
Objective To investigate pathological types and the evolutional features of epidemiology of primary glomerular disease in adult patients with renal biopsy in Handan, Hebei, China. Methods From April 2002 to April 2017, a total of 1627 adult patients with
TIAN Kun, DUAN Li-ping, LI Yun, ZHENG Zhao-xia, HU Tian-xiao   +4 more
doaj  

Cinnamic Acid Attenuates Ethanol‐Exacerbated Hepatocyte Pyroptosis in Type 2 Diabetes via AMPK‐Mediated NLRP3/GSDMD Inhibition

Phytotherapy Research, EarlyView.
CA directly binds to and activates AMPK to suppress NLRP3/GSDMD signaling, thereby alleviating hepatocyte pyroptosis in T2DM mice. ABSTRACT Type 2 diabetes mellitus (T2DM) is frequently accompanied by chronic ethanol (ET) consumption, which worsens metabolic dysregulation and organ damage.
Huaiying Tang, Qin Xiang, Yue Zhang, Yu Zhang, Xiangxiang Fu, Liming Tan, Yongli Zhang, Siqi Li, Dong Gong, Xu Guo, Yonghong Zhang, Li Chen, Tao Zheng, Qibin Wang   +13 more
wiley   +1 more source

Obinutuzumab after anti-rituximab antibody-associated treatment failure in membranous nephropathy: a case report

Frontiers in Immunology
Rituximab is an established therapy for primary membranous nephropathy, but anti−rituximab antibodies (ARA) have been associated with rituximab treatment failure.
Jianying Guo, Anni Zhong, Di Wu, Yang Liu, Yuna Chen, Yi Xu, Ricong Xu, Qijun Wan   +7 more
doaj   +1 more source

Protective Effects of Bee Venom (Apis mellifera) Against Cadmium‐Induced Hepatorenal Toxicity, Oxidative Stress, and Anxiety‐Like Behavior in Rats

Environmental Toxicology, EarlyView.
ABSTRACT Cadmium (Cd) is a persistent environmental heavy metal and a major public health concern because it persists in the body for long periods and gradually accumulates in vital organs, particularly the liver, kidneys, and brain. Chronic Cd exposure promotes the excessive production of reactive oxygen species (ROS), which ultimately leads to ...
Soumaya Ghodbane, Chedli Ellijimi, Rym Elfessi, Ranya Hezzi, Khemaies Ben Rhouma, Hafedh Abdelmelek, Najet Srairi‐Abid, Mohsen Sakly, Riadh Marrouchi   +8 more
wiley   +1 more source

Effectiveness of using rituximab in membranous nephropathy: a clinical case

Membranous nephropathy is a glomerulopathy in which the primary target is the podocyte and damage to the glomerular basement membrane. The disease occurs more often in adults, mostly in people over 50 years old.
I.M. Zavalna, Ye.K. Lagodych
core   +1 more source

Elevated urinary excretion of the C5b-9 complex in membranous nephropathy

, 1991
Elevated urinary excretion of the C5b-9 complex in membranous nephropathy. In experimental membranous nephropathy, antibody binding to glomerular epithelial cell membrane antigens results in complement activation and formation of complement C5b-9 ...
Pruchno, Charles J., Gotze, Otto, Martin, Donald C., Baker, Patricia J., Schulze, Matthias, Stahl, Rolf A.K., Wurzner, Reinhard, Couser, William G., Donadio, James V., Johnson, Richard J., Watkins, Sandra   +10 more
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A CASE OF MEMBRANOUS NEPHROPATHY WITH CRESCENTS IN RHEUMATOID ARTHRITIS [PDF]

, 1990
A case of membranous nephropathy with crescents in rheumatoid arthritis is reported. This patient was a 59-year-old male with longstanding rheumatoid arthritis. He developed renal dysfunction, proteinuria and hematuria.
椎木, 英夫, 神元, 章雄, 川野, 貴弘, 吉村, 克敏, 石川, 兵衞, 山中, 富美男, 金内, 雅夫, 土肥, 和紘   +7 more
core   +1 more source